Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis

Autor: Salmond, RJ, Brownlie, RJ, Zamoyska, R

Publikováno v: Cell Cycle
Salmond, R J, Brownlie, R J & Zamoyska, R 2015, ' Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis ', Cell Cycle, vol. 14, no. 5, pp. 705-11 . https://doi.org/10.1080/15384101.2015.1007018

The non-receptor tyrosine phosphatase PTPN22 has a vital function in inhibiting antigen-receptor signaling in T cells, while polymorphisms in the PTPN22 gene are important risk alleles in human autoimmune diseases. We recently reported that a key phy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3d58d5560c267e6ab719f0d6090810ba
http://europepmc.org/articles/PMC4671365

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

Autor: Zamoyska, R., M. Albert Basson, Filby, A., Legname, G., Lovatt, M., Seddon, B.

Publikováno v: King's College London

The src-family kinases p56lck (Lck) and p59fyn (Fyn) are expressed in T cells and are among the first signaling molecules to be activated downstream of the T cell receptor (TCR). Evidence is emerging that although closely related, these signaling mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::be85abbcef35f4929a90f19b05dc75a0
http://hdl.handle.net/20.500.11767/16906

A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice

Autor: Hostert, A., Tolaini, M., Festenstein, R., Mcneill, L., Bernard Malissen, Williams, O., Zamoyska, R., Kioussis, D.

Publikováno v: Europe PubMed Central
Publons

Helper and cytotoxic T cell subsets require the expression of different coreceptors (CD4 and CD8, respectively) for their development and function. We have cloned the CD8 gene locus from genomic cosmid and P1 libraries and analyzed the region around

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfdc92e4d4367d00290893c09029fb1
https://pubmed.ncbi.nlm.nih.gov/9126989