Výsledky vyhledávání - "Zainab M. Khoder"

Akademický článek

Synthesis, Anti-Cancer Activity, Cell Cycle Arrest, Apoptosis Induction, and Docking Study of Fused Benzo[h]chromeno[2,3-d]pyrimidine on Human Breast Cancer Cell Line MCF-7

Autor: Zainab M. Khoder, Mosaad S. Mohamed, Samir M. Awad, Amal F. Gharib, Omnia Aly, Marwa Abd El-Fattah Khodair, Samar S. Fatahala, Rania H. Abd El-Hameed

Publikováno v: Molecules, Vol 29, Iss 19, p 4697 (2024)

Breast cancer is the predominant form of cancer among women and ranks as the second most prevalent cancer globally, affecting both developed and less developed countries. Presently, accessible cancer treatment methods either employ recently created,

Externí odkaz: https://doaj.org/article/885728ae13ad40c68a2cc42ea619e13e

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Akademický článek

Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents

Autor: Amira I. Sayed, Yara E. Mansour, Mohamed A. Ali, Omnia Aly, Zainab M. Khoder, Ahmed M. Said, Samar S. Fatahala, Rania H. Abd El-Hameed

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1821-1837 (2022)

Current medical approaches to control the Covid-19 pandemic are either to directly target the SARS-CoV-2 via innovate a defined drug and a safe vaccine or indirectly target the medical complications of the virus. One of the indirect strategies for fi

Externí odkaz: https://doaj.org/article/8fc3dd193dfb44319d848cba61ab5034

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Akademický článek

Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents

Autor: Rania Helmy Abd El-Hameed, Amira Ibrahim Sayed, Shima Mahmoud Ali, Mohamed A. Mosa, Zainab M. Khoder, Samar Said Fatahala

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2183-2198 (2021)

Pyrroles and its fused forms possess antimicrobial activities, they can easily interact with biomolecules of living systems. A series of substituted pyrroles, and its fused pyrimidines and triazines forms have been synthesised, all newly synthesised

Externí odkaz: https://doaj.org/article/f1c9b4360a3c4baead207ed8f7344c44

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Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents

Autor: Amira Ibrahim Sayed, Shima Mahmoud Ali, Rania H. Abd El-Hameed, Mohamed A. Mosa, Zainab M. Khoder, Samar S. Fatahala

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2183-2198 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31baad220e02eae06f8fdc437b065d4

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Stereoselective and Regioselective Synthesis of Heterocycles via Copper-Catalyzed Additions of Amine Derivatives and Alcohols to Alkenes

Autor: Zainab M. Khoder, Sherry R. Chemler, Shuklendu D. Karyakarte

Publikováno v: The Journal of Organic Chemistry. 82:11311-11325

This Perspective describes the development of a family of copper(II)-catalyzed alkene difunctionalization reactions that enable stereoselective addition of amine derivatives and alcohols onto pendant unactivated alkenes to provide a range of valuable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9870c6efd68d420f81f1e3a459f97b4f
https://doi.org/10.1021/acs.joc.7b02072

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Stereoselective Synthesis of Isoxazolidines via Copper-Catalyzed Alkene Diamination

Autor: Christina Wong, Sherry R. Chemler, Zainab M. Khoder

Publikováno v: ACS Catalysis. 7:4775-4779

A convenient copper-catalyzed intramolecular/intermolecular alkene diamination reaction to synthesize 3-aminomethyl-functionalized isoxazolidines under mild reaction conditions and with generally high levels of diastereoselectivity was achieved. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322ec1247c0a4a1cd679e3573b132143
https://doi.org/10.1021/acscatal.7b01362

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Saturated oxygen and nitrogen heterocycles

Autor: Jonathan M, Shikora, Chanchamnan, Um, Zainab M, Khoder, Sherry R, Chemler

Publikováno v: Chemical Science

The oxidative coupling of alkyltrifluoroborates with heteroatom-tethered vinylarenes leads to a broad range of saturated oxygen and nitrogen heterocycles.
Saturated heterocycles are important components of many bioactive compounds. The method di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2aadc10e984b2b8fcf7ac5559d60c749
https://pubmed.ncbi.nlm.nih.gov/32055311

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ChemInform Abstract: Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters

Autor: Sherry R. Chemler, Zainab M. Khoder, Ilyas A. Berhane, Barbara J. Casavant

Publikováno v: ChemInform. 47

A unique method to affect intramolecular aminooxygenation and dioxygenation of allenols and allenylsulfonamides is described. These operationally simple reactions occur under neutral or basic conditions where copper(II) carboxylates serve as reaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4bc11364384b2563e281337b432bbbdb
https://doi.org/10.1002/chin.201619026

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Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters

Autor: Ilyas A. Berhane, Barbara J. Casavant, Sherry R. Chemler, Zainab M. Khoder

Publikováno v: Organic letters. 17(24)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357fc3dd79815ef7e26ec90117462a2a
https://pubmed.ncbi.nlm.nih.gov/26624861

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