In vivo selection of anti-HIV-1 gene-modified human hematopoietic stem/progenitor cells to enhance engraftment and HIV-1 inhibition

Autor: Guo, Qi, Zhang, Jian, Parikh, Keval, Brinkley, Alexander, Lin, Samantha, Zakarian, Christina, Pernet, Olivier, Shimizu, Saki, Khamaikawin, Wannisa, Hacke, Katrin, Kasahara, Noriyuki, An, Dong Sung

Publikováno v: In Molecular Therapy 7 February 2024 32(2):384-394

In vivoselection of anti-HIV-1 gene-modified human hematopoietic stem/progenitor cells to enhance engraftment and HIV-1 inhibition

Autor: Guo, Qi, Zhang, Jian, Parikh, Keval, Brinkley, Alexander, Lin, Samantha, Zakarian, Christina, Pernet, Olivier, Shimizu, Saki, Khamaikawin, Wannisa, Hacke, Katrin, Kasahara, Noriyuki, An, Dong Sung

Publikováno v: Molecular Therapy; February 2024, Vol. 32 Issue: 2 p384-394, 11p

High-coverage nanopore sequencing of samples from the 1000 Genomes Project to build a comprehensive catalog of human genetic variation.

Autor: Gustafson JA; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA., Gibson SB; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA.; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Damaraju N; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA.; Institute for Public Health Genetics, University of Washington, Seattle, Washington 98195, USA., Zalusky MPG; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Hoekzema K; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Twesigomwe D; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa., Yang L; Pacific Northwest Research Institute, Seattle, Washington 98122, USA., Snead AA; Department of Biology, New York University, New York, New York 10003, USA., Richmond PA; Alamya Health, Baton Rouge, Louisiana 70806, USA., De Coster W; Applied and Translational Neurogenomics Group, VIB Center for Molecular Neurology, VIB, Antwerp 2650, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp 2000, Belgium., Olson ND; Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA., Guarracino A; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.; Human Technopole, Milan 20157, Italy., Li Q; Department of Computer Science, Johns Hopkins University, Baltimore, Maryland 21218, USA., Miller AL; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Goffena J; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Anderson ZB; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Storz SHR; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Ward SA; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Sinha M; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA., Gonzaga-Jauregui C; International Laboratory for Human Genome Research, Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Mexico City 76230, Mexico., Clarke WE; New York Genome Center, New York, New York 10013, USA.; Outlier Informatics Inc., Saskatoon, Saskatchewan S7H 1L4, Canada., Basile AO; New York Genome Center, New York, New York 10013, USA., Corvelo A; New York Genome Center, New York, New York 10013, USA., Reeves C; New York Genome Center, New York, New York 10013, USA., Helland A; New York Genome Center, New York, New York 10013, USA., Musunuri RL; New York Genome Center, New York, New York 10013, USA., Revsine M; Department of Computer Science, Johns Hopkins University, Baltimore, Maryland 21218, USA., Patterson KE; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Paschal CR; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington 98195, USA.; Department of Laboratories, Seattle Children's Hospital, Seattle, Washington 98195, USA., Zakarian C; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Goodwin S; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Jensen TD; Department of Genetics, Stanford University, Stanford, California 94305, USA., Robb E; Department of Computer Science, Stanford University, Stanford, California 94305, USA., McCombie WR; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Sedlazeck FJ; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Computer Science, Rice University, Houston, Texas 77251, USA., Zook JM; Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA., Montgomery SB; Department of Genetics, Stanford University, Stanford, California 94305, USA., Garrison E; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA., Kolmogorov M; Cancer Data Science Laboratory, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA., Schatz MC; Human Technopole, Milan 20157, Italy., McLaughlin RN Jr; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA.; Pacific Northwest Research Institute, Seattle, Washington 98122, USA., Dashnow H; Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA.; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado 80045, USA., Zody MC; International Laboratory for Human Genome Research, Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Mexico City 76230, Mexico., Loose M; Deep Seq, School of Life Sciences, University of Nottingham, Nottingham NG7 2TQ, UK., Jain M; Department of Bioengineering, Northeastern University, Boston, Massachusetts 02115, USA.; Department of Physics, Northeastern University, Boston, Massachusetts 02115, USA.; Khoury College of Computer Sciences, Northeastern University, Boston, Massachusetts 02115, USA., Eichler EE; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, Washington 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, USA., Miller DE; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA; dm1@uw.edu.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington 98195, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, Washington 98195, USA.

Publikováno v: Genome research [Genome Res] 2024 Nov 20; Vol. 34 (11), pp. 2061-2073. Date of Electronic Publication: 2024 Nov 20.

Homotaurine Treatment Enhances CD4 ⁺ and CD8 ⁺ Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice.

Autor: Tian J; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., Dang H; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., O'Laco KA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., Song M; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., Tiu BC; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., Gilles S; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., Zakarian C; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095., Kaufman DL; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095.

Publikováno v: ImmunoHorizons [Immunohorizons] 2019 Oct 21; Vol. 3 (10), pp. 498-510. Date of Electronic Publication: 2019 Oct 21.