Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zahra Haghighijoo"'
Autor:
Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohammad Hasan Jamei, Alireza Poustforoosh, Somayeh Nazari, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edraki
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triaz
Externí odkaz:
https://doaj.org/article/b3857a4241ff4145bf0fa7257831487f
Autor:
Timothy J. Baumgartner, Zahra Haghighijoo, Nana A. Goode, Nolan M. Dvorak, Parsa Arman, Fernanda Laezza
Publikováno v:
Life, Vol 13, Iss 8, p 1655 (2023)
Alzheimer’s disease (AD) is the most common cause of dementia and is classically characterized by two major histopathological abnormalities: extracellular plaques composed of amyloid beta (Aβ) and intracellular hyperphosphorylated tau. Due to the
Externí odkaz:
https://doaj.org/article/fef1634f70d849aa9cc6b82caaf5172e
Autor:
Zahra Haghighijoo, Zahra Rezaei, Mansooreh Jaberipoor, Samaneh Taheri, Meysam Jani, Soghra Khabnadideh
Publikováno v:
Research in Pharmaceutical Sciences, Vol 13, Iss 4, Pp 360-367 (2018)
Quinazoline is one of the most widespread scaffolds amongst natural and synthetic bioactive compounds. Recently the quinazoline derivatives and in particular the 4-anilinoquinazolines have attracted much attention for their anticancer properties due
Externí odkaz:
https://doaj.org/article/f573a2854673441597a04ed1ce00204f
Autor:
Mohammad Hasan Jamei, Mehdi khoshneviszadeh, Najmeh Edraki, Maryam Firoozi, Zahra Haghighijoo, Rmin Miri, Amirhossein sakhtaman
Publikováno v:
Trends in Pharmaceutical Sciences, Vol 2, Iss 4, Pp 253-258 (2016)
Apoptosis is critical for tissue homeostasis and for the physiological removal of abnormal cells. Bcl-2 family proteins are important regulators of apoptosis. It’s observed that antiapototic Bcl-2 family members are generally over expressed in many
Externí odkaz:
https://doaj.org/article/5accad3e19fb4ff5841ed9bca9da69f0
Publikováno v:
Trends in Pharmaceutical Sciences, Vol 1, Iss 3, Pp 173-178 (2015)
4-Anilinoquinazolines have been widely studied as anticancer agents. Despite the widespread utility of this class of compounds, the reported syntheses of 4-anilinoquinazolines require multistep and low-yielding pathways. A novel strategy to prepare 4
Externí odkaz:
https://doaj.org/article/2f9a7ec61f44497d9eeb6e6b170efdb2
Autor:
Aliasghar Jarrahpour, Zahra Jowkar, Zahra Haghighijoo, Roghayeh Heiran, Javad Ameri Rad, Véronique Sinou, Florent Rouvier, Christine Latour, Jean Michel Brunel, Namık Özdemir
Publikováno v:
Medicinal Chemistry Research
Medicinal Chemistry Research, Springer Verlag, 2022, 31 (6), pp.1026-1034. ⟨10.1007/s00044-022-02898-8⟩
Medicinal Chemistry Research, 2022, 31 (6), pp.1026-1034. ⟨10.1007/s00044-022-02898-8⟩
Medicinal Chemistry Research, Springer Verlag, 2022, 31 (6), pp.1026-1034. ⟨10.1007/s00044-022-02898-8⟩
Medicinal Chemistry Research, 2022, 31 (6), pp.1026-1034. ⟨10.1007/s00044-022-02898-8⟩
International audience; In our ongoing search for bioactive compounds, a class of novel spiro-β-lactam isatin hybrids has been synthesized through a [2 + 2] cycloaddition reaction from 1-allyl-3-(arylimino)indolin-2-one, ketenes and various aryloxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d00b5489b702855fa94302ad8a14c2
https://doi.org/10.1007/s00044-022-02898-8
https://doi.org/10.1007/s00044-022-02898-8
Autor:
Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohamad Hassan Jamei, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edraki
Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triazole moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::011f17a1e29ce7078f6026ad978b7188
https://doi.org/10.21203/rs.3.rs-1837075/v1
https://doi.org/10.21203/rs.3.rs-1837075/v1
Autor:
Najmeh Edraki, Malihe Hassanzadeh, Shabnam Mahernia, Zahra Haghighijoo, Aida Iraji, Mehdi Adib, Fariba Peytam, Mohammad Mahdavi, Massoud Amanlou
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:5803-5814
MiR-155 plays main roles in several physiological and pathological mechanisms, such as Down syndrome (DS), immunity and inflammation and potential anti-AD therapeutic target. The miR-155 is one of the overexpressed miRNAs in DS patients that contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967815e58bb2361098ed7b34d28a698e
https://doi.org/10.1080/07391102.2021.1873861
https://doi.org/10.1080/07391102.2021.1873861
Autor:
Shahriar Yari Boroujeni, Zahra Haghighijoo, Maryam Mohammadi‐Khanaposhtani, Ali Mosadeghkhah, Ali Moazzam, Ali Yavari, Manan Hajimahmoodi, Reyhaneh Sabourian, Samesadat Hosseini, Bagher Larijani, Halleh Hamedifar, Samira Ansari, Mohammad Mahdavi
Publikováno v:
Chemistry & Biodiversity. 19
A novel series of N-phenylacetamide-oxindole-thiosemicarbazide hybrids were synthesized and evaluated for their tyrosinase inhibitory activity. According to tyrosinase inhibition results, all the synthesized compounds showed high tyrosinase inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca341e76c0505244ab92074fe205ffba
https://doi.org/10.1002/cbdv.202100666
https://doi.org/10.1002/cbdv.202100666
Publikováno v:
European journal of medicinal chemistry. 227
Quinazolines are considered as a promising class of bioactive heterocyclic compounds with broad properties. Particularly, the quinazoline scaffold has an impressive role in the design and synthesis of new CNS-active drugs. The drug-like properties an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0433b3a1b0109dc019b0eac255d190ae
https://pubmed.ncbi.nlm.nih.gov/34742016
https://pubmed.ncbi.nlm.nih.gov/34742016