Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Zafar K Khan"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 3 (2014)
Dextran, the α-1,6-linked glucose polymer widely used in biology and medicine, promises new applications. Linear dextran applied as a blood plasma substitute demonstrates a high rate of biocompatibility. Dextran is present in foods, drugs, and vacci
Externí odkaz:
https://doaj.org/article/baa7946e50c34ff487161917696423af
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34490 (2012)
RNA interference (RNAi) is a natural cellular mechanism to silence gene expression and is predominantly mediated by microRNAs (miRNAs) that target messenger RNA. Viruses can manipulate the cellular processes necessary for their replication by targeti
Externí odkaz:
https://doaj.org/article/05fee2ef32a4466cb51ccb2c50fbbb30
Autor:
Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain
Publikováno v:
Haematologica, Vol 107, Iss 12 (2022)
Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1). Patients suffering from ATLL present a poor prognosis and have a dearth of treatment options. In
Externí odkaz:
https://doaj.org/article/a0e484c8851347b0903ce1d12f0f35ba
Autor:
Dominic Sales, Edward Lin, Victoria Stoffel, Shallyn Dickson, Zafar K. Khan, Joris Beld, Pooja Jain
Publikováno v:
NeuroImmune Pharmacology and Therapeutics.
Objectives HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory autoimmune disease characterized by high levels of infected immortalized T cells in circulation, which makes it difficult for antiretroviral (ART) d
Autor:
Benjamin Rahmani, Edward Lin, Pooja Jain, Neha Puttagunta, Julie Joseph, Yonesha Cole, Zafar K. Khan
Publikováno v:
J Neuroimmune Pharmacol
Immune checkpoints (ICPs) are major co-signaling pathways that trigger effector functions in immune cells, with isoforms that are either membrane bound, engaging in direct cell to cell activation locally, or soluble, acting at distant sites by circul
Autor:
Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain
Publikováno v:
Haematologica. 107(12)
Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1). Patients suffering from ATLL present a poor prognosis and have a dearth of treatment options. In
Autor:
B. Hilda Ye, Catherine DeMarino, Julie Joseph, Dominc Sales, Murali Janakiram, Isabelle Lemasson, Sydney Wilson, Pooja Jain, Zafar K. Khan, Edward W. Harhaj, Amanda W. Rushing, Fatah Kashanchi, Vanessa Teixeira, Rashida Ginwala, Kiran Madugula
Background. HTLV-1 is a complex human retrovirus and an etiologic agent causing a malignant and intractable T-cell neoplasia termed Adult T-cell leukemia and lymphoma (ATLL). Patients suffering from ATLL present with poor prognoses and a dearth of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb38d27d38b446c297f5625cf6577fb
https://doi.org/10.21203/rs.3.rs-362537/v1
https://doi.org/10.21203/rs.3.rs-362537/v1
Autor:
Kiran Madugula, Dip Patel, Edward W. Harhaj, Pooja Jain, Ria Mulherkar, DeGaulle I. Chigbu, Zafar K. Khan
Publikováno v:
Oncotarget
Myocyte enhancer factor (MEF)-2 plays a critical role in proliferation, differentiation, and development of various cell types in a tissue specific manner. Four isoforms of MEF-2 (A-D) differentially participate in controlling the cell fate during th
Autor:
Zafar K. Khan, Mariana Bernui, Frank Bearoff, Patrick Moore, Raina Bhavsar, Mitzi Nagarkatti, Rashida Ginwala, Narendra P. Singh, Pooja Jain
Publikováno v:
J Neuroimmune Pharmacol
Neuroinflammation leads to tissue injury causing many of the clinical symptoms of Multiple Sclerosis, an autoimmune disorder of the central nervous system (CNS). While T cells, specifically Th1 and Th17 cells, are the ultimate effectors of this disea
Rapidly growing technologies in genomic knowledgebase have tremendously fastened the process of transgenesis. The clustered regularly interspaced short palindromic repeat system eases the positional integration of the gene of interest in animal model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::865521520f79120af4cf6cb4e8cef0b0
https://doi.org/10.1016/b978-0-12-811710-1.00021-5
https://doi.org/10.1016/b978-0-12-811710-1.00021-5