Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zahraa Abdul Sater"'
Autor:
Richard N. Bergman, Mary Walter, Peter Herscovitch, Yaron Rotman, Joyce D. Linderman, Fink Ya, Alison S. Baskin, Marilyn Ader, James W. Johnson, Chen Ky, Zahraa Abdul Sater, Robert J. Brychta, Francesca Piccinini, Suzanne McGehee, Laura A. Fletcher, Norman B. Javitt, William Dieckmann, Cai H, Corina Millo, Devika Kapuria, ero C, Peter Walter, Thomas M. Cassimatis, Alana E O'Mara, Brooks P. Leitner, Kelsey N, Aaron M. Cypess
Publikováno v:
J Clin Invest
BACKGROUND: Mirabegron is a β3-adrenergic receptor (β3-AR) agonist approved only for the treatment of overactive bladder. Encouraging preclinical results suggest that β3-AR agonists could also improve obesity-related metabolic disease by increasin
Autor:
Laura A. Fletcher, Hannah J. Lea, Thomas M. Cassimatis, Kong Y. Chen, Kenneth Y. Zhu, Joyce D. Linderman, Robert J. Brychta, Alana E O'Mara, Aaron M. Cypess, Nikita Sanjay Israni, Zahraa Abdul Sater, James W. Johnson, Cheryl Cero
Publikováno v:
Journal of Biological Chemistry. 295:1926-1942
The current obesity pandemic results from a physiological imbalance in which energy intake chronically exceeds energy expenditure (EE), and prevention and treatment strategies remain generally ineffective. Approaches designed to increase EE have been
Autor:
Sriram Gubbi, Melissa K Gonzales, David Taïeb, Zahraa Abdul Sater, Ahmed M. Gharib, Mayank Patel, Adel Mandl, Ali Cahid Civelek, Ahmed Hamimi, Sungyoung Auh, Abhishek Jha, Karel Pacak, Alana E O'Mara, Aaron M. Cypess, Iris R Hartley
Publikováno v:
J Clin Endocrinol Metab
Context Pheochromocytomas/paragangliomas (PPGLs) are neuroendocrine tumors that can secrete norepinephrine (NE). Brown adipose tissue (BAT) activation is mediated through the action of NE on β-adrenoceptors (β-ARs). In some malignancies, BAT activa
Publikováno v:
Diabetes. 70
Cushing Syndrome (CS) is characterized by cortisol excess that leads to impaired glucose tolerance and obesity. CT imaging shows 20% of CS patients have nonalcoholic steatohepatitis (NASH). While the gold standard diagnostic test for NASH is liver bi
Autor:
Steven J. Soldin, Hilal Sekizkardes, Zahraa Abdul Sater, Sungyoung Auh, Tzu-Chun Lin, Elaine Cochran, Robert J. Brychta, Sergiy V. Kushchayev, Yevgeniya S Kushchayeva, William Dieckmann, Marissa Lightbourne, Megan Startzell, Aaron M. Cypess, Corina Millo, Monica C. Skarulis, Rebecca J. Brown
Publikováno v:
J Clin Endocrinol Metab
Context Patients with mutations of the insulin receptor gene (INSR) have extreme insulin resistance and are at risk for early morbidity and mortality from diabetes complications. A case report suggested that thyroid hormone could improve glycemia in
Autor:
Jorge A. Carrasquillo, Zahraa Abdul Sater, Pavel Nockel, Abhishek Jha, Markku Miettinen, Alexander Ling, Sheila K Mangelen, Melissa K Gonzales, Mustapha El Lakis, Karel Pacak, Adel Mandl, Karen T. Adams, Osorio Abath Neto
Publikováno v:
Nuclear Medicine and Molecular Imaging. 53:144-147
A 36-year-old male patient initially presented with hypertension, tinnitus, bilateral carotid masses, a right jugular foramen, and a periaortic arch mass with an elevated plasma dopamine level but an otherwise normal biochemical profile. On surveilla
Autor:
Maria J. Merino, Dhaval Patel, Sudheer Kumar Gara, Naris Nilubol, Andreas Giannakou, Douglas Wiseman, Pavel Nockel, Yevgeniya Y. Kushchayeva, Electron Kebebew, Joanna Klubo-Gwiezdzinska, Mustapha El Lakis, Zahraa Abdul Sater
Publikováno v:
Surgery. 165:50-57
BACKGROUND: There are conflicting reports on whether familial nonmedullary thyroid cancer is more aggressive than sporadic nonmedullary thyroid cancer. Our aim was to determine if the clinical and pathologic characteristics of familial nonmedullary t
Autor:
Kong Y. Chen, Ahmed Hamimi, Zahraa Abdul Sater, Jatin R. Matta, Janet F. Eary, Ahmed M. Gharib, Ronald Ouwerkerk, Khaled Z. Abd-Elmoniem, Aaron M. Cypess
Publikováno v:
Radiology. 299(2)
Background Activation of brown adipose tissue (BAT) in rodents increases lipolysis in white adipose tissue (WAT) and improves glucose tolerance. Adult humans can have metabolically active BAT. Implications for diabetes and obesity in humans require a
Autor:
Zahraa Abdul Sater, Iris R Hartley, Smita Jha, Katherine A Araque, Lynnette K. Nieman, Raven McGlotten, Mustapha El Lakis
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 103:2811-2814
Context Patients taking exogenous glucocorticoids are at risk for gastrointestinal (GI) complications, including peptic ulcer disease with perforation and gastric bleeding. However, little is known about the GI comorbidity in patients with endogenous
Autor:
James Welch, Robert T. Jensen, Vaishali I. Parekh, Jenny E Blau, Sunita K. Agarwal, William F. Simonds, Adel Mandl, Roxanne Merkel, Lee S. Weinstein, Zahraa Abdul Sater, Jaydira Del Rivero, David S. Schrump, Craig Cochran, Gayathri Veeraraghavan
Publikováno v:
Journal of the Endocrine Society
Patients with the multiple endocrine neoplasia 1 (MEN1) syndrome develop various tumors during their lifetime. One of the rare manifestations observed in MEN1 patients is thymic neuroendocrine tumor (Th-NET) or thymic carcinoid, which is a major caus