In vitro models of the human blood-brain barrier and the impact of efflux transporters on neurological disorders: the work of Cioni et al. (2012)A commentary on: Expression of tight junction and drug efflux transporter proteins in an in vitro model of human blood-brain barrierCioni C, Turlizzi E, Zanelli U, Oliveri G, Annunziata P. Front. Psychiatry 2012; 3, 47

Autor: Silke eVogelgesang, Gabriele eJedlitschky

Publikováno v: Frontiers in Psychiatry, Vol 5 (2014)

Externí odkaz: https://doaj.org/article/5e57a3e7a8f04034b4dcd9fa600e96d0

Identification of unknown impurities J, RRT 2.2, 2.4, 2.6 and 3.4 in tetralysal® capsules.

Autor: Billié S; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Reversé K; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Arlabosse JM; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Bertin D; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Boulier A; Laboratoires Galderma SAS, ZI Montdésir, Alby-sur-Chéran 74540, France., Cachot T; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Chambon S; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Charras K; Laboratoires Galderma SAS, ZI Montdésir, Alby-sur-Chéran 74540, France. Electronic address: karine.charras@galderma.com., Cren C; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Furnes B; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Gerfaud T; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Joly-Battaglini M; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Longoni D; Olon SpA, Strada Rivoltana, km 6/7, Rodano, Milan 20053, Italy., Mouis G; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Pierre R; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Raynard H; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Texier T; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France., Trognon C; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Zanelli U; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland., Boiteau JG; Nuvisan France SARL - CS 10287, Sophia-Antipolis 06905, France. Electronic address: Jean-Guy.Boiteau@nuvisan.com., Harris CS; Galderma SA, Av. d'Ouchy 4, Lausanne 1006, Switzerland. Electronic address: craigstevenharris@gmail.com.

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2023 Sep 01; Vol. 188, pp. 106519. Date of Electronic Publication: 2023 Jul 19.

Stabilization of cytochrome P4502E1 protein by ethanol in primary hamster hepatocyte cultures

Autor: Zanelli, U ^a, Longo, V ^a, Paolicchi, A ^b, Gervasi, P.G ^{a, *}

Publikováno v: In Toxicology in Vitro 2000 14(1):69-77

Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i).

Autor: Klein M; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Busch M; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Friese-Hamim M; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Crosignani S; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Fuchss T; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Musil D; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Rohdich F; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Sanderson MP; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Seenisamy J; Syngene International Limited, Biocon Park, Plot2&3, Bommasandra-Jigani Link Road, Bangalore 560 099, India., Walter-Bausch G; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Zanelli U; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Hewitt P; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Esdar C; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany., Schadt O; Merck KGaA, Frankfurter Str. 250, Darmstadt 64293, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Jul 22; Vol. 64 (14), pp. 10230-10245. Date of Electronic Publication: 2021 Jul 06.

Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance.

Autor: Gouliarmou V; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Lostia AM; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Coecke S; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy. Electronic address: sandra.coecke@ec.europa.eu., Bernasconi C; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Bessems J; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Dorne JL; European Food Safety Authority, Via Carlo Magno, 1A, 43126 Parma, PR, Italy., Ferguson S; US National Toxicology Program, National Institute of Environmental Health Sciences, Durham, NC 27709, USA., Testai E; Istituto Superiore di Sanità, Environment & Health Dept., Viale Regina Elena 299, 00161 Rome, Italy., Remy UG; Institute for Clinical Pharmacology and Toxicology, Charité, Universitätsmedizin Berlin, Charitéplatz 1, D-110117 Berlin, Germany., Brian Houston J; Manchester Pharmacy School, University of Manchester, Manchester M13 9PT, UK., Monshouwer M; Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium., Nong A; Computational Toxicology Laboratory, Exposure and Biomonitoring Division, Health Canada - Environmental Health Science and Research Bureau, 50 Colombine Dwy, Environmental Health Centre, Tunney's Pasture AL:0800C, Ottawa, ON K1A 0K9, Canada., Pelkonen O; Research Unit of Biomedicine/Pharmacology and Toxicology, Faculty of Medicine, Aapistie 5 B, FIN-90014, University of Oulu, Finland., Morath S; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Wetmore BA; U.S. EPA, Office of Research and Development, National Exposure Research Laboratory, 109 T.W. Alexander Drive, MD E243-04, Research Triangle Park, NC 27711, USA., Worth A; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Zanelli U; Discovery DMPK, Merck KGaA Darmstadt, Germany., Zorzoli MC; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy., Whelan M; European Commission, Joint Research Centre (JRC), Via Enrico Fermi 2749, 21027 Ispra, VA, Italy.

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2018 Dec; Vol. 53, pp. 233-244. Date of Electronic Publication: 2018 Aug 09.