Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Zacopride"'
Akademický článek
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Autor:
Qing-Hua Liu, Xi Qiao, Li-Jun Zhang, Jin Wang, Li Zhang, Xu-Wen Zhai, Xiao-Ze Ren, Yu Li, Xiao-Na Cao, Qi-Long Feng, Ji-Min Cao, Bo-Wei Wu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Intracellular Ca2+ overload, prolongation of the action potential duration (APD), and downregulation of inward rectifier potassium (IK1) channel are hallmarks of electrical remodeling in cardiac hypertrophy and heart failure (HF). We hypothesized tha
Externí odkaz:
https://doaj.org/article/dcfb8b8d09654bc3b170c140e314b83d
Autor:
Qing-Hua Liu, Qi-Long Feng, Junhu Li, Jimin Cao, Baozhong Zhu, Yuan-Yuan Lin, Bo-Wei Wu, Xuewen Li, Yanlin Guo, Bingmei Chang, Xiaojie Bai
Publikováno v:
Current Pharmaceutical Design. 26:5746-5754
Background: Zacopride, a potent antagonist of 5-HT3 receptors and an agonist of 5-HT4 receptors, is a gastrointestinal prokinetic agent. In a previous study, we discovered that zacopride selectively stimulated the inward rectifier potassium current (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0921bfa43fb5d5798a885825a4713465
https://doi.org/10.2174/1381612826666200701135508
https://doi.org/10.2174/1381612826666200701135508
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Yu Li, Qing-Hua Liu, Jimin Cao, Li Zhang, Xiao-Ze Ren, Jin Wang, Qi-Long Feng, Bo-Wei Wu, Xu-Wen Zhai, Li-Jun Zhang, Xi Qiao, Xiao-Na Cao
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Intracellular Ca2+ overload, prolongation of the action potential duration (APD), and downregulation of inward rectifier potassium (IK1) channel are hallmarks of electrical remodeling in cardiac hypertrophy and heart failure (HF). We hypothesized tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cb80754a35e514ee065c79187933c4
https://doi.org/10.3389/fphar.2019.00929
https://doi.org/10.3389/fphar.2019.00929
Autor:
Suliana Mesquita Paula, Carlos Alberto Oliveira-Silva, Mônica de Oliveira Belém, Daniel Maia Nogueira de Oliveira, Emanuella Feitosa de Carvalho, Kalinne Kelly Lima Gadelha, Pedro Jorge Caldas Magalhães, Armênio Aguiar dos Santos, Karine Lima-Silva, Camila Gadelha Pinheiro, Ana Karolina Martins Cavalcante
Publikováno v:
European Journal of Pharmacology. 908:174339
This study tested the effects of β-methylphenylethylamine (β-MPEA) and octopamine on contractile parameters of the gastrointestinal tract in rats. We hypothesized that some of their effects result from interactions with trace amine (TA)-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d9ac954773b1a87c1cbfacfa1d4f14
https://doi.org/10.1016/j.ejphar.2021.174339
https://doi.org/10.1016/j.ejphar.2021.174339
Autor:
Emre Bektik, Valeriy Timofeyev, Isabelle Deschenes, Adrienne T. Dennis, Ji-Dong Fu, Yu Sun, Ronald A. Li, Xiaoping Wan, Kenneth R. Laurita
Publikováno v:
Stem Cell Reviews and Reports. 13:631-643
The inward rectifier potassium current (IK1) is generally thought to suppress cardiac automaticity by hyperpolarizing membrane potential (MP). We recently observed that IK1 could promote the spontaneously-firing automaticity induced by upregulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cf812fd74c499ab582f8c2ef761023c
https://doi.org/10.1007/s12015-017-9745-1
https://doi.org/10.1007/s12015-017-9745-1
Autor:
Qing-Hua, Liu, Xi, Qiao, Li-Jun, Zhang, Jin, Wang, Li, Zhang, Xu-Wen, Zhai, Xiao-Ze, Ren, Yu, Li, Xiao-Na, Cao, Qi-Long, Feng, Ji-Min, Cao, Bo-Wei, Wu
Publikováno v:
Frontiers in Pharmacology
Intracellular Ca2+ overload, prolongation of the action potential duration (APD), and downregulation of inward rectifier potassium (IK1) channel are hallmarks of electrical remodeling in cardiac hypertrophy and heart failure (HF). We hypothesized tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba33f120004896fc70aaae8f709d3702
https://pubmed.ncbi.nlm.nih.gov/31507422
https://pubmed.ncbi.nlm.nih.gov/31507422
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Li-Jun Zhang, Li Zhang, Qing-Hua Liu, Qi-Long Feng, Bo-Wei Wu, Dong-Ming Wang, Xu-Wen Zhai, Jimin Cao, Xi Qiao
Publikováno v:
Life Sciences. 239:117075
Aims Arrhythmogenesis of chronic myocardial infarction (MI) is associated with the prolongation of action potential, reduction of inward rectifier potassium (IK1, Kir) channels and hyper-activity of Calcium/calmodulin-dependent kinase II (CaMKII) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27016fe2a39763dcf837d54cec05ca2
https://doi.org/10.1016/j.lfs.2019.117075
https://doi.org/10.1016/j.lfs.2019.117075