Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Zainal Ariff Abdul Rahman"'
Autor:
Chuan Wang, Nur Syafinaz Zainal, San Jiun Chai, James Dickie, Chai Phei Gan, Natasha Zulaziz, Bryan Kit Weng Lye, Ruhcha V. Sutavani, Christian H. Ottensmeier, Emma V. King, Mannil Thomas Abraham, Siti Mazlipah binti Ismail, Shin Hin Lau, Thomas George Kallarakkal, Kein Seong Mun, Rosnah binti Zain, Zainal Ariff Abdul Rahman, Gareth J. Thomas, Sok Ching Cheong, Natalia Savelyeva, Kue Peng Lim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
HPV-independent head and neck squamous cell carcinoma (HNSCC) is a common cancer globally. The overall response rate to anti-PD1 checkpoint inhibitors (CPIs) in HNSCC is ~16%. One major factor influencing the effectiveness of CPI is the level of tumo
Externí odkaz:
https://doaj.org/article/4e3b57700cad491b8b3126170d014e2b
Autor:
Yin-Ling Wong, Anand Ramanathan, Kar Mun Yuen, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Zainal Ariff Abdul Rahman, Yeng Chen
Publikováno v:
PeerJ, Vol 9, p e11548 (2021)
Background Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to 2017, especially in South and Southeast Asia. It is often diagnosed at an advanced stage with a poor prognosis. Therefore, early detection of OSCC is essential to
Externí odkaz:
https://doaj.org/article/e0d0253a103d42fcaf17bf7a55c14e5d
Autor:
Nur Syafinaz Zainal, Bernard Kok Bang Lee, Zheng Wei Wong, Iuan Sheau Chin, Pei San Yee, Chai Phei Gan, Kein Seong Mun, Zainal Ariff Abdul Rahman, J. Silvio Gutkind, Vyomesh Patel, Sok Ching Cheong
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 2, Pp 264-275 (2019)
Objective Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including
Externí odkaz:
https://doaj.org/article/0cbed0837b6a4998adfdc5845bbf03bb
Autor:
San Jiun Chai, Sammuel Chee Yong Fong, Chai Phei Gan, Kin Choo Pua, Paul Vey Hong Lim, Shin Hin Lau, Rosnah Binti Zain, Thomas Abraham, Siti Mazlipah Ismail, Zainal Ariff Abdul Rahman, Sathibalan Ponniah, Vyomesh Patel, Sok Ching Cheong, Kue Peng Lim
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 1, Pp 167-178 (2019)
Peptide vaccines derived from tumour-associated antigens have been used as an immunotherapeutic approach to induce specific cytotoxic immune response against tumour. We previously identified that MAGED4B and FJX1 proteins are overexpressed in HNSCC p
Externí odkaz:
https://doaj.org/article/ba11ad8f5d45434c845f6d791e87ae5c
Autor:
Kai Hung Tiong, Jit Kang Chang, Dharini Pathmanathan, Muhammad Zaki Hidayatullah Fadlullah, Pei San Yee, Chee Sun Liew, Zainal Ariff Abdul Rahman, Kheng Ling Beh, Sok Ching Cheong
Publikováno v:
BioTechniques, Vol 65, Iss 6, Pp 322-330 (2018)
We describe a novel automated cell detection and counting software, QuickCount® (QC), designed for rapid quantification of cells. The Bland–Altman plot and intraclass correlation coefficient (ICC) analyses demonstrated strong agreement between cel
Externí odkaz:
https://doaj.org/article/40e512ec0d2d4d248c906a19fdb7b561
Autor:
Vui King Vincent-Chong, Iman Salahshourifar, Kar Mun Woo, Arif Anwar, Rozaimi Razali, Ranganath Gudimella, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Thomas George Kallarakkal, Anand Ramanathan, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Rosnah Binti Zain
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174865 (2017)
BACKGROUND:Cancers of the oral cavity are primarily oral squamous cell carcinomas (OSCCs). Many of the OSCCs present at late stages with an exceptionally poor prognosis. A probable limitation in management of patients with OSCC lies in the insufficie
Externí odkaz:
https://doaj.org/article/6b4773035b5348bd948bc3346e40040e
Autor:
Jesinda P. Kerishnan, Sani Mohammad, Muhamad Shaifunizam Alias, Alan Kang-Wai Mu, Rathna Devi Vaithilingam, Nor Adinar Baharuddin, Syarida H. Safii, Zainal Ariff Abdul Rahman, Yu Nieng Chen, Yeng Chen
Publikováno v:
PeerJ, Vol 4, p e2327 (2016)
Background Periodontitis is one of the most common oral diseases associated with the host’s immune response against periodontopathogenic infection. Failure to accurately diagnose the stage of periodontitis has limited the ability to predict disease
Externí odkaz:
https://doaj.org/article/25e7e41a89644bc2b63245b4685ebd03
Autor:
Yink Heay Kong, Sharifah Nurain Syed Zanaruddin, Shin Hin Lau, Anand Ramanathan, Thomas George Kallarakkal, Vui King Vincent-Chong, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Zainal Ariff Abdul Rahman, Rosnah Binti Zain, Sok Ching Cheong
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134045 (2015)
Oral squamous cell carcinoma (OSCC) is an aggressive disease accounting for more than 260,000 cancer cases diagnosed and 128,000 deaths worldwide. A large majority of cancer deaths result from cancers that have metastasized beyond the primary tumor.
Externí odkaz:
https://doaj.org/article/730f280b845b46368030592a12606e17
Autor:
Vui King Vincent-Chong, Iman Salahshourifar, Lee Peng Karen-Ng, Ming Yhong Siow, Thomas George Kallarakkal, Anand Ramanathan, Yi-Hsin Yang, Goot Heah Khor, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Narayanan Prepageran, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Sok Ching Cheong, Rosnah Binti Zain
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Matrix metalloproteinase 13 (MMP13) plays a central role in the MMP activation cascade that enables degradation of the extracellular matrix and basement membranes, and it is identified as a potential driver in oral carcinogenesis. Therefore, this stu
Externí odkaz:
https://doaj.org/article/aad56cf16fbd427192cf89d8221db4cd
Autor:
Vui King Vincent-Chong, Arif Anwar, Lee Peng Karen-Ng, Sok Ching Cheong, Yi-Hsin Yang, Padmaja Jayaprasad Pradeep, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Zuraiza Mohamad Zaini, Narayanan Prepageran, Thomas George Kallarakkal, Anand Ramanathan, Nur Aaina Binti Mohd Mohayadi, Nurul Shielawati Binti Mohamed Rosli, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Rosnah Binti Zain
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54705 (2013)
Despite the advances in diagnosis and treatment of oral squamous cell carcinoma (OSCC), mortality and morbidity rates have not improved over the past decade. A major drawback in diagnosis and treatment of OSCC is the lack of knowledge relating to how
Externí odkaz:
https://doaj.org/article/b556b6e3499243d299dc70b8f4baae2e