Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zainab Al Shuhaib"'
Publikováno v:
Mediterranean Journal of Chemistry, Vol 9, Iss 4, Pp 305-310 (2019)
The present study established the efficient separate synthesis of four unique 1, 2, 3-triazole derivatives (M1, M2, M3, M4) via conducting 1,3-dipolar cycloaddition of N-((4-azidophenyl) sulfonyl) acetamide, with substituted N-phenylmaleimide. FTIR,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de19c2795a3ed5087e8b0f582acefbcb
http://www.medjchem.com/index.php/medjchem/article/view/1021
http://www.medjchem.com/index.php/medjchem/article/view/1021
Autor:
Barbara Bartholomew, Iestyn Jones, Patrick J. Murphy, Robert J. Nash, Graham J. Tizzard, Andrew J. Thornhill, Simon J. Coles, Daniel M. Evans, Richard Rowles, Marcel Arndt, Yones K. Sadaghiani, Jackie Hollinshead, Vera Leitmann, Zainab Al Shuhaib, Mark Dennis, Dion Roberts
Publikováno v:
Tetrahedron. 73:845-852
The cyclisation of N-allyl- and N-homoallylguanidines using DMDO leading to the formation of novel 5- and 6-membered guanidine heterocycles is reported. Several of the products formed displayed weak inhibition of glycosidase enzymes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35785273feb841235acb95104e1a09cb
https://doi.org/10.1016/j.tet.2016.12.065
https://doi.org/10.1016/j.tet.2016.12.065
Autor:
Mark Dennis, Richard Rowles, Iestyn Jones, Deiniol Davies, Paul Hancock, Kristina Kähm, Patrick J. Murphy, Robert J. Nash, Matthew D. Fletcher, Daniel M. Evans, Jackie Hollinshead, Zainab Al Shuhaib, Herjan Franken, David M Potter
Publikováno v:
Tetrahedron. 70:4412-4419
The cyclisation of mono-protected and bis-protected guanidines 8a–j under standard iodocyclisation conditions (I2/K2CO3) gave the guanidine heterocycles 9–25 via either a direct cyclisation or by a cyclisation/ring-contraction process, which coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de813cb7a9ebe40ae59d436c22fb058d
https://doi.org/10.1016/j.tet.2014.03.087
https://doi.org/10.1016/j.tet.2014.03.087
Autor:
Bruno J. Neves, Ligia F. Martins, Andrew J. Thornhill, Harri Lloyd Williams, Andre G. Tempone, Hisham S. Fituri, Zainab Al Shuhaib, John P. Leyland, Philip M. Harper, Andrew Howard-Jones, Patrick J. Murphy, Samanta Etel Treiger Borborema, Claire Martin, Juliana T. Mesquita, Dafydd A. Thomas, Daniel M. Evans, Erika G. Pinto, Carolina Horta Andrade, Thais A. Costa-Silva, Terence D. Roberts, Stephen A. Vale, Gregory P. Black, Elliot L. Bennett, Larry E. Overman, Roberto G. S. Berlinck, Andres J. Galisteo Junior
Publikováno v:
Martins, Ligia F; Mesquita, Juliana T; Pinto, Erika G; Costa-Silva, Thais A; Borborema, Samanta ET; Galisteo Junior, Andres J; et al.(2016). Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes.. Journal of natural products, 79(9), 2202-2210. doi: 10.1021/acs.jnatprod.6b00256. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/18m534gk
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Synthetic analogues of marine sponge guanidine alkaloids showed in vitro antiparasitic activity against Leishmania (L.) infantum and Trypanosoma cruzi. Guanidines 10 and 11 presented the highest selectivity index when tested against Leishmania. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397cf85b7ce2142139731fd064271987
https://pubmed.ncbi.nlm.nih.gov/27586460
https://pubmed.ncbi.nlm.nih.gov/27586460
Autor:
Patrick J. Murphy, Zainab Al-Shuhaib, Elina Dörksen, Robert J. Nash, Lawrence Coghlan, Iestyn Jones, James M. Page, Henning Böckemeier
Publikováno v:
Tetrahedron Letters. 54:6716-6718
The Pd-mediated π-allyl cyclisation of bis-Cbz- and bis-Boc - protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4e97940f166d31b81803d68ebd61f7
https://doi.org/10.1016/j.tetlet.2013.09.093
https://doi.org/10.1016/j.tetlet.2013.09.093
Autor:
Patrick J. Murphy, Zainab Al-Shuhaib, Elina Doerksen, James M. Page, Lawrence Coghlan, Robert Nash, Iestyn Jones, Henning Boeckemeier
Publikováno v:
ChemInform. 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d333c136adbf7900251f51ab3b7f7121
https://doi.org/10.1002/chin.201415030
https://doi.org/10.1002/chin.201415030