The Effect of 5-Aza-2'-Deoxycytidine in Combination to and in Comparison with Vorinostat on DNA Methyltransferases, Histone Deacetylase 1, Glutathione S-Transferase 1 and Suppressor of Cytokine Signaling 1 Genes Expression, Cell Growth Inhibition and Apoptotic Induction in Hepatocellular LCL-PI 11 Cell Line

Autor: Zahra Esmi, Fraidoon Kavoosi, Masumeh Sanaei

Publikováno v: International Journal of Hematology-Oncology and Stem Cell Research
International Journal of Hematology-Oncology and Stem Cell Research, Vol 14, Iss 1 (2020)

Background: Aberrant methylation and histone deacetylation of tumor suppressor genes (TSGs) are the most epigenetic alterations involving in tumorigenesis. Overexpression of DNA methyltransferases (DNMTs) and histone deacetylase 1 (HDAC1) have been r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea22f4e18dc70ec0b884452851212e3a
https://pubmed.ncbi.nlm.nih.gov/32337014