Effects of RBT-1 on preconditioning response biomarkers in patients undergoing coronary artery bypass graft or heart valve surgery: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial.

Autor: Lamy A; Department of Perioperative Medicine and Surgery, Population Health Research Institute, Hamilton, Ontario, Canada., Chertow GM; Departments of Medicine and Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA., Jessen M; Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA., Collar A; Department of Thoracic Surgery and Vascular Surgery, MyMichigan Health, Midland, MI, USA., Brown CD; Department of Cardiac Surgery, New Brunswick Heart Centre, Saint John, New Brunswick, Canada., Mack CA; Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA., Marzouk M; Department of Cardiac Surgery, Québec Heart and Lung Institute, Québec, Québec, Canada., Scavo V; Department of Cardiovascular and Thoracic Surgery, Lutheran Medical Group, Fort Wayne, Indiana, USA., Washburn TB; Department of Cardiothoracic Surgery, Huntsville Hospital Heart Center, Huntsville, AL, USA., Savage D; Department of Cardiothoracic Surgery, Indiana University Health, Bloomington, IN, USA., Smith J; Department of Surgery (School of Clinical Sciences at Monash Health), Monash University and Department of Cardiothoracic Surgery, Monash Health, Melbourne, Victoria, Australia., Bennetts J; Department of Cardiothoracic Surgery, Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, Australia.; Department of Surgery, College of Medicine and Public Health, Flinders University, Adelaide, Australia., Assi R; Department of Cardiac Surgery, Yale University School of Medicine, New Haven, CT, USA., Shults C; Department of Cardiac Surgery, MedStar Heart and Vascular Institute, Washington, DC, USA., Arghami A; Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA., Butler J; Department of Medicine, University of Mississippi, Jackson, MS, USA.; Baylor Scott and White Research Institute, Dallas, TX, USA., Devereaux PJ; Department of Perioperative Medicine and Surgery, Population Health Research Institute, Hamilton, Ontario, Canada., Zager R; Department of Drug Development & Medical Affairs, Renibus Therapeutics Inc, Southlake, TX, USA., Wang C; Pharma Data Associates LLC, Piscataway, NJ, USA., Snapinn S; Seattle-Quilcene Biostatistics LLC, Seattle, WA, USA., Browne A; Department of Perioperative Medicine and Surgery, Population Health Research Institute, Hamilton, Ontario, Canada., Rodriguez J; Department of Drug Development & Medical Affairs, Renibus Therapeutics Inc, Southlake, TX, USA., Ruiz S; Department of Drug Development & Medical Affairs, Renibus Therapeutics Inc, Southlake, TX, USA., Singh B; Department of Drug Development & Medical Affairs, Renibus Therapeutics Inc, Southlake, TX, USA.

Publikováno v: EClinicalMedicine [EClinicalMedicine] 2024 Jan 08; Vol. 68, pp. 102364. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2024).

Phospholipase A 2 Activity Can Protect Renal Tubules from Oxygen Deprivation Injury

Autor: Zager, R. A., Schimpf, B. A., Gmur, D. J., Burke, T. J.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1993 Sep 01. 90(17), 8297-8301.

Externí odkaz: https://www.jstor.org/stable/2363013

Oxidant‐ induced preconditioning: A pharmacologic approach for triggering renal 'self defense'.

Publikováno v: Physiological Reports. Oct2022, Vol. 10 Issue 20, p1-15. 15p.

The definition of acute kidney injury - Authors' reply.

Autor: Barasch J; Department of Medicine, Columbia University, New York, NY 10032, USA. Electronic address: jmb4@columbia.edu., Zager R; Fred Hutchinson Cancer Center, University of Washington, Washington, DC, USA., Bonventre JV; Fred Hutchinson Cancer Center, University of Washington, Washington, DC, USA.

Publikováno v: Lancet (London, England) [Lancet] 2018 Jan 20; Vol. 391 (10117), pp. 203-204.

Ischemic proximal tubular injury primes mice to endotoxin-induced TNF-α generation and systemic release.

Autor: Zager, R. A., Johnson, Ali C. M., Hanson, Sherry Y., Lund, Steve

Publikováno v: American Journal of Physiology: Renal Physiology; Aug2005, Vol. 289, pF289-F297, 9p, 6 Diagrams