Zobrazeno 1 - 10 of 123 pro vyhledávání: '"Zaiqi, Wang"'
1
Akademický článek
Targeting of focal adhesion kinase enhances the immunogenic cell death of PEGylated liposome doxorubicin to optimize therapeutic responses of immune checkpoint blockade
Autor: Baoyuan Zhang, Ning Li, Jiaming Gao, Yuxi Zhao, Jun Jiang, Shuang Xie, Cuiping Zhang, Qingyu Zhang, Leo Liu, Zaiqi Wang, Dongmei Ji, Lingying Wu, Ruibao Ren
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Backgrounds Immune checkpoint blockade (ICB) is widely considered to exert long-term treatment benefits by activating antitumor immunity. However, many cancer patients show poor clinical responses to ICB due in part to the lack of an immunog
Externí odkaz: https://doaj.org/article/f6130e669747441399b8af4774e9863a
Zobrazit plný text záznamu
2
Akademický článek
Simultaneous inhibition of FAK and ROS1 synergistically repressed triple-negative breast cancer by upregulating p53 signalling
Autor: Ximin Tan, Deguang Kong, Zhuoli Tao, Fangling Cheng, Baoyuan Zhang, Zaiqi Wang, Qi Mei, Chuang Chen, Kongming Wu
Publikováno v: Biomarker Research, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype lacking effective targeted therapies, necessitating innovative treatment approaches. While targeting ROS proto-oncogene 1 (ROS1) with crizotinib has shown
Externí odkaz: https://doaj.org/article/24d48c60eaca471d9e58400153b83d6a
Zobrazit plný text záznamu
3
Akademický článek
Targeting focal adhesion kinase boosts immune response in KRAS/LKB1 co-mutated lung adenocarcinoma via remodeling the tumor microenvironment
Autor: Meng Qiao, Fei Zhou, Xinyu Liu, Tao Jiang, Haowei Wang, Xuefei Li, Chao Zhao, Lei Cheng, Xiaoxia Chen, Shengxiang Ren, Zaiqi Wang, Caicun Zhou
Publikováno v: Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Background KRAS mutation is one of the most common oncogenic drivers in NSCLC, however, the response to immunotherapy is heterogeneous owing to the distinct co-occurring genomic alterations. KRAS/LKB1 co-mutated lung adenocarcinoma displays
Externí odkaz: https://doaj.org/article/c7b5672223364226bbaa66549a19fe3f
Zobrazit plný text záznamu
5
Akademický článek
Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells
Autor: Arsen Osipov, Alex B. Blair, Juliane Liberto, Jianxin Wang, Keyu Li, Brian Herbst, Yao Xu, Shiqi Li, Nan Niu, Rufiaat Rashid, Ding Ding, Yanan Liu, Zaiqi Wang, Christopher L. Wolfgang, Richard A. Burkhart, Daniel Laheru, Lei Zheng
Publikováno v: Cancer Biology & Medicine, Vol 18, Iss 1, Pp 206-214 (2021)
Objective: Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy, due in large part to its resistance to conventional therapies, including radiotherapy (RT). Despite RT exerting a modest antitumor response, it has also been shown to promote
Externí odkaz: https://doaj.org/article/39e6bd391a9843878fe8179f827b11f3
Zobrazit plný text záznamu
6
Akademický článek
Focal Adhesion Kinase (FAK) Inhibition Synergizes with KRAS G12C Inhibitors in Treating Cancer through the Regulation of the FAK–YAP Signaling
Autor: Baoyuan Zhang, Yan Zhang, Jiangwei Zhang, Ping Liu, Bo Jiao, Zaiqi Wang, Ruibao Ren
Publikováno v: Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract KRAS mutation is one of the most prevalent genetic drivers of cancer development, yet KRAS mutations are until very recently considered undruggable. There are ongoing trials of drugs that target the KRAS G12C mutation, yet acquired drug resi
Externí odkaz: https://doaj.org/article/a31d96a1af6c4b72ab49e6db22443a6f
Zobrazit plný text záznamu
7
Akademický článek
A Low-Current and Multi-Channel Chemiresistor Array Sensor Device
Autor: Zaiqi Wang, Guojun Shang, Dong Dinh, Shan Yan, Jin Luo, Aimin Huang, Lefu Yang, Susan Lu, Chuan-Jian Zhong
Publikováno v: Sensors, Vol 22, Iss 7, p 2781 (2022)
This paper describes the design of a low-current, multichannel, handheld electronic device integrated with nanostructured chemiresistor sensor arrays. A key design feature of the electronic circuit board is its low excitation current for achieving op
Externí odkaz: https://doaj.org/article/d4889d2aaa774943bc54758eb28c4d18
Zobrazit plný text záznamu
9
Targeting of Focal Adhesion Kinase enhances the immunogenic cell death of PEGylated liposome doxorubicin to optimize therapeutic responses of immune checkpoint blockade
Autor: Baoyuan Zhang, Ning Li, Jiaming Gao, Yuxi Zhao, Jun Jiang, Shuang Xie, Cuiping Zhang, Qingyu Zhang, Leo Liu, Zaiqi Wang, Dongmei Ji, Linying Wu, Ruibao Ren
Immune checkpoint blockade (ICB) is widely considered to exert long-term treatment benefits by activating antitumor immunity. However, many cancer patients show poor clinical responses to ICB due in part to the lack of immunogenic niche. Focal adhesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f614183eb27e194c078fe5c357444c8c
https://doi.org/10.21203/rs.3.rs-2639424/v1
Zobrazit plný text záznamu
10
Abstract 5821: Synergism of FAK and ROS1 inhibitors in the treatment of CDH1-deficient cancers mediated by FAK-YAP-TRX signaling
Autor: Jiaming Gao, Yunying Yao, Zaiqi Wang, Baoyuan Zhang, Ruibao Ren
Publikováno v: Cancer Research. 83:5821-5821
CDH1 deficiency is common in triple negative breast cancer and diffuse gastric cancer patients, both of which lack effective therapeutics. Although inhibiting ROS1 function results in synthetic lethality in CDH1-deficient cancers, adaptive resistance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e6ea5fd29f6ca95bfbc84bb9ecdedbf
https://doi.org/10.1158/1538-7445.am2023-5821
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje