Výsledky vyhledávání - "Zahra Hossein-pour"

Non-specific peroxidase activity and catalase-inhibitory behavior of fibrillar aggregates after interaction with heme: relevance to the etiology of amyloid-related neurodegenerative disorders using the experimental-based evidences

Autor: Reza Khodarahmi, Sirous Ghobadi, Khirollah Yari, Kamran Mansouri, Zahra Hossein-pour, Seyyed Abolghasem Ghadami, Ali Mostafaie

Publikováno v: Journal of the Iranian Chemical Society. 9:939-950

The exact mechanism of cell death in neurodegenerative diseases remains obscure, but the aberrant assembly of proteins into fibrillar aggregates is accused to be the primary cause of pathogenesis. Furthermore, the structural determinants of protein f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4248e3d1bf9149173e4079f60c89653c
https://doi.org/10.1007/s13738-012-0111-6

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Synthesis and in vitro characterization of some benzothiazole- and benzofuranone-derivatives for quantification of fibrillar aggregates and inhibition of amyloid-mediated peroxidase activity

Autor: Hadi Adibi, Reza Khodarahmi, Sirous Ghobadi, Zahra Hossein-pour, Seyyed Abolghasem Ghadami

Publikováno v: Medicinal Chemistry Research. 22:115-126

Neurodegenerative diseases are characterized by amyloid deposition. Thioflavin T (ThT) is one of the molecules considered for detection of amyloid deposits; however, its lipophilicity is too low to cross the blood–brain barrier. Therefore, there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec6ecfd1a8935baa732359ce30c5b0aa
https://doi.org/10.1007/s00044-012-0012-3

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