Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Zafiroula Georgoussi"'
Autor:
Christos Karoussiotis, Aggeliki Sotiriou, Alexia Polissidis, Alexandra Symeonof, Danae Papavranoussi-Daponte, Vassiliki Nikoletopoulou, Zafiroula Georgoussi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Recent evidence has shown that G protein-coupled receptors (GPCRs) are direct sensors of the autophagic machinery and opioid receptors regulate neuronal plasticity and neurotransmission with an as yet unclarified mechanism. Using in vitro and in vivo
Externí odkaz:
https://doaj.org/article/b851696575124806880da1cfeb859931
Autor:
Lorella Pasquinucci, Carmela Parenti, Zafiroula Georgoussi, Lorena Reina, Emilia Tomarchio, Rita Turnaturi
Publikováno v:
Molecules, Vol 26, Iss 14, p 4168 (2021)
Although persistent pain is estimated to affect about 20% of the adult population, current treatments have poor results. Polypharmacology, which is the administration of more than one drug targeting on two or more different sites of action, represent
Externí odkaz:
https://doaj.org/article/a351c3754d5d4c5dbf87fc1611684c66
Autor:
Christos Karoussiotis, Aggeliki Sotiriou, Alexia Polissidis, Alexandra Symeonof, Danai Papavranoussi-Daponte, Vassiliki Nikoletopoulou, Zafiroula Georgoussi
Recent evidence has shown that G protein-coupled receptors (GPCRs) are direct sensors of the autophagic machinery and οpioid receptors regulate neuronal plasticity and neurotransmission with an as yet unclarified mechanism. Using in vitro and in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::552fec271e29c9534be4bac1f275732c
https://doi.org/10.22541/au.166127098.82640451/v1
https://doi.org/10.22541/au.166127098.82640451/v1
Autor:
Kostas Iatrou, Georgia Kythreoti, Trias Thireou, Christos Karoussiotis, Zafiroula Georgoussi, Spyros E. Zographos, Panagiota Liggri, Antonios Michaelakis, Stefan Schulz
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa6a5938e7b9a56b8cf73a747712991b
https://doi.org/10.1096/fasebj.2022.36.s1.r4433
https://doi.org/10.1096/fasebj.2022.36.s1.r4433
Autor:
Zafiroula Georgoussi, Christos Karoussiotis, Aggeliki Sotiriou, Alexia V. Polissidis, Danae Papavranoussi‐Daponte, Alexandra Symeonof, Vassiliki Nikoletopoulou
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca655f2c1c86eacc1062f8ff6b4e27ad
https://doi.org/10.1096/fasebj.2022.36.s1.r2502
https://doi.org/10.1096/fasebj.2022.36.s1.r2502
Autor:
Rita Turnaturi, Carmela Parenti, Orazio Prezzavento, Agostino Marrazzo, Paschalina Pallaki, Zafiroula Georgoussi, Emanuele Amata, Lorella Pasquinucci
Publikováno v:
Molecules, Vol 23, Iss 3, p 677 (2018)
The opioid pharmacological profile of cis-(−)-N-normetazocine derivatives is deeply affected by the nature of their N-substituents. Here, our efforts were focused on the synthesis and pharmacological evaluation of novel derivatives of the lead LP1,
Externí odkaz:
https://doaj.org/article/534692b1e0004998bda30f1bf543247b
Autor:
Zafiroula Georgoussi, Alexandra Symeonof, Maria Marti-Solano, Tomasz Maciej Stepniewski, Christos Karoussiotis, Jana Selent
Publikováno v:
The FEBS Journal. 287:736-748
The δ-opioid receptor (δ-OR) couples to Gi/Go proteins to modulate a variety of responses in the nervous system. Τhe regulator of G protein signalling 4 (RGS4) was previously shown to directly interact within the C-terminal region of δ-OR using i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dde1ab1218f2f6cb8962fe185d654b0
https://doi.org/10.1111/febs.15033
https://doi.org/10.1111/febs.15033
Autor:
Panagiota Tsitoura, Evi Andronopoulou, Daniela Tsikou, Adamantia Agalou, Maria P Papakonstantinou, Georgia A Kotzia, Vassiliki Labropoulou, Luc Swevers, Zafiroula Georgoussi, Kostas Iatrou
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15428 (2010)
A lepidopteran insect cell-based expression system has been employed to express three Anopheles gambiae odorant receptors (ORs), OR1 and OR2, which respond to components of human sweat, and OR7, the ortholog of Drosophila's OR83b, the heteromerizatio
Externí odkaz:
https://doaj.org/article/55590cc00ea04c5c8b8a61ed4b0404c4
Autor:
Lorella Pasquinucci, Orazio Prezzavento, Giuseppina Cantarella, Giuseppina Aricò, Emanuela Arena, Rita Turnaturi, Zafiroula Georgoussi, Carmela Parenti, Rosalba Parenti
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:4745-4752
Pain relief achieved by co-administration of drugs acting at different targets is more effective than that obtained with conventional MOR selective agonists usually associated to relevant side effects. It has been demonstrated that simultaneously tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db9f3f84388eb99af019edd0197a980
https://doi.org/10.1016/j.bmc.2017.07.021
https://doi.org/10.1016/j.bmc.2017.07.021
Autor:
Lorella, Pasquinucci, Carmela, Parenti, M Carmen, Ruiz-Cantero, Zafiroula, Georgoussi, Paschalina, Pallaki, Enrique J, Cobos, Emanuele, Amata, Agostino, Marrazzo, Orazio, Prezzavento, Emanuela, Arena, Maria, Dichiara, Loredana, Salerno, Rita, Turnaturi
Publikováno v:
ACS Med Chem Lett
[Image: see text] Modifications at the basic nitrogen of the benzomorphan scaffold allowed the development of compounds able to segregate physiological responses downstream of the receptor signaling, opening new possibilities in opioid drug developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fa48c277ce2dca4ce13a441ead03c41
https://pubmed.ncbi.nlm.nih.gov/32435370
https://pubmed.ncbi.nlm.nih.gov/32435370