Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zaher Raslan"'
Autor:
Jawad S. Khalil, Robert Law, Zaher Raslan, Lih T. Cheah, Matthew S. Hindle, Ahmed A. Aburima, Mark T. Kearney, Khalid M. Naseem
Publikováno v:
Cells, Vol 13, Iss 13, p 1104 (2024)
Platelet activation is critical for haemostasis, but if unregulated can lead to pathological thrombosis. Endogenous platelet inhibitory mechanisms are mediated by prostacyclin (PGI2)-stimulated cAMP signalling, which is regulated by phosphodiesterase
Externí odkaz:
https://doaj.org/article/5fd59ece11a54f34802ee4458193261a
Autor:
Martin Berger, Katie Wraith, Casey Woodward, Ahmed Aburima, Zaher Raslan, Matthew S. Hindle, Julia Moellmann, Maria Febbraio, Khalid M. Naseem
Publikováno v:
Platelets, Vol 30, Iss 4, Pp 467-472 (2019)
Oxidized low-density lipoprotein (oxLDL) and associated oxidized phosphocholine-headgroup phospholipids (oxPCs) activate blood platelets through ligation of the scavenger receptor CD36. Previously, we found that oxLDL stimulated phosphorylation of ph
Externí odkaz:
https://doaj.org/article/9f0e35edf90e43f69af128f4ee3f3a2c
Autor:
Martin Berger, Zaher Raslan, Ahmed Aburima, Simbarashe Magwenzi, Katie S. Wraith, Benjamin E.J. Spurgeon, Matthew S. Hindle, Robert Law, Maria Febbraio, Khalid M. Naseem
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Prostacyclin (PGI2) controls platelet activation and thrombosis through a cyclic adenosine monophosphate (cAMP) signaling cascade. However, in patients with cardiovascular diseases this protective mechanism fails for reasons that are unclear. Using b
Externí odkaz:
https://doaj.org/article/0727a8ad821745a597e71829c681e558
Autor:
Christopher W. Smith, Zaher Raslan, Lola Parfitt, Abdullah O. Khan, Pushpa Patel, Yotis A. Senis, Alexandra Mazharian
Publikováno v:
Blood Advances, Vol 2, Iss 16, Pp 2072-2078 (2018)
Externí odkaz:
https://doaj.org/article/ad2fad50bf3c4daea89e7b5a33100cd8
Autor:
Nadira Yuldasheva, Victoria Ridger, Adomas Baranauskas, Simon D. Connell, Majid Ali, Richard M Cubbon, Stephen R. Baker, Ramzi A. Ajjan, Zaher Raslan, Helen Philippou, Cédric Duval, Helen R. McPherson, Khalid M. Naseem, Marc A. Bailey, Tímea Feller, Lih T. Cheah, Robert A. S. Ariëns
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Pulmonary embolism and stroke are thromboembolic diseases affecting >1 million people annually worldwide. Thromboembolism involves clot fragments affecting vital downstream organs such as the lung or brain. The mechanisms underpinning th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f3d938469db476b95359a06559028f
http://europepmc.org/articles/PMC8271579
http://europepmc.org/articles/PMC8271579
Autor:
Katie S. Wraith, Matthew S. Hindle, Benjamin E. J. Spurgeon, Martin Berger, Maria Febbraio, Robert Law, Ahmed Aburima, Zaher Raslan, Khalid M. Naseem, Simbarashe Magwenzi
Publikováno v:
Haematologica
Prostacyclin (PGI2) controls platelet activation and thrombosis through a cyclic adenosine monophosphate (cAMP) signalling cascade. However, in patients with cardiovascular diseases this protective mechanism fails for reasons that are unclear. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30713bd7e5a09f27ac796354c6afe41
https://doi.org/10.3324/haematol.2018.213348
https://doi.org/10.3324/haematol.2018.213348
Autor:
Katie S. Wraith, Ahmed Aburima, Zaher Raslan, Matthew S. Hindle, Casey Woodward, Julia Moellmann, Khalid M. Naseem, Martin Berger, Maria Febbraio
Publikováno v:
Platelets
Oxidized low-density lipoprotein (oxLDL) and associated oxidized phosphocholine-headgroup phospholipids (oxPCs) activate blood platelets through ligation of the scavenger receptor CD36. Previously, we found that oxLDL stimulated phosphorylation of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9679fd8d27937fca61bb1aa419a863c5
http://europepmc.org/articles/PMC6457275
http://europepmc.org/articles/PMC6457275
Autor:
Linde Meyaard, Marie Lordkipanidzé, Zaher Raslan, Alexandra Mazharian, Pushpa Patel, Steven G. Thomas, Danai Bem, Steve P. Watson, Christopher W Smith, Yotis A. Senis, Maxwell Byrne
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37:823-835
Objective— Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is a collagen receptor that belongs to the inhibitory immunoreceptor tyrosine-based inhibition motif–containing receptor family. It is an inhibitor of signaling via the immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1062b02bf294e84220539a22ff4ca256
https://doi.org/10.1161/atvbaha.117.309253
https://doi.org/10.1161/atvbaha.117.309253
Autor:
Zaher Raslan, Pushpa Patel, Alexandra Mazharian, Lola Parfitt, Christopher W Smith, Yotis A. Senis, Abdullah O. Khan
Key Points Platelet activation in vitro results in a more rapid and greater upregulation of TLT-1 surface expression compared with P-selectin. TLT-1 is more rapidly translocated to the surface of activated platelets than P-selectin during thrombus fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a82fcbad12878c60896da779ffecce
https://europepmc.org/articles/PMC6113608/
https://europepmc.org/articles/PMC6113608/
Autor:
R Law, J Rossington, Maria Febbraio, C. Woodwaard, Zaher Raslan, Matthew S. Hindle, Martin Berger, Benjamin E. J. Spurgeon, K. Wraith, A. Aburima, K M Naseem, S Magwenzi, Nikolaus Marx
Publikováno v:
European Heart Journal. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e595aef3f6afe73ed9ff69cc02caf89f
https://doi.org/10.1093/eurheartj/ehy566.5060
https://doi.org/10.1093/eurheartj/ehy566.5060