Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Zaiming Luo"'
Autor:
En Yin Lai, Christopher S. Wilcox, William J. Welch, Kathy K. Griendling, Zaiming Luo, Lingli Li, Margarida Mendonca, Glenn Solis, Anton Wellstein
Publikováno v:
Hypertension. 72:1208-1216
High salt, Ang II (angiotensin II), and reactive oxygen species enhance progression of chronic kidney disease. We tested the hypothesis that a high salt intake generates specific reactive oxygen species to enhance Ang II contractions of afferent arte
Autor:
Kathy K. Griendling, William J. Welch, Anton Wellsten, W. Robert Taylor, Christopher S. Wilcox, En Yin Lai, Lingli Li, Pedro A. Jose, Glenn Solis, Zaiming Luo
Publikováno v:
Kidney International. 92:625-633
Myogenic contractions protect kidneys from barotrauma but are impaired in chronic kidney disease (CKD). Since myogenic contractions are enhanced by superoxide but impaired by hydrogen peroxide, we tested the hypothesis that they are counterregulated
Autor:
Margarida Mendonca, Anton Wellstein, Christopher S. Wilcox, Zaiming Luo, En Yin Lai, Lingli Li, William J. Welch, Kathy K. Griendling, Glenn Solis
Publikováno v:
Hypertension. 72
High salt intake, angiotensin II (Ang II), and reactive oxygen species (ROS) enhance progression of chronic kidney disease (CKD). We reported that myogenic contractions of renal afferent arterioles (RAAs) were enhanced by superoxide (O 2 ·- ) genera
Autor:
Robin L. Davisson, Christopher S. Wilcox, En Yin Lai, Lingli Li, William J. Welch, Zaiming Luo
Publikováno v:
Hypertension. 72
The brain depends on a continuous supply of blood for its oxygenation, whereas the kidney is over-perfused for its metabolic needs in order to provide sufficient plasma to form a glomerular filtrate. Thus, the brain requires resilience to vasoconstri
Autor:
James Tomlinson, Tracy Bell, Zaiming Luo, Christopher S. Wilcox, William J. Welch, Magali Araujo, James Leiper
Nitric oxide prevents hypertension yet enhances proximal tubule Na+reabsorption. Nitric oxide synthase is inhibited by asymmetric dimethylarginine (ADMA) that is metabolized by dimethylarginine dimethylaminohydrolase (DDAH) whose type 1 isoform is ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d18b1dbf3dcd7bc50ce8e98b4187fe3
https://eprints.gla.ac.uk/196723/1/196723.pdf
https://eprints.gla.ac.uk/196723/1/196723.pdf
Autor:
James Tomlinson, Anton Wellstein, Cheng Wang, Dan Wang, Christopher S. Wilcox, James Leiper, Zaiming Luo, Gabriella Carter, Pedro A. Jose, William J. Welch
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 314(3)
Nuclear factor erythyroid factor 2 (Nrf2) transcribes genes in cultured endothelial cells that reduce reactive oxygen species (ROS) and generate nitric oxide (NO) or metabolize asymmetric dimethylarginine (ADMA), which inhibits NO synthase (NOS). The
Publikováno v:
Hypertension. 66:550-556
Because superoxide dismutase (SOD) knockout enhances arteriolar remodeling and contractility, we hypothesized that remodeling enhances contractility. In the isolated and perfused renal afferent arterioles from SOD wild type (+/+) and gene-deleted mic
Autor:
Pedro A. Jose, Christopher S. Wilcox, Dan Wang, Donald E. Kohan, Anton Wellstein, Zaiming Luo, Cheng Wang, William J. Welch
Publikováno v:
Hypertension. 65:1055-1063
Cardiovascular disease is frequent in chronic kidney disease and has been related to angiotensin II, endothelin-1 (ET-1), thromboxane A 2 , and reactive oxygen species (ROS). Because activation of thromboxane prostanoid receptors (TP-Rs) can generate
Publikováno v:
Hypertension. 65:896-902
Dimethylarginine dimethylaminohydrolase (DDAH) degrades asymmetric dimethylarginine, which inhibits nitric oxide (NO) synthase (NOS). Nuclear factor erythroid 2–related factor 2 (Nrf2) is a transcriptional factor that binds to antioxidant response
Publikováno v:
Hypertension. 70
Endothelial cells (ECs) lose their endothelial specification and gain mesenchymal cell features during endothelial-mesenchymal transition (EndMT). Post-developmental EndMT disrupts EC homeostasis, leading to vascular dysfunction. We found that affere