Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Zafar K Khan"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 3 (2014)
Dextran, the α-1,6-linked glucose polymer widely used in biology and medicine, promises new applications. Linear dextran applied as a blood plasma substitute demonstrates a high rate of biocompatibility. Dextran is present in foods, drugs, and vacci
Externí odkaz:
https://doaj.org/article/baa7946e50c34ff487161917696423af
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34490 (2012)
RNA interference (RNAi) is a natural cellular mechanism to silence gene expression and is predominantly mediated by microRNAs (miRNAs) that target messenger RNA. Viruses can manipulate the cellular processes necessary for their replication by targeti
Externí odkaz:
https://doaj.org/article/05fee2ef32a4466cb51ccb2c50fbbb30
Autor:
Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain
Publikováno v:
Haematologica, Vol 107, Iss 12 (2022)
Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1). Patients suffering from ATLL present a poor prognosis and have a dearth of treatment options. In
Externí odkaz:
https://doaj.org/article/a0e484c8851347b0903ce1d12f0f35ba
Autor:
Dominic Sales, Edward Lin, Victoria Stoffel, Shallyn Dickson, Zafar K. Khan, Joris Beld, Pooja Jain
Publikováno v:
NeuroImmune Pharmacology and Therapeutics.
Objectives HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory autoimmune disease characterized by high levels of infected immortalized T cells in circulation, which makes it difficult for antiretroviral (ART) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea972a0bf63c0ae512f239c649da4139
https://doi.org/10.1515/nipt-2022-0017
https://doi.org/10.1515/nipt-2022-0017
Autor:
Benjamin Rahmani, Edward Lin, Pooja Jain, Neha Puttagunta, Julie Joseph, Yonesha Cole, Zafar K. Khan
Publikováno v:
J Neuroimmune Pharmacol
Immune checkpoints (ICPs) are major co-signaling pathways that trigger effector functions in immune cells, with isoforms that are either membrane bound, engaging in direct cell to cell activation locally, or soluble, acting at distant sites by circul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f244c9acf3d7bdfdae024c429a4f45eb
https://doi.org/10.1007/s11481-021-10018-3
https://doi.org/10.1007/s11481-021-10018-3
Publikováno v:
Antioxidants, Vol 8, Iss 2, p 35 (2019)
Inflammation has been reported to be intimately linked to the development or worsening of several non-infectious diseases. A number of chronic conditions such as cancer, diabetes, cardiovascular disorders, autoimmune diseases, and neurodegenerative d
Externí odkaz:
https://doaj.org/article/84731c236a4546038252529627518026
Autor:
Kiran Madugula, Dip Patel, Edward W. Harhaj, Pooja Jain, Ria Mulherkar, DeGaulle I. Chigbu, Zafar K. Khan
Publikováno v:
Oncotarget
Myocyte enhancer factor (MEF)-2 plays a critical role in proliferation, differentiation, and development of various cell types in a tissue specific manner. Four isoforms of MEF-2 (A-D) differentially participate in controlling the cell fate during th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d671823a5efd37b91019833ee6cdc4
http://europepmc.org/articles/PMC6505634
http://europepmc.org/articles/PMC6505634
Autor:
Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain
Publikováno v:
Haematologica. 107(12)
Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1). Patients suffering from ATLL present a poor prognosis and have a dearth of treatment options. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295a832c80345c7bd672831ecaf205a3
https://pubmed.ncbi.nlm.nih.gov/35615924
https://pubmed.ncbi.nlm.nih.gov/35615924
Autor:
B. Hilda Ye, Catherine DeMarino, Julie Joseph, Dominc Sales, Murali Janakiram, Isabelle Lemasson, Sydney Wilson, Pooja Jain, Zafar K. Khan, Edward W. Harhaj, Amanda W. Rushing, Fatah Kashanchi, Vanessa Teixeira, Rashida Ginwala, Kiran Madugula
Background. HTLV-1 is a complex human retrovirus and an etiologic agent causing a malignant and intractable T-cell neoplasia termed Adult T-cell leukemia and lymphoma (ATLL). Patients suffering from ATLL present with poor prognoses and a dearth of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb38d27d38b446c297f5625cf6577fb
https://doi.org/10.21203/rs.3.rs-362537/v1
https://doi.org/10.21203/rs.3.rs-362537/v1
Autor:
Zafar K. Khan, Mariana Bernui, Frank Bearoff, Patrick Moore, Raina Bhavsar, Mitzi Nagarkatti, Rashida Ginwala, Narendra P. Singh, Pooja Jain
Publikováno v:
J Neuroimmune Pharmacol
Neuroinflammation leads to tissue injury causing many of the clinical symptoms of Multiple Sclerosis, an autoimmune disorder of the central nervous system (CNS). While T cells, specifically Th1 and Th17 cells, are the ultimate effectors of this disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37756272b3ed96237a7fb126d1c25d0
https://pubmed.ncbi.nlm.nih.gov/32607691
https://pubmed.ncbi.nlm.nih.gov/32607691