Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zakary Plautz"'
Autor:
Patricia Rodriguez-Rodriguez, Luis Enrique Arroyo-Garcia, Lechuan Li, Christina Tsagkogianni, Wei Wang, Isabella Salas-Allende, Zakary Plautz, Angel Cedazo-Minguez, Subhash Sinha, Olga Troyanskaya, Marc Flajolet, Vicky Yao, Jean-Pierre Roussarie
SUMMARYNeurons from layer II of the entorhinal cortex (ECII) are the first to accumulate tau protein aggregates and degenerate during prodromal Alzheimer’s disease. Here, we use a data-driven functional genomics approach to model ECII neuronsin sil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0888f740a9e42fe61780d38536b53083
https://doi.org/10.1101/2022.05.14.491965
https://doi.org/10.1101/2022.05.14.491965
Autor:
Patrick R. Hof, Nathaniel Heintz, Olga G. Troyanskaya, Paul Greengard, Zakary Plautz, Christian Albornoz, Alona Barnea-Cramer, Marc Flajolet, Myriam Heiman, Lars Brichta, Victoria Yao, Shirin Kasturia, Eric F. Schmidt, Jean-Pierre Roussarie
A major obstacle to treating Alzheimer’s disease (AD) is our lack of understanding of the molecular mechanisms underlying selective neuronal vulnerability, which is a key characteristic of the disease. Here we present a framework to integrate high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b218b24d86593c287a7633e46a9d7f80
Autor:
Patricia Rodriguez-Rodriguez, Myriam Heiman, Olga G. Troyanskaya, Christian Albornoz, Jennifer M. Rust, Vicky Yao, Ruth Dannenfelser, Paul Greengard, Alona Barnea-Cramer, Jean-Pierre Roussarie, Patrick R. Hof, Eric F. Schmidt, Nathaniel Heintz, Alicja Tadych, Shirin Kasturia, Kara Dolinski, Wei Wang, Lars Brichta, Zakary Plautz, Marc Flajolet, Rose Oughtred
Publikováno v:
Neuron
A major obstacle to treating Alzheimer's disease (AD) is our lack of understanding of the molecular mechanisms underlying selective neuronal vulnerability, a key characteristic of the disease. Here, we present a framework integrating high-quality neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896f8cce9f832294769446347ee635fa
https://doi.org/10.1016/j.neuron.2020.06.010
https://doi.org/10.1016/j.neuron.2020.06.010
