Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zaneta Matuszek"'
Autor:
Pawel Grzechnik, Sylwia A. Szczepaniak, Somdutta Dhir, Anna Pastucha, Hannah Parslow, Zaneta Matuszek, Hannah E. Mischo, Joanna Kufel, Nicholas J. Proudfoot
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Small nucleolar ribonucleoprotein complexes (snoRNP) are fundamental for ribosome biogenesis. Here the authors provide insight into the 5ʹend processing of S. cerevisiae snoRNA and its important role in downstream nuclear events.
Externí odkaz:
https://doaj.org/article/0946a623922b4cfd8113192d0b2a8e39
Autor:
Zaneta Matuszek, Tao Pan
Publikováno v:
Bio-Protocol, Vol 9, Iss 6 (2019)
Queuosine (Q) is a hypermodified base in the wobble anticodon position of tRNAs coding for the amino acids Tyr, His, Asn, and Asp. tRNA Q-modification is introduced by a queuine tRNA-ribosyltransferase (TGT) that replaces the guanine base at G34 at t
Externí odkaz:
https://doaj.org/article/711c141460cc44ebadb5aeab1cd79df8
Autor:
Mandana Arbab, Zaneta Matuszek, Kaitlyn M. Kray, Ailing Du, Gregory A. Newby, Anton J. Blatnik, Aditya Raguram, Michelle F. Richter, Kevin T. Zhao, Jonathan M. Levy, Max W. Shen, W. David Arnold, Dan Wang, Jun Xie, Guangping Gao, Arthur H. M. Burghes, David R. Liu
Publikováno v:
Science. 380
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality, arises from survival motor neuron (SMN) protein insufficiency resulting from SMN1 loss. Approved therapies circumvent endogenous SMN regulation and require repeated dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da790fc009f5f996838b159db859f45f
https://doi.org/10.1126/science.adg6518
https://doi.org/10.1126/science.adg6518
Autor:
Max W. Shen, Mandana Arbab, Peyton B. Randolph, Tony P. Huang, Gregory A. Newby, Zaneta Matuszek, Tina Wang, Holly A. Rees, David R. Liu, Shannon M. Miller
Publikováno v:
Nature biotechnology
The targeting scope of Streptococcus pyogenes Cas9 (SpCas9) and its engineered variants is largely restricted to protospacer-adjacent motif (PAM) sequences containing Gs. Here, we report the evolution of three new SpCas9 variants that collectively re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4854f8fda8cc240d332cdf315fc1e91
https://doi.org/10.1038/s41587-020-0412-8
https://doi.org/10.1038/s41587-020-0412-8
Autor:
Huihao Zhou, Bernhard Kuhle, Jingjing Zhang, Zaneta Matuszek, Litao Sun, Rita Horvath, Paul Schimmel, David Blocquel, Tao Pan, Na Wei, Thomas Weber, Philippe Latour, Xiang-Lei Yang, Weiwei He, Patrick R. Griffin, Scott J. Novick
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Charcot-Marie-Tooth disease (CMT) is a devastating motor and sensory neuropathy with an estimated 100,000 afflicted individuals in the US. Unexpectedly, aminoacyl-tRNA synthetases are the largest disease-associated protein family. A natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd45dff9c50fd9cf3a512aba7650922
https://doi.org/10.1073/pnas.2012898118
https://doi.org/10.1073/pnas.2012898118
Autor:
Zaneta Matuszek, David Blocquel, Bernhard Kuhle, Litao Sun, Na Wei, Thomas Weber, Sheng Li, Xiang-Lei Yang, Grace Kooi, Jonathan Baets, Paul Schimmel, Tao Pan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Aminoacyl-transfer RNA (tRNA) synthetases (aaRSs) are the largest protein family causatively linked to neurodegenerative Charcot–Marie–Tooth (CMT) disease. Dominant mutations cause the disease, and studies of CMT disease-causing mutant glycyl-tRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544659d54080e02e0a0c1df1ac1780a6
https://europepmc.org/articles/PMC6765236/
https://europepmc.org/articles/PMC6765236/
Autor:
Tao Pan, Zaneta Matuszek
Publikováno v:
Bio Protoc
Queuosine (Q) is a hypermodified base in the wobble anticodon position of tRNAs coding for the amino acids Tyr, His, Asn, and Asp. tRNA Q-modification is introduced by a queuine tRNA-ribosyltransferase (TGT) that replaces the guanine base at G34 at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc140c274e25d5d3bf4e3ad05f0c398
https://pubmed.ncbi.nlm.nih.gov/33654991
https://pubmed.ncbi.nlm.nih.gov/33654991
Autor:
Xiaoyun Wang, Yong Huang, Tao Pan, Michael H. Schwartz, Wesley C. Clark, Zaneta Matuszek, Marc Parisien, Qing Dai
Publikováno v:
RNA (New York, N.Y.). 24(10)
Eukaryotic transfer RNAs (tRNA) contain on average 13 modifications that perform a wide range of roles in translation and in the generation of tRNA fragments that regulate gene expression. Queuosine (Q) modification occurs in the wobble anticodon pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553e3cf927896280e64cc4964ad616e0
https://pubmed.ncbi.nlm.nih.gov/29970597
https://pubmed.ncbi.nlm.nih.gov/29970597
Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing
Autor:
Marina Falaleeva, Zaneta Matuszek, Amadís Pagès, Ruth Sperling, Yuval Nevo, Stefan Stamm, Lily Agranat-Tamir, Eduardo Eyras, Konstantin V. Korotkov, Sana Hidmi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(12)
Significance C/D box small nucleolar RNAs (SNORDs) are abundant, short, nucleoli-residing, noncoding RNAs that guide the methyltransferase fibrillarin to perform 2′- O -methylation of target RNAs. We identified 29 SNORDs present in a fibrillarin-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45108f5e566d53ff4954507edfac8cd8
https://pubmed.ncbi.nlm.nih.gov/26957605
https://pubmed.ncbi.nlm.nih.gov/26957605
Publikováno v:
The FASEB Journal. 29
Small nucleolar RNAs (snoRNAs) are the best characterized non-coding RNAs transcribed by RNA polymerase II. They are produced as precursors, whose extended 3' ends are trimmed exonucleolytically, whereas 5' ends either undergo combined endo- and exon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6dfd6fac6506d7600b5629ddad2df7f
https://doi.org/10.1096/fasebj.29.1_supplement.lb223
https://doi.org/10.1096/fasebj.29.1_supplement.lb223