Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Zahra Rahman"'
1
Akademický článek
Immune-Related Adverse Events in PD-1 Treated Melanoma and Impact Upon Anti-Tumor Efficacy: A Real World Analysis
Autor: Melissa L. Bastacky, Hong Wang, Dylan Fortman, Zahra Rahman, Gerard P. Mascara, Timothy Brenner, Yana G. Najjar, Jason J. Luke, John M. Kirkwood, Hassane M. Zarour, Diwakar Davar
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
BackgroundAnti-PD-1 immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of melanoma by producing durable long-term responses in a subset of patients. ICI-treated patients develop unique toxicities - immune related adverse event
Externí odkaz: https://doaj.org/article/bb1201d2dc294e4d8fa1c2c7bb33a26c
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2
Akademický článek
Neoadjuvant ipilimumab (3 mg/kg or 10 mg/kg) and high dose IFN-α2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire
Autor: Ahmad Tarhini, Yan Lin, Huang Lin, Zahra Rahman, Priyanka Vallabhaneni, Prateek Mendiratta, James F. Pingpank, Matthew P. Holtzman, Erik C. Yusko, Julie A. Rytlewski, Uma N. M. Rao, Robert L. Ferris, John M. Kirkwood
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Background Neoadjuvant immunotherapy utilizing novel combinations has the potential to transform the standard of care for locally/regionally advanced melanoma. We hypothesized that neoadjuvant ipilimumab in combination with high dose IFNα2b
Externí odkaz: https://doaj.org/article/e03efef202fb49679c2f6f0f0947635e
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3
Neoadjuvant ipilimumab (3 mg/kg or 10 mg/kg) and high dose IFN-α2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire
Autor: John M. Kirkwood, Yan Lin, Matthew P. Holtzman, Robert L. Ferris, James F. Pingpank, Prateek Mendiratta, Erik Yusko, Ahmad A. Tarhini, Zahra Rahman, Uma N. M. Rao, Priyanka Vallabhaneni, Huang Lin, Julie A. Rytlewski
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-10 (2018)
Journal for Immunotherapy of Cancer
Background Neoadjuvant immunotherapy utilizing novel combinations has the potential to transform the standard of care for locally/regionally advanced melanoma. We hypothesized that neoadjuvant ipilimumab in combination with high dose IFNα2b (HDI) is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f367068518c9ce09aa6e94cd69c329
http://link.springer.com/article/10.1186/s40425-018-0428-5
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4
A unique gene expression signature is significantly differentially expressed in tumor-positive or tumor-negative sentinel lymph nodes in patients with melanoma
Autor: Madeeha Ashraf, Uma N. M. Rao, William F. LaFramboise, Monica C. Panelli, Zahra Rahman, Hui-Min Lin, Cindy Sander, Priyanka Vallabhaneni, Theofanis Floros, John M. Kirkwood, Yan Lin, Ahmad A. Tarhini
Publikováno v: Melanoma research. 27(5)
The purpose of this study was to learn whether molecular characterization through gene expression profiling of node-positive and node-negative sentinel lymph nodes (SLNs) in patients with clinical stage I and II melanoma may improve the understanding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ceb21d459bb8a54f80e2cb0e510ff5
https://pubmed.ncbi.nlm.nih.gov/30371571
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5
Akademický článek
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6
Akademický článek
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7
Tumor associated PD-L1 expression pattern in microscopically tumor positive sentinel lymph nodes in patients with melanoma
Autor: Christopher R. Gibson, Rachel Dubner, Uma N. M. Rao, Zahra Rahman, Haris Zahoor, John M. Kirkwood, Ahmad A. Tarhini, Cindy Sander, Jennifer H. Yearley
Publikováno v: Journal of Translational Medicine
Background Characterization of PD-L1 expression within clinically/radiologically negative but microscopically tumor positive sentinel lymph nodes (SLN) is important to our understanding of the relevance of this immune checkpoint pathway for adjuvant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998eeb8cd2fed1c02d8403b303150247
http://europepmc.org/articles/PMC4589168
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8
Clonality of T-cell repertoire in the tumor microenvironment (TME) and peripheral blood of metastatic melanoma patients treated with CTLA4 blockade and interferon-α (IFN)
Autor: Priyanka Vallabhaneni, Ahmad A. Tarhini, Erik Yusko, Zahra Rahman, Sharon Benzeno, Aya Agha
Publikováno v: Journal of Clinical Oncology. 35:9-9
9 Background: Patients with metastatic melanoma were treated with tremelimumab and IFN in a previously reported study (Tarhini. J Clin Oncol. 2012). Clonality of T-cell repertoire was analyzed in terms of clinical response both in TME and in peripher
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0100881e4330c7296bb5be8a5f862a53
https://doi.org/10.1200/jco.2017.35.7_suppl.9
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10
Transcript profiling reveals mechanisms for lipid conservation during diapause in the mosquito, Aedes albopictus
Autor: Julie A. Reynolds, Zahra Rahman, Monica F. Poelchau, Peter Armbruster, David L. Denlinger
Publikováno v: Journal of insect physiology. 58(7)
The Asian tiger mosquito, Aedes albopictus, is a medically important invasive species whose geographic distribution has expanded dramatically during the past 20 years, and one of the key elements of its success is its capacity to survive long distanc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f401d0f5bbaf9c99523a3704edb61be4
https://pubmed.ncbi.nlm.nih.gov/22579567
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