Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zaiqiao Sun"'
Autor:
Qian Chen, Minhui Pang, Peng Chen, Zihao Zhou, Jun Lei, Boxiao He, Zaiqiao Sun, Chonil Paek, Baowei Jing, Yankang Wu, Shiqi Liu, Yongshun Chen, Lei Yin
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract CRISPR/Cas12a‐based combinational screening has shown remarkable potential for identifying genetic interactions. Here, we describe an innovative method for combinational genetic screening with rapid construction of a dual‐CRISPR RNA (crR
Externí odkaz:
https://doaj.org/article/ef996bcaf008462485874f22f8c6ad37
Autor:
Jialing Fang, Jun Lei, Boxiao He, Yankang Wu, Peng Chen, Zaiqiao Sun, Ning Wu, Yafei Huang, Pengcheng Wei, Lei Yin, Yongshun Chen
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Resident memory T (Trm) cells which are specifically located in non-lymphoid tissues showed distinct phenotypes and functions compared to circulating memory T cells and were vital for the initiation of robust immune response within tissues.
Externí odkaz:
https://doaj.org/article/36d6b28360534518916084c0cdbae9ae
Autor:
Hongjian Wang, Jin Zhou, Jun Lei, Guosheng Mo, Yankang Wu, Huan Liu, Ziyan Pang, Mingkun Du, Zihao Zhou, Chonil Paek, Zaiqiao Sun, Yongshun Chen, Yan Wang, Peng Chen, Lei Yin
Publikováno v:
PLoS Biology, Vol 22, Iss 5, p e3002619 (2024)
The CRISPR-associated endonuclease Cas12a has become a powerful genome-editing tool in biomedical research due to its ease of use and low off-targeting. However, the size of Cas12a severely limits clinical applications such as adeno-associated virus
Externí odkaz:
https://doaj.org/article/9b7a0123beda47698ad978df6865508f
Autor:
Peng Chen, Jin Zhou, Huan Liu, Erchi Zhou, Boxiao He, Yankang Wu, Hongjian Wang, Zaiqiao Sun, Chonil Paek, Jun Lei, Yongshun Chen, Xinghua Zhang, Lei Yin
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002514 (2024)
The clustered regularly interspaced short palindromic repeat (CRISPR)-Cas12a system is a powerful tool in gene editing; however, crRNA-DNA mismatches might induce unwanted cleavage events, especially at the distal end of the PAM. To minimize this lim
Externí odkaz:
https://doaj.org/article/2bf810d189d143e69343ed2a6da8b008
Autor:
Yuman Wang, Zaiqiao Sun, Jieming Ping, Jianlong Tang, Boxiao He, Teding Chang, Qian Zhou, Shijie Yuan, Zhaohui Tang, Xin Li, Yan Lu, Ran He, Ximiao He, Zheng Liu, Lei Yin, Ning Wu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Biosynthesis drives the cell volume increase during T cell activation. However, the contribution of cell volume regulation in TCR signaling during T lymphoblast formation and its underlying mechanisms remain unclear. Here we show that cell v
Externí odkaz:
https://doaj.org/article/22e7eb08470948408bd28fdba7872cfd
Autor:
Yuman Wang, Zaiqiao Sun, Jieming Ping, Jianlong Tang, Boxiao He, Teding Chang, Qian Zhou, Shijie Yuan, Zhaohui Tang, Xin Li, Yan Lu, Ran He, Ximiao He, Zheng Liu, Lei Yin, Ning Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/613556832e0c433388df52f827445570
Publikováno v:
Aquaculture Reports, Vol 25, Iss , Pp 101237- (2022)
Reactive oxygen species (ROS), a group of unstable and highly reactive molecules or free radicals, are productions of molecular oxygen through cell metabolism. In invertebrates, especially in crustaceans, hemolymph plays an extremely important role i
Externí odkaz:
https://doaj.org/article/a393bc49543e41d085df348fdb483c61
Autor:
Fuyuan Yang, Chen Zhou, Ngoc Tuan Tran, Zaiqiao Sun, Jianshao Wu, Hui Ge, Zhen Lu, Chenhui Zhong, Zhihuang Zhu, Qiuhua Yang, Qi Lin
Publikováno v:
FEBS Open Bio, Vol 10, Iss 8, Pp 1587-1600 (2020)
Sea cucumber species are abundant (>1400 species) and widely distributed globally. mtDNA sequencing is frequently used to identify the phylogenetic and evolutionary relationships among species. However, there are no reports on the mitochondrial genom
Externí odkaz:
https://doaj.org/article/a7ebb5bf307b470eb594b158d4e39e0b
Autor:
Ming Zhang, Xinxu Zhang, Ngoc Tuan Tran, Zaiqiao Sun, Xusheng Zhang, Haihui Ye, Yueling Zhang, Hongyu Ma, Jude Juventus Aweya, Shengkang Li
Publikováno v:
mSystems, Vol 6, Iss 5 (2021)
ABSTRACT Molting is a crucial lifelong process in the growth, development, and reproduction of crustaceans. In mud crab (Scylla paramamosain), new exoskeleton, gills, and appendages are formed after a molting, which contributes to a 40 to 90% increas
Externí odkaz:
https://doaj.org/article/f6dc9c5d039c48a781807b1fd565d464
Autor:
Qiuhua Yang, Qi Lin, Jianshao Wu, Ngoc Tuan Tran, Ruifang Huang, Zaiqiao Sun, Zhihuang Zhu, Zhen Lu, Shengkang Li, Chen Zhou
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 4, Iss 2, Pp 2751-2752 (2019)
The complete Holothuria leucospilata mitochondrial genome was determined and analyzed in this work. It had a circular mapping molecular with a total length of 15,904 bp and contained 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and 1 putativ
Externí odkaz:
https://doaj.org/article/aff23fc331f04759a8c4a1618789ea0b