Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zack Nash"'
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5290 (2009)
Previously we have shown that compacted DNA nanoparticles can drive high levels of transgene expression after subretinal injection in the mouse eye. Here we delivered compacted DNA nanoparticles containing a therapeutic gene to the retinas of a mouse
Externí odkaz:
https://doaj.org/article/ca011eb9110643069edecc239df41407
Publikováno v:
The FASEB Journal. 24:1178-1191
The purpose of the present study was to test the therapeutic efficiency and safety of compacted-DNA nanoparticle-mediated gene delivery into the subretinal space of a juvenile mouse model of retinitis pigmentosa. Nanoparticles containing the mouse op
Autor:
Steven J. Fliesler, Zack Nash, Jeff Skaggs, Muna I. Naash, B.A. Nagel, Alexander B. Quiambao, Rafal Farjo
Publikováno v:
The Journal of Cell Biology
It is commonly assumed that photoreceptor (PR) outer segment (OS) morphogenesis is reliant upon the presence of peripherin/rds, hereafter termed Rds. In this study, we demonstrate a differential requirement of Rds during rod and cone OS morphogenesis
Publikováno v:
Journal of Vascular Surgery. 63:232S
Publikováno v:
Advances in experimental medicine and biology. 723
Publikováno v:
Retinal Degenerative Diseases ISBN: 9781461406303
ROM-1 (rod outer segment membrane protein-1) is a tetraspanin protein present in the outer segment (OS) rims of rod and cone photoreceptors. It shares many common features with other tetraspanins, including a large intradiscal loop which contains sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98139310b0bb472e941ff1aa0d88e2cd
https://doi.org/10.1007/978-1-4614-0631-0_80
https://doi.org/10.1007/978-1-4614-0631-0_80
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5290 (2009)
PLoS ONE
PLoS ONE
Previously we have shown that compacted DNA nanoparticles can drive high levels of transgene expression after subretinal injection in the mouse eye. Here we delivered compacted DNA nanoparticles containing a therapeutic gene to the retinas of a mouse
Autor:
Zack Nash, Muna I. Naash
Publikováno v:
Retinal Degenerative Diseases ISBN: 9780387284644
Genomic analysis, from patients with retinal diseases such as retinitis pigmentosa (RP) and congenital night blindness (CNB), has provided convincing evidence that various subtypes of retinal diseases can result from mutations in the gene encoding ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b4ff37ac9bb3fa0210b5735b97abc7
https://doi.org/10.1007/0-387-32442-9_19
https://doi.org/10.1007/0-387-32442-9_19
Autor:
Mark J. Cooper, Zack Nash, Ron M. Ballard, Muna I. Naash, Jeff Skaggs, Alexander B. Quiambao, Rafal Farjo
Publikováno v:
Molecular Therapy. 13
Top of pageAbstract The present study was undertaken to determine the efficacy of DNA nanotechnology as an effective therapeutic strategy for eye diseases; particularly those associated with loss-of-function mutations in the retina and retinal pigmen
Autor:
Mark E. McClellan, Steven J. Fliesler, Michael H. Elliott, Nobuaki Takemori, Muna I. Naash, Zack Nash
Publikováno v:
Journal of Neurochemistry. :071018045431009
Membrane heterogeneity plays a significant role in regulating signal transduction and other cellular activities. We examined the protein and lipid components associated with the detergent-resistant membrane (DRM) fractions from retinal rod outer segm