Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zakir Tnimov"'
Autor:
Asma Rehman, Shu-Hong Hu, Zakir Tnimov, Andrew E Whitten, Gordon J King, Russell J Jarrott, Suzanne J Norwood, Kirill Alexandrov, Brett M Collins, Michelle P Christie, Jennifer L Martin
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183366 (2017)
Vesicular transport of cellular cargo requires targeted membrane fusion and formation of a SNARE protein complex that draws the two apposing fusing membranes together. Insulin-regulated delivery and fusion of glucose transporter-4 storage vesicles at
Externí odkaz:
https://doaj.org/article/b085b7d07209489292faba0427e15430
Autor:
Chayasith Uttamapinant, Jason W. Chin, Wolfgang H. Schmied, Stephen D. Fried, Christopher D. Rae, Zakir Tnimov
Publikováno v:
Nature. 564:444-448
Orthogonal ribosomes are unnatural ribosomes that are directed towards orthogonal messenger RNAs in Escherichia coli, through an altered version of the 16S ribosomal RNA of the small subunit1. Directed evolution of orthogonal ribosomes has provided a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6411d30ba0b58cd45b009ee439214df7
https://doi.org/10.1038/s41586-018-0773-z
https://doi.org/10.1038/s41586-018-0773-z
Autor:
Naveid A. Ali, Oliver P Skinner, Julie Jurczyluk, Gemma Shay, Zakir Tnimov, Michael J. Rogers, Kirill Alexandrov, Marcia A. Munoz, Nathan J. Pavlos
Publikováno v:
Small GTPases
Bisphosphonate drugs such as zoledronic acid (ZOL), used for the treatment of common bone disorders, target the skeleton and inhibit bone resorption by preventing the prenylation of small GTPases in bone-destroying osteoclasts. Increasing evidence in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9986f7addfff08af4fa4cd060affeebb
https://doi.org/10.1080/21541248.2015.1085485
https://doi.org/10.1080/21541248.2015.1085485
Publikováno v:
Journal of the American Chemical Society. 137:4404-4413
Genetic code expansion is a key objective of synthetic biology and protein engineering. Most efforts in this direction are focused on reassigning termination or decoding quadruplet codons. While the redundancy of genetic code provides a large number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5677e00cce52f8ed8b58e250e534bbf3
https://doi.org/10.1021/ja5131963
https://doi.org/10.1021/ja5131963
Autor:
Michelle P. Christie, Gordon J. King, Asma Rehman, Brett M. Collins, Zakir Tnimov, Jennifer L. Martin, Shu-Hong Hu, Suzanne J. Norwood, Andrew E. Whitten, Kirill Alexandrov, Russell Jarrott
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183366 (2017)
PLoS ONE
PLoS ONE
Vesicular transport of cellular cargo requires targeted membrane fusion and formation of a SNARE protein complex that draws the two apposing fusing membranes together. Insulin-regulated delivery and fusion of glucose transporter-4 storage vesicles at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a1753ba331bdc6f90ae7bbecd07101
http://europepmc.org/articles/PMC5571939?pdf=render
http://europepmc.org/articles/PMC5571939?pdf=render
Autor:
Alun Jones, Thomas Durek, Zakir Tnimov, Sergey Mureev, Zhong Guo, Kirill Alexandrov, Zhenling Cui, Mark E. Polinkovsky
Publikováno v:
ACS synthetic biology. 6(3)
Incorporation of unnatural amino acids (uAAs) via codon reassignment is a powerful approach for introducing novel chemical and biological properties to synthesized polypeptides. However, the site-selective incorporation of multiple uAAs into polypept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598842c91e6b096d35e8feb56120b122
https://pubmed.ncbi.nlm.nih.gov/27966891
https://pubmed.ncbi.nlm.nih.gov/27966891
Autor:
Stuart G. Tangye, Kirill Alexandrov, Anna Simon, Ryan C. Chai, Tri Giang Phan, Jeffrey Chaitow, Marcia A. Munoz, Chelsea N. McMahon, Julie Jurczyluk, Sam Mehr, Dianne E. Campbell, Zakir Tnimov, Davinder Singh-Grewal, Rob J.W. Arts, Julian M.W. Quinn, Angela Sheu, Michael J. Rogers
Publikováno v:
Journal of Allergy and Clinical Immunology, 140, 3, pp. 873-875.e6
Journal of Allergy and Clinical Immunology, 140, 873-875.e6
Journal of Allergy and Clinical Immunology, 140, 873-875.e6
Contains fulltext : 177329.pdf (Publisher’s version ) (Open Access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a975eaf2028ca32441323d0a78cbdde2
https://pubmed.ncbi.nlm.nih.gov/28501347
https://pubmed.ncbi.nlm.nih.gov/28501347
Autor:
Yao-Wen Wu, Zakir Tnimov, Yann Gambin, Uyen T. T. Nguyen, Roger S. Goody, Herbert Waldmann, Brett M. Collins, Daniel Abankwa, Zhong Guo, Kirill Alexandrov, E. Anouk Stigter
Publikováno v:
Journal of Biological Chemistry. 287:26549-26562
Small GTPases of the Rho family regulate cytoskeleton remodeling, cell polarity, and transcription, as well as the cell cycle, in eukaryotic cells. Membrane delivery and recycling of the Rho GTPases is mediated by Rho GDP dissociation inhibitor (RhoG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f27dc372aca4691e19291b77328095
https://doi.org/10.1074/jbc.m112.371294
https://doi.org/10.1074/jbc.m112.371294
Publikováno v:
Biochemical and biophysical research communications. 452(4)
Protein prenylation is a post-translational modification where farnesyl or geranylgeranyl groups are enzymatically attached to a C-terminal cysteine residue. This modification is essential for the activity of small cellular GTPases, as it allows them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c643ef8e30e2b7bd170737512ac7d8f
https://pubmed.ncbi.nlm.nih.gov/25223799
https://pubmed.ncbi.nlm.nih.gov/25223799
Autor:
Govindaraju Thimmaiah, Uyen T. T. Nguyen, Yao-Wen Wu, Roger S. Goody, Zakir Tnimov, Kirill Alexandrov, Debapratim Das, Daniel Abankwa, Herbert Waldmann, Harriet P. Lo
Publikováno v:
Chembiochem : a European journal of chemical biology. 13(5)
Protein modification with isoprenoid lipids affects hundreds of signaling proteins in eukaryotic cells. Modification of isoprenoids with reporter groups is the main approach for the creation of probes for the analysis of protein prenylation in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc971fb96517f1517398b8fd28b97ea
https://pubmed.ncbi.nlm.nih.gov/22351497
https://pubmed.ncbi.nlm.nih.gov/22351497