Killer meiotic drive executed by two alternative conformations of a single protein.

Autor: Zanders SE; Stowers Institute for Biomedical Research, Kansas City, MO 64110.; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, KS 66103., Smith GR; Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Dec 10; Vol. 121 (50), pp. e2420620121. Date of Electronic Publication: 2024 Dec 02.

Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen Cryptococcus neoformans .

Autor: Billmyre RB; Department of Pharmaceutical and Biological Sciences, College of Pharmacy, University of Georgia, GA, United States.; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, GA, United States.; Department of Microbiology, Franklin College of Arts and Sciences, University of Georgia, GA, United States.; Department of Genetics, Franklin College of Arts and Sciences, University of Georgia, GA, United States.; Stowers Institute for Medical Research, Kansas City, MO, USA., Craig CJ; Stowers Institute for Medical Research, Kansas City, MO, USA., Lyon J; Department of Pharmaceutical and Biological Sciences, College of Pharmacy, University of Georgia, GA, United States.; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, GA, United States., Reichardt C; Department of Pharmaceutical and Biological Sciences, College of Pharmacy, University of Georgia, GA, United States.; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, GA, United States.; Department of Microbiology, Franklin College of Arts and Sciences, University of Georgia, GA, United States., Eickbush MT; Stowers Institute for Medical Research, Kansas City, MO, USA., Zanders SE; Stowers Institute for Medical Research, Kansas City, MO, USA.; Department of Cell Biology and Physiology, University of Kansas Medical Center, KS, United States.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 06. Date of Electronic Publication: 2024 Aug 06.

Genome-wide quantification of contributions to sexual fitness identifies genes required for spore viability and health in fission yeast.

Autor: Billmyre RB; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Eickbush MT; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Craig CJ; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Lange JJ; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Wood C; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Helston RM; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Zanders SE; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2022 Oct 27; Vol. 18 (10), pp. e1010462. Date of Electronic Publication: 2022 Oct 27 (Print Publication: 2022).

What can we learn from selfish loci that break Mendel's law?

Autor: Zanders SE; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States of America.

Publikováno v: PLoS biology [PLoS Biol] 2022 Jul 19; Vol. 20 (7), pp. e3001700. Date of Electronic Publication: 2022 Jul 19 (Print Publication: 2022).

The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death.

Autor: Nuckolls NL; Stowers Institute for Medical Research, Kansas City, United States., Mok AC; Stowers Institute for Medical Research, Kansas City, United States.; University of Missouri-Kansas City, Kansas City, United States., Lange JJ; Stowers Institute for Medical Research, Kansas City, United States., Yi K; Stowers Institute for Medical Research, Kansas City, United States., Kandola TS; Stowers Institute for Medical Research, Kansas City, United States.; Open University, Milton Keynes, United Kingdom., Hunn AM; Stowers Institute for Medical Research, Kansas City, United States., McCroskey S; Stowers Institute for Medical Research, Kansas City, United States., Snyder JL; Stowers Institute for Medical Research, Kansas City, United States., Bravo Núñez MA; Stowers Institute for Medical Research, Kansas City, United States., McClain M; Stowers Institute for Medical Research, Kansas City, United States., McKinney SA; Stowers Institute for Medical Research, Kansas City, United States., Wood C; Stowers Institute for Medical Research, Kansas City, United States., Halfmann R; Stowers Institute for Medical Research, Kansas City, United States.; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, United States., Zanders SE; Stowers Institute for Medical Research, Kansas City, United States.; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, United States.

Publikováno v: ELife [Elife] 2020 Oct 27; Vol. 9. Date of Electronic Publication: 2020 Oct 27.