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Akademický článek

Oral spleen tyrosine kinase/Janus Kinase inhibitor gusacitinib for the treatment of chronic hand eczema: Results of a randomized phase 2 study.

Autor: Jimenez PA; Asana BioSciences, Lawrenceville, New Jersey. Electronic address: pablo.jimenez@asanabio.com., Sofen HL; Department of Medicine/Dermatology, UCLA School of Medicine, Los Angeles, California., Bissonnette R; Innovaderm Research, Montreal, Quebec, Canada., Lee M; Progressive Clinical Research, San Antonio, Texas., Fowler J; Division of Dermatology, University of Louisville School of Medicine, Louisville, Kentucky., Zammit DJ; Asana BioSciences, Lawrenceville, New Jersey., Chen Y; Asana BioSciences, Lawrenceville, New Jersey., Rao N; Asana BioSciences, Lawrenceville, New Jersey., Denis L; Asana BioSciences, Lawrenceville, New Jersey., Gupta S; Asana BioSciences, Lawrenceville, New Jersey.

Publikováno v: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2023 Aug; Vol. 89 (2), pp. 235-242. Date of Electronic Publication: 2023 Apr 23.

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Akademický článek

ASN004, A 5T4-targeting scFv-Fc Antibody-Drug Conjugate with High Drug-to-Antibody Ratio, Induces Complete and Durable Tumor Regressions in Preclinical Models.

Autor: Smith RA; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey. roger.smith@asanabio.com., Zammit DJ; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Damle NK; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Usansky H; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Reddy SP; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Lin JH; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Mistry M; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Rao NS; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Denis LJ; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey., Gupta S; Asana BioSciences, Princeton Pike Corporate Center, Lawrenceville, New Jersey.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Aug; Vol. 20 (8), pp. 1327-1337. Date of Electronic Publication: 2021 May 27.

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Akademický článek

The oral Janus kinase/spleen tyrosine kinase inhibitor ASN002 demonstrates efficacy and improves associated systemic inflammation in patients with moderate-to-severe atopic dermatitis: results from a randomized double-blind placebo-controlled study.

Autor: Bissonnette R; Innovaderm Research Inc., 1851 Sherbrooke Street East, Suite 502, Montreal, H2K 4L5, Quebec, Canada., Maari C; Innovaderm Research Inc., 1851 Sherbrooke Street East, Suite 502, Montreal, H2K 4L5, Quebec, Canada., Forman S; Forward Clinical Trials, Inc., 4915 Ehrlich Road, Tampa, 33624, FL, U.S.A., Bhatia N; Therapeutics Clinical Research, 9025 Balboa Avenue, Suite 105, San Diego, 92123, CA, U.S.A., Lee M; Progressive Clinical Research, P.A., LLC, 1973 North West Loop 410, Suite 106, San Antonio, 78213, TX, U.S.A., Fowler J; Dermatology Specialists Research, 3810 Springhurst Boulevard, Suite 130, Louisville, 40241, KY, U.S.A., Tyring S; Center for Clinical Studies, University of Texas Health Science Center, 451 North Texas Avenue, Houston, 77598, TX, U.S.A., Pariser D; Department of Dermatology, Eastern Virginia Medical School and Virginia Clinical Research Inc., 6160 Kempsville Circle, Suite 200A, Norfolk, 23502, VA, U.S.A., Sofen H; Dermatology Research Associates, 8930 South Sepulveda Boulevard, Los Angeles, 90045, CA, U.S.A., Dhawan S; Center for Dermatology Clinical Research Inc., 2557 Mowry Avenue, Suite 21 and 25, Fremont, 94538, CA, U.S.A., Zook M; Olympian Clinical Research, 1201 South Myrtle Avenue, Clearwater, 33756, FL, U.S.A., Zammit DJ; Asana BioSciences, LLC, 997 Lenox Drive, Suite 220, Princeton Pike Corporate Center, Lawrenceville, 08648, NJ, U.S.A., Usansky H; Asana BioSciences, LLC, 997 Lenox Drive, Suite 220, Princeton Pike Corporate Center, Lawrenceville, 08648, NJ, U.S.A., Denis L; Asana BioSciences, LLC, 997 Lenox Drive, Suite 220, Princeton Pike Corporate Center, Lawrenceville, 08648, NJ, U.S.A., Rao N; Asana BioSciences, LLC, 997 Lenox Drive, Suite 220, Princeton Pike Corporate Center, Lawrenceville, 08648, NJ, U.S.A., Song T; Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Icahn Building 13-76, New York, 10029, NY, U.S.A., Pavel AB; Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Icahn Building 13-76, New York, 10029, NY, U.S.A., Guttman-Yassky E; Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Icahn Building 13-76, New York, 10029, NY, U.S.A.

Publikováno v: The British journal of dermatology [Br J Dermatol] 2019 Oct; Vol. 181 (4), pp. 733-742. Date of Electronic Publication: 2019 May 06.

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Akademický článek

Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis.

Autor: Pavel AB; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Song T; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Kim HJ; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Del Duca E; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Krueger JG; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Dubin C; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Peng X; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Xu H; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Zhang N; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Estrada YD; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY., Denis L; Asana Biosciences, Princeton, NJ., Rao N; Asana Biosciences, Princeton, NJ., Gupta S; Asana Biosciences, Princeton, NJ., Zammit DJ; Asana Biosciences, Princeton, NJ., Bissonnette R; Innovaderm Research, Montreal, Quebec, Canada., Guttman-Yassky E; Department of Dermatology, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: emma.guttman@mountsinai.org.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2019 Oct; Vol. 144 (4), pp. 1011-1024. Date of Electronic Publication: 2019 Jul 26.

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