Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zamia Siddiqui"'
Autor:
Kornelia J. Skowron, Kiira Ratia, Atul D. Jain, Phillip R. Lazzara, Amanda C Maldonado, Benjamin G. Richardson, Brian P. David, Zamia Siddiqui, Terry W. Moore
Publikováno v:
ACS Med Chem Lett
[Image: see text] The oxidative stress response, gated by the protein–protein interaction of KEAP1 and NRF2, has garnered significant interest in the past decade. Misregulation in this pathway has been implicated in disease states such as multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef2827714d80a88db572e0b81460062
https://europepmc.org/articles/PMC7153276/
https://europepmc.org/articles/PMC7153276/
Autor:
Sean W. Fanning, Zamia Siddiqui, Terry W. Moore, Emad Tajkhorshid, Geoffrey L. Greene, Christopher G. Mayne, Thomas E. Speltz
Publikováno v:
Organic & Biomolecular Chemistry. 16:3702-3706
A new computational approach to obtain quantitative energy profiles for helix folding was used in the design of orthogonal hydrocarbon and lactam bicyclic peptides. The proteolytically stable, "cross-stitched" peptide SRC2-BCP1 shows nanomolar affini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40f145e38726c53ba7e1af964c73eee
https://doi.org/10.1039/c8ob00790j
https://doi.org/10.1039/c8ob00790j
Autor:
Terry W. Moore, Thomas E. Speltz, Simone M. Creed, Amy Lian, Changfeng Cheng, Phillip R. Lazzara, Brian P. David, Kornelia J. Skowron, Zamia Siddiqui, Kenneth Booker
Publikováno v:
Mol Cell Endocrinol
The purpose of this review is to highlight recent developments in small molecules and peptides that block the binding of coactivators to steroid receptors. These coactivator binding inhibitors bind at the coregulator binding groove, also known as Act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd2e292e5745b0b27fb444db1f45f1b
https://pubmed.ncbi.nlm.nih.gov/31163202
https://pubmed.ncbi.nlm.nih.gov/31163202
Autor:
Yue-Ting Wang, Katherine Dye, Aleksej Krunic, Haranatha R. Potteti, Chandra R. Tamatam, Kornelia J. Skowron, Benjamin G. Richardson, Phillip R. Lazzara, Atul D. Jain, Brian P. David, Terry W. Moore, Sekhar P. Reddy, Zamia Siddiqui, Ewelina Choma
Activators of Nuclear factor-erythroid 2-related factor 2 (NRF2) could lead to promising therapeutics for prevention and treatment of oxidative stress and inflammatory disorders. Ubiquitination and subsequent degradation of the transcription factor N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f352d70d82530b721f7d392f16e5f065
https://europepmc.org/articles/PMC6190829/
https://europepmc.org/articles/PMC6190829/