Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zachary Tokuno"'
Autor:
Gepoliano Chaves, Rıfat Emrah Özel, Namrata V Rao, Hana Hadiprodjo, Yvonne Da Costa, Zachary Tokuno, Nader Pourmand
Publikováno v:
Heliyon, Vol 3, Iss 8 (2017)
Huntington’s Disease (HD) is a neurodegenerative disorder caused by an expansion in a CAG-tri-nucleotide repeat that introduces a poly-glutamine stretch into the huntingtin protein (mHTT). Mutant huntingtin (mHTT) has been associated with several p
Externí odkaz:
https://doaj.org/article/2f8d7433e3ea42f793e32d02f2c426cf
Autor:
Jeremy W. Linsley, Drew A. Linsley, Josh Lamstein, Gennadi Ryan, Kevan Shah, Nicholas A. Castello, Viral Oza, Jaslin Kalra, Shijie Wang, Zachary Tokuno, Ashkan Javaherian, Thomas Serre, Steven Finkbeiner
Publikováno v:
Science Advances
Science Advances, vol 7, iss 50
Science Advances, vol 7, iss 50
Description
High-throughput microscopy has outpaced analysis; biomarker-optimized CNNs are a generalizable, fast, and interpretable solution.
Cellular events underlying neurodegenerative disease may be captured by longitudinal live microsco
High-throughput microscopy has outpaced analysis; biomarker-optimized CNNs are a generalizable, fast, and interpretable solution.
Cellular events underlying neurodegenerative disease may be captured by longitudinal live microsco
Autor:
Mara Dierssen, Julia Kaye, Jen Leddy, Steven Finkbeiner, Nicole Bellini, Stephanie Lam, Mariya, Melanie H. Cobb, Linus Manubens-Gil, Zachary Tokuno, Keili Prenton
Changes to neuronal morphology and loss of neurites and synaptic connections can be an important early indicator of neurological diseases, and a pathognomonic sign of neurodevelopmental disorders. These changes are typically detectable by microscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f8f89fb1f61c5ed74d71e842fb7799
https://doi.org/10.1101/2021.04.23.441035
https://doi.org/10.1101/2021.04.23.441035
Autor:
Jeremy W. Linsley, Ashkan Javaherian, Josh Lamstein, Viral Oza, Steven Finkbeiner, Gennadi Ryan, Zachary Tokuno, Drew Linsley, Shijie Wang, Thomas Serre, Kevan Shah, Jaslin Kalra, Nicholas A. Castello
Cell death is an essential process in biology that must be accounted for in live microscopy experiments. Nevertheless, cell death is difficult to detect without perturbing experiments with stains, dyes or biosensors that can bias experimental outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99f9521d2fa22b89e646e6c84bcbaed
https://doi.org/10.1101/2020.08.04.237032
https://doi.org/10.1101/2020.08.04.237032