Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zaikuan Yu"'
Dissertation/ Thesis
Autor:
Zaikuan Yu (6983726)
Mass spectrometry (MS) has become one of the most powerful and versatile tools for chemical analysis due to its ultra-high sensitivity, high throughput, ease of automation, and the large amount of information obtained. Nowadays, MS is extensively use
Autor:
Hanyu Zhu, Fabio H. Ribeiro, Lan Xu, W. Nicholas Delgass, John C. Degenstein, Rakesh Agrawal, Mckay W Easton, Priya Murria, Hilkka I. Kenttämaa, Zaikuan Yu
Publikováno v:
The Journal of Physical Chemistry A. 123:9149-9157
A commercial fast pyrolysis probe coupled with a high-resolution tandem mass spectrometer was employed to identify the initial reactions and products of fast pyrolysis of xylobiose and xylotriose, model compounds of xylans. Fragmentation of the reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ac5d2919defab2c6eb2905598ffc55
https://doi.org/10.1021/acs.jpca.9b04438
https://doi.org/10.1021/acs.jpca.9b04438
Autor:
Hilkka I. Kenttämaa, Edouard Niyonsaba, John Kong, Leah F. Easterling, Mckay W Easton, Zhoupeng Zhang, Harry R. Chobanian, Gozdem Kilaz, Huaming Sheng, Erlu Feng, Nicholas R. Deprez, Zaikuan Yu, Jacob Milton, Mark T. Cancilla
Publikováno v:
Analytical Chemistry. 91:11388-11396
Glucuronidation, a common phase II biotransformation reaction, is one of the major in vitro and in vivo metabolism pathways of xenobiotics. In this process, glucuronic acid is conjugated to a drug ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26900fb10ea9b3dbe41b0cf02ebfb6b
https://doi.org/10.1021/acs.analchem.9b02717
https://doi.org/10.1021/acs.analchem.9b02717
Autor:
Leah F. Easterling, Mckay W Easton, Hilkka I. Kenttämaa, Zhoupeng Zhang, John Kong, Judy Liu, Zaikuan Yu, Jacob Milton, Huaming Sheng, Edouard Niyonsaba
Publikováno v:
Organic Process Research & Development. 23:1159-1166
The levels of potentially mutagenic impurities (PMIs) in active pharmaceutical ingredients are highly regulated and must be below a critical safety threshold. One class of PMIs is primary carbamates, which are formed during drug manufacturing and for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63f8a3d3f612292174f715b77520a33c
https://doi.org/10.1021/acs.oprd.9b00080
https://doi.org/10.1021/acs.oprd.9b00080
Autor:
Edouard, Niyonsaba, McKay W, Easton, Erlu, Feng, Zaikuan, Yu, Zhoupeng, Zhang, Huaming, Sheng, John, Kong, Leah F, Easterling, Jacob, Milton, Harry R, Chobanian, Nicholas R, Deprez, Mark T, Cancilla, Gozdem, Kilaz, Hilkka I, Kenttämaa
Publikováno v:
Analytical chemistry. 91(17)
Glucuronidation, a common phase II biotransformation reaction, is one of the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9923c699e83689516048233c91e25074
https://pubmed.ncbi.nlm.nih.gov/31381321
https://pubmed.ncbi.nlm.nih.gov/31381321
Autor:
Zaikuan Yu
Mass spectrometry (MS) has become one of the most powerful and versatile tools for chemical analysis due to its ultra-high sensitivity, high throughput, ease of automation, and the large amount of information obtained. Nowadays, MS is extensively use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dca4a23469016e08cba8ed36e61ae1d
Autor:
Mckay W Easton, Hilkka I. Kenttämaa, John Kong, Edouard Niyonsaba, Zhoupeng Zhang, Arun K. Ghosh, Zaikuan Yu, Tiffany M. Jarrell, Huaming Sheng, Xin Ma, Ravikiran Yerabolu
Publikováno v:
Analytical chemistry. 90(15)
Isomeric O- and N-glucuronides are common drug metabolites produced in phase II of drug metabolism. Distinguishing these isomers by using common analytical techniques has proven challenging. A tandem mass spectrometric method based on gas-phase ion/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1332b271ee811ad94bdce4947eae13d
https://pubmed.ncbi.nlm.nih.gov/29984992
https://pubmed.ncbi.nlm.nih.gov/29984992
Autor:
Jingyao Qu, Jing Song, Zhigang Wu, Yuxi Guo, Hailiang Zhu, Lei Li, Peng George Wang, Xinyuan Zhao, Cheng Ma, Xu Li, Zaikuan Yu, Jeffrey Meisner
Publikováno v:
Analytical Chemistry. 87:7833-7839
N-glycosylation is one of the most prevalence protein post-translational modifications (PTM) which is involved in several biological processes. Alternation of N-glycosylation is associated with cellular malfunction and development of disease. Thus, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11999e1fc0a8110af32a9f3129b30753
https://doi.org/10.1021/acs.analchem.5b02177
https://doi.org/10.1021/acs.analchem.5b02177
Autor:
Lianwen Zhang, Jiansong Cheng, Wanyi Guan, Peng George Wang, Shanshan Li, Lei Li, Hailiang Zhu, Kuan Jiang, Cheng Ma, He Zhu, Yanyi Chen, Zhigang Wu, Jing Li, Zaikuan Yu, Yunpeng Liu
Publikováno v:
Bioconjugate chemistry. 27(9)
Here we report a facile and efficient method for site-directed glycosylation of peptide/protein. The method contains two sequential steps: generation of a GlcNAc-O-peptide/protein, and subsequent ligation of a eukaryotic N-glycan to the GlcNAc moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634ac4c2180bb2f9e5b87ef537f35648
https://pubmed.ncbi.nlm.nih.gov/27529638
https://pubmed.ncbi.nlm.nih.gov/27529638
Autor:
Tiehai Li, Na Wei, Mohui Wei, Jian Liu, Baolin Wu, Vireak Thon, Yongmei Xu, Xi Chen, Zaikuan Yu, Peng George Wang
Publikováno v:
Organic & biomolecular chemistry, vol 13, iss 18
A biotinylated heparosan hexasaccharide was synthesized using a one-pot multi-enzyme strategy, in situ activation and transfer of N-trifluoroacetylglucosamine (GlcNTFA) to a heparin backbone significantly improved the synthetic efficiency. The biotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef66fb138afd5e0637c226f5990b7464