Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zane Coleman"'
Autor:
Yanan Li, Jeffrey Steinberg, Zane Coleman, Shubo Wang, Chitra Subramanian, Yimei Li, Zoltan Patay, Walter Akers, Charles O. Rock, Suzanne Jackowski, Puneet Bagga
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-7 (2022)
Abstract Background Pantothenate kinase (PANK) is the first and rate-controlling enzymatic step in the only pathway for cellular coenzyme A (CoA) biosynthesis. PANK-associated neurodegeneration (PKAN), formerly known as Hallervorden–Spatz disease,
Externí odkaz:
https://doaj.org/article/f471643e687d4de7b4380850486b58d0
Autor:
Mamta Rai, Michelle Curley, Zane Coleman, Anjana Nityanandam, Jianqin Jiao, Flavia A. Graca, Liam C. Hunt, Fabio Demontis
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100628- (2021)
Summary: Defects in protein quality control are the underlying cause of age-related diseases. The western blot analysis of detergent-soluble and insoluble protein fractions has proven useful in identifying interventions that regulate proteostasis. He
Externí odkaz:
https://doaj.org/article/ca4e981144da47cfa6ff526512179354
Publikováno v:
Aging Cell. 21
Protein quality control ensures the degradation of damaged and misfolded proteins. Derangement of proteostasis is a primary cause of aging and age-associated diseases. The ubiquitin-proteasome and autophagy-lysosome play key roles in proteostasis but
Autor:
Yanan Li, Jeffrey Steinberg, Zane Coleman, Shubo Wang, Chitra Subramanian, Yimei Li, Zoltan Patay, Walter Akers, Charles O. Rock, Suzanne Jackowski, Puneet Bagga
Publikováno v:
Journal of translational medicine. 20(1)
Background Pantothenate kinase (PANK) is the first and rate-controlling enzymatic step in the only pathway for cellular coenzyme A (CoA) biosynthesis. PANK-associated neurodegeneration (PKAN), formerly known as Hallervorden–Spatz disease, is a rare
Autor:
Liam C. Hunt, Fabio Demontis, Michelle Curley, Anjana Nityanandam, Flavia A. Graca, Zane Coleman, Mamta Rai, Jianqin Jiao
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 3, Pp 100628-(2021)
STAR Protocols, Vol 2, Iss 3, Pp 100628-(2021)
Summary Defects in protein quality control are the underlying cause of age-related diseases. The western blot analysis of detergent-soluble and insoluble protein fractions has proven useful in identifying interventions that regulate proteostasis. Her
Autor:
Anjana Nityanandam, David Finkelstein, Yiping Fan, Zane Coleman, Michelle Curley, Mamta Rai, Jianqin Jiao, Maricela Robles-Murguia, Anna Platt, Fabio Demontis, Beisi Xu, Yong-Dong Wang
Publikováno v:
Cell Metabolism. 33:1137-1154.e9
Neurodegeneration in the central nervous system (CNS) is a defining feature of organismal aging that is influenced by peripheral tissues. Clinical observations indicate that skeletal muscle influences CNS aging, but the underlying muscle-to-brain sig
Autor:
Robert B. Akins, Jon L. Schindler, Kevin W. Jelley, George T. Valliath, Zane Coleman, R. Polak
Publikováno v:
SID Symposium Digest of Technical Papers. 29:1139
Transmission holographic film for brightness enhancement in full color reflective LCDs is proposed. The hologram is attached to the front of the LCD. The goal is paper-like brightness within the viewing zone under typical ambient lighting conditions.