Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model

Autor: Ahmad Parvinian,, Leigh C. Casadaban,, Zane Z. Hauck,, Richard B. van Breemen,, Ron C. Gaba

Publikováno v: Diagnostic and Interventional Radiology, Vol 21, Iss 3, Pp 235-240 (2015)

PURPOSEUse of oral sorafenib, an antiangiogenic chemotherapeutic agent for hepatocellular carcinoma (HCC), is limited by an unfavorable side effect profile. Transarterial chemoembolization (TACE) employs targeted intravascular drug administration, an

Externí odkaz: https://doaj.org/article/2a79c3a694cd4ef29f4ab8e27d47db56

Differentiating Between CAH and PCOS Using Hormone Levels and LC-MS/MS

Autor: David W Kimball, David Zava, Zane Z Hauck

Publikováno v: Journal of the Endocrine Society

Introduction: PCOS is one of the most common endocrine issues affecting women today, with almost 10% of women suffering from this condition. CAH is a rarer disease that affects both men and women at a rate of around 1:1000 people. The problem with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d9cdd104c29583ba37238b63333049
https://doi.org/10.1210/jendso/bvab048.255

Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry

Autor: Ke Huang, Guannan Li, Zane Z. Hauck, Richard B. van Breemen

Publikováno v: Rapid Communications in Mass Spectrometry. 30:400-406

Rationale Used widely as a plasticizer and as a monomer for plastics, bisphenol A (BPA) is under investigation as a possible endocrine disrupter. As an indication of systemic exposure, a fast and accurate assay was developed for the major BPA metabol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c18b4ae7affa7da45528d839b0b90dc
https://doi.org/10.1002/rcm.7450

Quantitation of major indole and oxindole alkaloids from different kratom (Mitrigyna speciosa) strain extracts using UHPLC-MS/MS

Autor: DG Nosal, Zane Z. Hauck, RB van Breemen

Publikováno v: Planta Medica. 81

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1fa8dad77ac4a55dbe0f701d46d3e6e
https://doi.org/10.1055/s-0035-1556371

Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.

Autor: Marshall MS; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Issa Y; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Jakubauskas B; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Stoskute M; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Elackattu V; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Marshall JN; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Bogue W; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Nguyen D; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Hauck Z; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Rue E; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Karumuthil-Melethil S; Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Zaric V; Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bosland M; Department of Pathology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., van Breemen RB; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Givogri MI; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Gray SJ; Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Crocker SJ; Department of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA., Bongarzone ER; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA; Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 1053 Buenos Aires, Argentina. Electronic address: ebongarz@uic.edu.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2018 Mar 07; Vol. 26 (3), pp. 874-889. Date of Electronic Publication: 2018 Jan 17.