Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zack Zurawski"'
Autor:
Ryan P. Ceddia, Zack Zurawski, Analisa Thompson Gray, Feyisayo Adegboye, Ainsley McDonald-Boyer, Fubiao Shi, Dianxin Liu, Jose Maldonado, Jiesi Feng, Yulong Li, Simon Alford, Julio E. Ayala, Owen P. McGuinness, Sheila Collins, Heidi E. Hamm
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Negative regulation of exocytosis from secretory cells is accomplished through inhibitory signals from Gi/o GPCRs by Gβγ subunit inhibition of 2 mechanisms: decreased calcium entry and direct interaction of Gβγ with soluble N-ethylmaleimide–sen
Externí odkaz:
https://doaj.org/article/a5ee21a0d0b84d4e9b842e9bacb8ba19
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The nucleus accumbens (NAc) guides reward-related motivated behavior implicated in pathological behavioral states, including addiction and depression. These behaviors depend on the precise neuromodulatory actions of Gi/o-coupled G-protein-coupled rec
Externí odkaz:
https://doaj.org/article/e89aa25bf4924d6aaa513aa36223badc
Autor:
Emily Church, Edaeni Hamid, Zack Zurawski, Mariana Potcoava, Eden Flores-Barrera, Adriana Caballero, Kuei Y. Tseng, Simon Alford
Publikováno v:
J Neurosci
In presynaptic terminals, membrane-delimited Gi/o-mediated presynaptic inhibition is ubiquitous and acts via Gβγ to inhibit Ca2+entry, or directly at SNARE complexes to inhibit Ca2+-dependent synaptotagmin-SNARE complex interactions. At CA1-subicul
While the ability of G protein βγ subunits (Gβγ) to bind to and functionally inhibit the neuronal SNARE proteins Stx1A, SNAP25, and synaptobrevin in the presence of the calcium sensor synaptotagmin I is well documented, these three SNARE proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9690f0f44ec6eb354b3aeea89b0054ec
https://doi.org/10.1101/2022.05.30.494040
https://doi.org/10.1101/2022.05.30.494040
Publikováno v:
Cell reports
SUMMARY Inhibition of neurotransmitter release by neurotransmitter substances constitutes a fundamental means of neuromodulation. In contrast to well-delineated mechanisms that underlie inhibition of evoked release via suppression of voltage-gated Ca
Autor:
Heidi E. Hamm, Anna Eitel, Zack Zurawski, Benjamin K. Mueller, Ali Kaya, Jens Meiler, Yun Yim
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Neuroreport
Three SNARE proteins, SNAP-25, syntaxin 1A, and VAMP2 or synaptobrevin 2, constitute the minimal functional machinery needed for the regulated secretion of neurotransmitters. Dynamic changes in the regulated release of neurotransmitters are associate
Publikováno v:
Pharmacology & Therapeutics. 192:124-140
Modulation of neurotransmitter exocytosis by activated G(i/o) coupled G-protein coupled receptors (GPCRs) is a universal regulatory mechanism used both to avoid overstimulation and to influence circuitry. One of the known modulation mechanisms is the
Autor:
Emily Church, Edaeni Hamid, Zack Zurawski, Mariana Potcoava, Eden Flores-Barrera, Adriana Caballero, Kuei Y. Tseng, Simon Alford
In presynaptic terminals, membrane-delimited Gi/o-mediated presynaptic inhibition is ubiquitous and acts through Gβγ to inhibit Ca2+ entry, or directly at SNARE complexes to inhibit Ca2+-dependent synaptotagmin-SNARE complex interactions. At CA1-su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a38cf78618b0f75cc9283e484bc11074
https://doi.org/10.1101/2020.11.12.362491
https://doi.org/10.1101/2020.11.12.362491
Publikováno v:
Cell Reports. 38:110255