Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zakaria Grada"'
Autor:
Zakaria Grada, Meenakshi Hegde, Tiara Byrd, Donald R Shaffer, Alexia Ghazi, Vita S Brawley, Amanda Corder, Kurt Schönfeld, Joachim Koch, Gianpietro Dotti, Helen E Heslop, Stephen Gottschalk, Winfried S Wels, Matthew L Baker, Nabil Ahmed
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Targeted T cells are emerging as effective non-toxic therapies for cancer. Multiple elements, however, contribute to the overall pathogenesis of cancer through both distinct and redundant mechanisms. Hence, targeting multiple cancer-specific markers
Externí odkaz:
https://doaj.org/article/f6109ef91e37425bafdfbf5c6c19c49f
Autor:
Laura J. Tafe, Zakaria Grada, Lubna Azzouz, Konstantinos Linos, Linsheng Zhang, Zoi Evangelou
Publikováno v:
Journal of Cutaneous Pathology. 48:302-308
Primary cutaneous Ewing sarcoma is a very rare entity with less than 100 cases reported in the literature, sharing the same morphological and immunohistochemical characteristics as their osseous counterparts. Herein, to the best of our knowledge, we
Autor:
Mohamed Hassan, Christian R. Gomez, Abdulhadi A. AlAmodi, Fadi Murad, Youssef Haikel, Simeon Santourlidis, Renate U. Wahl, Mohammad Abrar Shareef, Sofie-Yasmin Hassan, Siraj M. El Jamal, Zakaria Grada, Sarah-Lilly Hassan, Mosaad Megahed
Publikováno v:
Oncogene. 39:5468-5478
Melanoma stem cells (MSCs) are characterized by their unique cell surface proteins and aberrant signaling pathways. These stemness properties are either in a causal or consequential relationship to melanoma progression, treatment resistance and recur
Autor:
Zakaria Grada, Doreen N. Palsgrove, Ali Amin, Belkiss Murati-Amador, Andres Matoso, Cynthia L. Jackson, Kara Lombardo
Publikováno v:
Appl Immunohistochem Mol Morphol
Intestinal metaplasia (IM) is a rare finding in urinary bladder specimens. It is unclear whether IM without dysplasia is a precursor of malignancy in the urinary system. We retrospectively selected 9 cases of IM of bladder (1 case harboring high-grad
Autor:
Adolfo Firpo-Betancourt, Mohamed Hassan, Mostafa Fraig, Julie Teruya-Feldstein, Siraj M. El Jamal, Hend A Abulsayen, Zakaria Grada, Barbara Bishop, Ali G Saad
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 27:644-648
Classifying diffuse large B-cell lymphoma (DLBCL) according to the cell-of-origin (COO) was first proposed using gene expression profiling; accordingly, DLBCL is classified into germinal-center B-cell type and activated B-cell type. Immunohistochemis
Autor:
Hend A Abulsayen, Bradley Gibson, Ali G Saad, Siraj M. El Jamal, Myesa Emberesh, Helmi Khadra, Mohamed El Dinali, Mohamed Hassan, Abida Kadi, Hosam Shalaby, Adolfo Firpo-Betancourt, Julie Teruya-Feldstein, Jessica Friedman, Mosaad Megahed, Zakaria Grada, Youssef Haikel, Xinchun Zhou, Mostafa Fraig, He Zhou, Sofie-Yasmin Hassan
Publikováno v:
Laboratory Investigation. 99:539-550
Myocyte enhancer-binding factor 2B (MEF2B) has been implicated as a transcriptional regulator for BCL6. However, details about the interaction between MEF2B and BCL6 during expression, as well as the relationship of MEF2B to the expression of other g
Autor:
Hend A Abulsayen, Ali G Saad, Siraj M. El Jamal, Bridget K. Marcellino, Zakaria Grada, Adolfo Firpo-Betancourt, Mohamed Hassan, Abeer Salama, Julie Teruya-Feldstein
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 28(7)
Publikováno v:
J Immunol
Bispecific T cell engagers have demonstrated clinical efficacy; however, their use can be accompanied by severe toxicity. Mechanistic understanding of these toxicities is limited by a lack of suitable immunocompetent preclinical models. In this study
Abstract 6605: Functional screening of bispecific CAR ectodomains targeting HER2 and GD2 in melanoma
Autor:
Nabil Ahmed, Zakaria Grada, Amanda Wakefield, Ankita Shree, Sujith K. Joseph, Kristen Fousek, Shoba A. Navai, Meenakshi Hegde, Pretty R. Mathew
Publikováno v:
Cancer Research. 80:6605-6605
We describe the development of targeted immunotherapy using a bispecific chimeric antigen receptor (CAR) modified T-cell directed against the tumor associated antigens, human epidermal growth factor receptor 2 (HER2) and the disialoganglioside GD2, s
Autor:
M. Ruhul Quddus, Claire Eklund, Cherie Paquette, C. James Sung, Margaret M. Steinhoff, Zakaria Grada, Cunxian Zhang
Publikováno v:
Acta cytologica. 61(3)
Objective: The 2014 Bethesda System recommends that benign-appearing endometrial cells (BECs) in routine Pap tests should be reported in patients aged ≥45 years. This is a change from previous guidelines to report BECs in women ≥40 years of age.