Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zane A Jaafar"'
Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling
Publikováno v:
eLife, Vol 5 (2016)
Internal ribosome entry sites (IRESs) are important RNA-based translation initiation signals, critical for infection by many pathogenic viruses. The hepatitis C virus (HCV) IRES is the prototype for the type 3 IRESs and is also invaluable for explori
Externí odkaz:
https://doaj.org/article/91c56e38cbae40e5a6810bd79def51ad
Autor:
H. Broder Schmidt, Zane A. Jaafar, B. Erik Wulff, Jason J. Rodencal, Kibeom Hong, Mohammad O. Aziz-Zanjani, Peter K. Jackson, Manuel D. Leonetti, Scott J. Dixon, Rajat Rohatgi, Onn Brandman
Publikováno v:
Cell reports, vol 41, iss 6
Platinum (Pt) compounds such as oxaliplatin are among the most commonly prescribed anti-cancer drugs. Despite their considerable clinical impact, the molecular basis of platinum cytotoxicity and cancer specificity remain unclear. Here we show that ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1feb3218ab03b38ddc4c3a3ca960a908
https://doi.org/10.1016/j.celrep.2022.111629
https://doi.org/10.1016/j.celrep.2022.111629
Autor:
Zane A. Jaafar, Jeffrey S. Kieft
Publikováno v:
Nature Reviews Microbiology
Viruses must co-opt the cellular translation machinery to produce progeny virions. Eukaryotic viruses have evolved a variety of ways to manipulate the cellular translation apparatus, in many cases using elegant RNA-centred strategies. Viral RNAs can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a880a275091e989df3f8c8f0f65d64
https://pubmed.ncbi.nlm.nih.gov/30514982
https://pubmed.ncbi.nlm.nih.gov/30514982
Publikováno v:
Biochemistry. 48:10353-10361
Chlamydia are obligate intracellular bacterial pathogens that cause a variety of diseases. Like many Gram-negative bacteria, they employ type III secretion systems (T3SS) for invasion, establishing and maintaining their unique intracellular niche, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b842b05eee3ae72bec81e7022a5e10
https://doi.org/10.1021/bi901200y
https://doi.org/10.1021/bi901200y
Autor:
David A. Costantino, Jeffrey S. Kieft, Harry F. Noller, Terra-Dawn M. Plank, Zane A. Jaafar, John Paul Donohue, Timothy M. Colussi, Andrei A. Korostelev, Jianyu Zhu
Publikováno v:
Nature
The central dogma of gene expression (DNA to RNA to protein) is universal, but in different domains of life there are fundamental mechanistic differences within this pathway. For example, the canonical molecular signals used to initiate protein synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210e6a394e522a6022feaf77265fb0f5
https://pubmed.ncbi.nlm.nih.gov/25652822
https://pubmed.ncbi.nlm.nih.gov/25652822