Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zai-Hua Zhao"'
Autor:
Yang Liu, Zai-Hua Zhao, Tao Wang, Jin-Yu Yao, Wen-Qing Wei, Li-Hong Su, Shuang-Shuang Tan, Zi-Xuan Liu, Han Song, Jing-Yuan Chen, Wei Zheng, Wen-Jing Luo, Gang Zheng
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 256, Iss , Pp 114861- (2023)
The brain barrier is an important structure for metal ion homeostasis. According to studies, lead (Pb) exposure disrupts the transportation of copper (Cu) through the brain barrier, which may cause impairment of the nervous system; however, the speci
Externí odkaz:
https://doaj.org/article/be4eea3df78147878ec1ed18f50478f4
Autor:
Zai-Hua Zhao, Ke-Jun Du, Tao Wang, Ji-Ye Wang, Zi-Peng Cao, Xiao-Ming Chen, Han Song, Gang Zheng, Xue-Feng Shen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Lead (Pb) can cause a significant neurotoxicity in both adults and children, leading to the impairment to brain function. Pb exposure plays a key role in the impairment of learning and memory through synaptic neurotoxicity, resulting in the cognitive
Externí odkaz:
https://doaj.org/article/dd18e45650f84dfba554f0132fd3d61c
Autor:
Zai-Hua Zhao, Gang Zheng, Tao Wang, Ke-jun Du, Xiao Han, Wen-Jing Luo, Xue-Feng Shen, Jing-Yuan Chen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Lead (Pb) is known to impair children’s cognitive function. It has been previously shown that developmental Pb exposure alters dendritic spine formation in hippocampal pyramidal neurons. However, the underlying mechanism has not yet been d
Externí odkaz:
https://doaj.org/article/77203239fd184041ac68f8ae0b0aae3d
Autor:
Zai-Hua Zhao, Shi Zhao, Ting Li, Gong-Ping Liu, Xue-Feng Shen, Jian-Zhi Wang, Hua-Li Wan, Qun Wang, Bing-Ge Zhang, Qian Liu, Xiao-Yue Hong
Publikováno v:
Theranostics
Background: Abnormal tau accumulation in the brain has a positively correlation with neurodegeneration and memory deterioration, but the mechanism underlying tau-associated synaptic and cognitive impairments remains unclear. Our previous work has fou
Autor:
Han Song, Gang Zheng, Xue-Feng Shen, Zai-Hua Zhao, Yang Liu, Ying-Ying Liu, Jun-Jun Kang, Jing-Yuan Chen, Wen-Jing Luo
Publikováno v:
Biophysics Reports. 6:211-221
Understanding the precise intracellular localization of lead (Pb) is a key in deciphering processes in Pb-induced toxicology. However, it is a great challenge to trace Pbin vitro, especially in cultured cells. We aimed to find an innovative and effic
Autor:
Hua-Li Wan, Xiao-Yue Hong, Zai-Hua Zhao, Ting Li, Bing-Ge Zhang, Qian Liu, Qun Wang, Shi Zhao, Jian-Zhi Wang, Xue-Feng Shen, Gong-Ping Liu
Publikováno v:
Theranostics; 2021, Vol. 11 Issue 11, p5511-5524, 14p
Autor:
Zai Hua Zhao, Han Song, Xue Feng Shen, Jing Yuan Chen, Michael Aschner, Yang Liu, Wen Jing Luo, Gang Zheng
Publikováno v:
Toxicology and applied pharmacology. 297
As the structural basis of blood-cerebrospinal fluid barrier (BCB), epithelial cells in the choroid plexus (CP) are targets for lead (Pb). Pb is known to accumulate in the CP; however, the mechanism of Pb uptake in the choroidal epithelial cells rema