Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zaineb Javed"'
Autor:
Leonard Frisbie, Catherine Pressimone, Emma Dyer, Roja Baruwal, Geyon Garcia, Claudette St. Croix, Simon Watkins, Michael Calderone, Grace Gorecki, Zaineb Javed, Huda I. Atiya, Nadine Hempel, Alexander Pearson, Lan G. Coffman
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114551- (2024)
Summary: Ovarian cancer is characterized by early metastatic spread. This study demonstrates that carcinoma-associated mesenchymal stromal cells (CA-MSCs) enhance metastasis by increasing tumor cell heterogeneity through mitochondrial donation. CA-MS
Externí odkaz:
https://doaj.org/article/fadc5372690c419fb9d343cb2641fa43
Autor:
Yeon Soo Kim, Priscilla W. Tang, Jaclyn E. Welles, Weihua Pan, Zaineb Javed, Amal Taher Elhaw, Karthikeyan Mythreye, Scot R. Kimball, Nadine Hempel
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102329- (2022)
During metastasis cancer cells must adapt to survive loss of anchorage and evade anoikis. An important pro-survival adaptation is the ability of metastatic tumor cells to increase their antioxidant capacity and restore cellular redox balance. Althoug
Externí odkaz:
https://doaj.org/article/c571266f755244c089d54da4b196f47b
Autor:
Zaineb Javed, Beth Worley, Coryn Stump, Sara Shimko, LaTaijah Crawford, Karthikeyan Mythreye, Nadine Hempel
Publikováno v:
Bio-Protocol, Vol 12, Iss 4 (2022)
Three-dimensional (3D) cell culture models are widely used in tumor studies to more accurately reflect cell-cell interactions and tumor growth conditions in vivo. 3D anchorage-independent spheroids derived by culturing cells in ultra-low attachment (
Externí odkaz:
https://doaj.org/article/4437f036ea924e35bd4c6ec29c1def43
Autor:
Catherine Pressimone, Leonard Frisbie, Emma Dyer, Roja Baruwal, Claudette St. Croix, Simon Watkins, Michael Calderone, Grace Gorecki, Zaineb Javed, Huda I Atiya, Nadine Hempel, Alexander Pearson, Lan Coffman
Ovarian cancer is characterized by early, diffuse metastatic spread with most women presenting with extensive abdominal metastasis at the time of diagnosis. Prior work demonstrated carcinoma-associated mesenchymal stem cells (CA-MSCs) enhance ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afff1cf7fb72b606ef72362253fd668e
https://doi.org/10.1101/2022.09.21.506345
https://doi.org/10.1101/2022.09.21.506345
Autor:
Mehri Monavarian, Amal Taher Elhaw, Priscilla W. Tang, Zaineb Javed, Zainab Shonibare, Carly Bess Scalise, Rebecca Arend, Mohit Kumar Jolly, Mary Kathryn Sewell- Loftin, Nadine Hempel, Karthikeyan Mythreye
Publikováno v:
Seminars in cancer biology. 86(Pt 2)
The ascites ecosystem in ovarian cancer is inhabited by complex cell types and is bathed in an environment rich in cytokines, chemokines, and growth factors that directly and indirectly impact metabolism of cancer cells and tumor associated cells. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b3fc8d36af883442195842707cd998
https://pubmed.ncbi.nlm.nih.gov/35259492
https://pubmed.ncbi.nlm.nih.gov/35259492
Publikováno v:
Cancer Research. 83:A034-A034
Ovarian cancer (OVCA) metastasis occurs through the process of transcoelomic spread, where cells disseminate into the peritoneal fluid and form multi-cellular aggregates (MCA) that mediate Anchorage-Independent (A-I) survival and invasion of the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f53480ab882a67dd8d179d9ba8dc115
https://doi.org/10.1158/1538-7445.metastasis22-a034
https://doi.org/10.1158/1538-7445.metastasis22-a034
Autor:
Zaineb Javed, Dong-Hui Shin, Sierra White, Weihua Pan, Amal Elhaw, Rebecca Phaeton, Vonn Walter, Mohamed Trebak, Nadine Hempel
Publikováno v:
Free Radical Biology and Medicine. 192:103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435631d31bca407ce9723267e9ebdcf7
https://doi.org/10.1016/j.freeradbiomed.2022.10.185
https://doi.org/10.1016/j.freeradbiomed.2022.10.185
Publikováno v:
Free Radical Biology and Medicine. 192:101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b598a343eb8d2824d41357902f011d1d
https://doi.org/10.1016/j.freeradbiomed.2022.10.181
https://doi.org/10.1016/j.freeradbiomed.2022.10.181
Autor:
Zaineb Javed, Karthikeyan Mythreye, Yeon Soo Kim, Nadine Hempel, Priscilla W. Tang, Jaclyn E. Welles, Scot R. Kimball, Amal T. Elhaw
During metastasis, cancer cells must adapt to survive a loss of anchorage and evade anoikis. An important pro-survival adaptation is the ability of metastatic tumor cells to increase their antioxidant capacity and restore cellular redox balance. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac4ff397d52173cbfa2788a88127e19
https://doi.org/10.1101/2021.02.19.432010
https://doi.org/10.1101/2021.02.19.432010
Publikováno v:
Cancer Research. 82:2445-2445
Transcoelomic spread is a major mode of ovarian cancer (OVCA) metastasis, where cells disseminate into the peritoneal ascites fluid, evade anoikis, and form multi-cellular aggregates (MCAs) that mediate anchorage-independent (a-i) survival and invasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d31ab26652439f24bd355eeeb4b6e1ef
https://doi.org/10.1158/1538-7445.am2022-2445
https://doi.org/10.1158/1538-7445.am2022-2445