Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zaid W. El‐Husseini"'
Autor:
Zaid W. El-Husseini, Dmitry Khalenkow, Andy Lan, Thys van der Molen, Chris Brightling, Alberto Papi, Klaus F. Rabe, Salman Siddiqui, Dave Singh, Monica Kraft, Bianca Beghe, Maarten van den Berge, Djoke van Gosliga, Martijn C. Nawijn, Stefan Rose-John, Gerard H. Koppelman, Reinoud Gosens
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Asthma is stratified into type 2-high and type 2-low inflammatory phenotypes. Limited success has been achieved in developing drugs that target type 2-low inflammation. Previous studies have linked IL-6 signaling to severe asthma.
Externí odkaz:
https://doaj.org/article/e4d93162eadc447d86daca4b0d26e0df
Autor:
Zaid W. El‐Husseini, Judith M. Vonk, Maarten van denBerge, Reinoud Gosens, Gerard H. Koppelman
Publikováno v:
Clinical and Translational Allergy, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction Asthma is a complex, polygenic, heterogenous inflammatory disease. Recently, we generated a list of 128 independent single nucleotide polymorphisms (SNPs) associated with asthma in genome‐wide association studies. However, it
Externí odkaz:
https://doaj.org/article/0e8cd52efa0443b49dbf35e43a6d9863
Publikováno v:
The Lancet Respiratory Medicine
Asthma is an inflammatory airway disease that is estimated to affect 339 million people globally. The symptoms of about 5-10% of patients with asthma are not adequately controlled with current therapy, and little success has been achieved in developi