Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Zahra, Fagrouch"'
Autor:
Gerrit Koopman, Mario Amacker, Toon Stegmann, Ernst J. Verschoor, Babs E. Verstrepen, Farien Bhoelan, Denzel Bemelman, Kinga P. Böszörményi, Zahra Fagrouch, Gwendoline Kiemenyi-Kayere, Daniella Mortier, Dagmar E. Verel, Henk Niphuis, Roja Fidel Acar, Ivanela Kondova, Yolanda S. Kap, Willy M. J. M. Bogers, Petra Mooij, Sylvain Fleury
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Influenza virosomes serve as antigen delivery vehicles and pre-existing immunity toward influenza improves the immune responses toward antigens. Here, vaccine efficacy was evaluated in non-human primates with a COVID-19 virosome-based vaccin
Externí odkaz:
https://doaj.org/article/d338be50d6164ec6bb84aa6c67c59cee
Autor:
Petra Mooij, Daniella Mortier, Aafke Aartse, Alexandre B. Murad, Ricardo Correia, António Roldão, Paula M. Alves, Zahra Fagrouch, Dirk Eggink, Norbert Stockhofe, Othmar G. Engelhardt, Ernst J. Verschoor, Marit J. van Gils, Willy M. Bogers, Manuel J. T. Carrondo, Edmond J. Remarque, Gerrit Koopman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The first exposure to influenza is presumed to shape the B-cell antibody repertoire, leading to preferential enhancement of the initially formed responses during subsequent exposure to viral variants. Here, we investigated whether this principle rema
Externí odkaz:
https://doaj.org/article/fe0da1bcfd6c40f6beed32ab73a26fdd
Autor:
Paul J. Wichgers Schreur, Petra Mooij, Gerrit Koopman, Babs E. Verstrepen, Zahra Fagrouch, Daniella Mortier, Nikki van Driel, Jet Kant, Sandra van de Water, Willy M. Bogers, Carine Punt, Lucien van Keulen, Ernst J. Verschoor, Jeroen Kortekaas
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Rift Valley fever virus (RVFV) is an emerging mosquito-borne bunyavirus that is highly pathogenic to wild and domesticated ruminants, camelids, and humans. While animals are exclusively infected via mosquito bites, humans can also be infecte
Externí odkaz:
https://doaj.org/article/b3f01e713329487eb9a114f58d3b89f5
Autor:
Petra Mooij, Juan García-Arriaza, Patricia Pérez, Adrian Lázaro-Frías, Babs E. Verstrepen, Kinga P. Böszörményi, Daniella Mortier, Zahra Fagrouch, Gwendoline Kiemenyi-Kayere, Henk Niphuis, Roja Fidel Acar, Lisette Meijer, Marieke A. Stammes, Ivanela Kondova, Ernst J. Verschoor, Corine H. GeurtsvanKessel, Erwin de Bruin, Reina S. Sikkema, Joanna Luczkowiak, Rafael Delgado, Dolores Montenegro, Eugenia Puentes, Esteban Rodríguez, Willy M. J. M. Bogers, Gerrit Koopman, Mariano Esteban
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Novel safe, immunogenic, and effective vaccines are needed to control the COVID-19 pandemic, caused by SARS-CoV-2. Here, we describe the safety, robust immunogenicity, and potent efficacy elicited in rhesus macaques by a modified vaccinia virus Ankar
Externí odkaz:
https://doaj.org/article/1502963789df47ebbf7ca3cdec8cf7a0
Autor:
Olivia Goethals, Suzanne J. F. Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J. Verschoor, Babs E. Verstrepen, Zahra Fagrouch, J. Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K. McCracken, Gregory D. Gromowski, Wiriya Rutvisuttinunt, Richard G. Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier de Lamballerie, Laurent Chatel-Chaix, Gregg N. Milligan, David W. C. Beasley, Nigel Bourne, Alan D. T. Barrett, Arnaud Marchand, Tim H. M. Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf Bartenschlager, Willy M. Bogers, Johan Neyts, Marnix Van Loock
Publikováno v:
Nature. 615:678-686
Dengue is a major health threat and the number of symptomatic infections caused by the four dengue serotypes is estimated to be 96 million1 with annually around 10,000 deaths2. However, no antiviral drugs are available for the treatment or prophylaxi
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Studies on the function of PRDM9 in model systems and its evolution during vertebrate divergence shed light on the basic molecular mechanisms of hybrid sterility and its evolutionary consequences. However, information regarding PRDM9-homolog, PRDM7,
Externí odkaz:
https://doaj.org/article/1af46731446a40b4bd223071971e5ac7
Autor:
Annemiek Maaskant, Lisette Meijer, Zahra Fagrouch, Jaco Bakker, Leo van Geest, Dian G M Zijlmans, Babs E Verstrepen, Jan A M Langermans, Ernst J Verschoor, Marieke A Stammes
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0252941 (2021)
Medical imaging as method to assess the longitudinal process of a SARS-CoV-2 infection in non-human primates is commonly used in research settings. Bronchoalveolar lavage (BAL) is regularly used to determine the local virus production and immune effe
Externí odkaz:
https://doaj.org/article/b814de8b8b1f4754b53224eb3ef1a889
Autor:
William G, Branton, Jason P, Fernandes, Nazanin, Mohammadzadeh, Mathew A L, Doan, Jon D, Laman, Benjamin B, Gelman, Zahra, Fagrouch, Ivanela, Kondova, Petra, Mooij, Gerrit, Koopman, Christopher, Power
Publikováno v:
Brain, Behavior, and Immunity, 107, 110-123. ACADEMIC PRESS INC ELSEVIER SCIENCE
Background: Systemic inflammation accompanies HIV-1 infection, resulting in microbial translocation from different tissues. We investigated interactions between lentivirus infections, neuroinflammation and microbial molecule presence in the brain. Me
Autor:
Andrew D. White, Laura Sibley, Jennie Gullick, Charlotte Sarfas, Simon Clark, Zahra Fagrouch, Ernst Verschoor, Francisco J. Salguero, Mike Dennis, Sally Sharpe
Publikováno v:
Vaccines, Vol 9, Iss 9, p 945 (2021)
This pilot study aimed to determine the utility of a cynomolgus macaque model of coinfection with simian immunodeficiency virus (SIV) for the assessment of vaccines designed to prevent reactivation of TB. Following infection caused by aerosol exposur
Externí odkaz:
https://doaj.org/article/d0557a849ef64b86ad3da5d12754f14b
Autor:
Philippe V Afonso, Zahra Fagrouch, Martin Deijs, Henk Niphuis, Willy Bogers, Antoine Gessain, Lia van der Hoek, Ernst J Verschoor
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007521 (2019)
BackgroundPrimate T-lymphotropic viruses type 1 (PTLV-1) are complex retroviruses infecting both human (HTLV-1) and simian (STLV-1) hosts. They share common epidemiological, clinical and molecular features. In addition to the canonical gag, pol, env
Externí odkaz:
https://doaj.org/article/7a34e08c887b45efb9ffbe122ad6301d