Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zahra Mamdouh"'
Publikováno v:
The Journal of Experimental Medicine
Leukocyte migration across endothelial cell borders (paracellular) and through endothelial cells (transcellular) appear to be distinct processes. During paracellular migration, membrane from a parajunctional reticulum of interconnected vesicles, the
Publikováno v:
The Journal of Immunology. 182:5041-5051
PECAM-1/CD31 is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. A critical pool of PECAM-1 resides in the lateral border recycling compartment (LBRC). During TEM, membrane from the LBRC is redirected to sur
Publikováno v:
Nature Immunology. 5:393-400
Monocytes, like all leukocytes, undergo a series of sequential steps during extravasation from blood into tissues: tethering, rolling, adhesion and diapedesis. We have discovered an essential step, which we call locomotion, in which the monocyte move
Autor:
Nanda Beatini, Gregory A. Grabowski, Ira Tabas, Xavier Buton, Richik N. Ghosh, Frederick R. Maxfield, George Kuriakose, Hong Du, Zahra Mamdouh
Publikováno v:
Journal of Biological Chemistry. 274:32112-32121
A critical event in atherogenesis is the interaction of arterial wall macrophages with subendothelial lipoproteins. Although most studies have investigated this interaction by incubating cultured macrophages with monomeric lipoproteins dissolved in m
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1234:197-202
The effects of benzyl alcohol, a local anaesthetic commonly used for modification of membrane fluidity, on fluid phase endocytosis and on exocytosis have been investigated in MDCK cells. Fluid phase endocytosis in confluent cells monolayer grown on s
Publikováno v:
The Journal of Experimental Medicine
Diapedesis of leukocytes across endothelial cells is a crucial step in both the innate and adaptive immune responses. Surface molecules on leukocytes and endothelial cells critical for diapedesis have been identified, but the mechanisms underlying th
Publikováno v:
The FASEB Journal. 21
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1282(2):171-173
Temperature dependence of fluid-phase endocytosis was determined in two renal epithelial cell lines, MDCK cells and LLC-PK1 cells, using Lucifer Yellow or horseradish peroxidase as markers. For both cell lines, grown on solid support as a confluent m
Publikováno v:
Nature. 421(6924)
Leukocytes enter sites of inflammation by squeezing through the borders between endothelial cells that line postcapillary venules at that site. This rapid process, called transendothelial migration (TEM) or diapedesis, is completed within 90 s after
Publikováno v:
Nature immunology. 3(2)
CD99 is a heavily O-glycosylated 32-kD type I transmembrane protein that is expressed on most hematopoietic cells. We show here that CD99 is expressed on endothelial cells and is concentrated at the borders between confluent cells. We found that a mo