Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Zachary S. Buchwald"'
Autor:
Brendan L.C. Kinney, Brianna Brammer, Vikash Kansal, Connor J. Parrish, Haydn T. Kissick, Yuan Liu, Nabil F. Saba, Zachary S. Buchwald, Mark W. El-Deiry, Mihir R. Patel, Brian J. Boyce, Azeem S. Kaka, Jennifer H. Gross, H. Michael Baddour, Amy Y. Chen, Nicole C. Schmitt
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
T lymphocytes expressing CD57 and lacking costimulatory receptors CD27/CD28 have been reported to accumulate with aging, chronic infection, and cancer. These cells are described as senescent, with inability to proliferate but enhanced cytolytic and c
Externí odkaz:
https://doaj.org/article/3967eb4b36174a4b8c3720cf04420d75
Autor:
Vikash Kansal, Brendan L. C. Kinney, Srijayaprakash Uppada, Nabil F. Saba, William A. Stokes, Zachary S. Buchwald, Nicole C. Schmitt
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 13958-13965 (2023)
Abstract Inhibitors of apoptosis proteins (IAPs) inhibit the intrinsic and extrinsic cell death pathways, promoting cell survival. Antagonists of these pathways are under study as anti‐cancer therapeutics. A high proportion of head and neck squamou
Externí odkaz:
https://doaj.org/article/b0c759795a2b40de967a38d3dd103122
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The human skin hosts millions of bacteria, fungi, archaea, and viruses. These skin microbes play a crucial role in human immunological and physiological functions, as well as the development of skin diseases, including cancer when the balance between
Externí odkaz:
https://doaj.org/article/74a8d16a0e064201be9c1731ec6acf01
Autor:
David G. Wallington, MS, Arif S. Rashid, MD, Zachary S. Buchwald, MD, PhD, Lisa J. Sudmeier, MD, PhD, Mohammad K. Khan, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 3, Pp 503-510 (2020)
Externí odkaz:
https://doaj.org/article/5c4a2bf604ac4ef99b186c0151bfee24
Autor:
Roshan S. Prabhu, MD, MS, Brandon E. Turner, MD, Anthony L. Asher, MD, Samuel R. Marcrom, MD, John B. Fiveash, MD, Paul M. Foreman, MD, Robert H. Press, MD, Zachary S. Buchwald, MD, PhD, Walter J. Curran, Jr., MD, Kirtesh R. Patel, MD, William G. Breen, MD, Paul D. Brown, MD, Krishan R. Jethwa, MD, Inga S. Grills, MD, Jessica D. Arden, MD, Lauren M. Foster, BS, Matthew A. Manning, MD, Zachary K. Vaslow, MD, Stuart H. Burri, MD, Scott G. Soltys, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 2, Pp 100644- (2021)
Purpose: Postoperative stereotactic radiosurgery (SRS) is associated with up to 30% risk of subsequent leptomeningeal disease (LMD). Radiographic patterns of LMD (classical sugarcoating [cLMD] vs. nodular [nLMD]) in this setting has been shown to be
Externí odkaz:
https://doaj.org/article/b050947fe2d94be3a0ae4260b1afa124
Autor:
Roshan S. Prabhu, MD, MS, Matthew C. Ward, MD, John H. Heinzerling, MD, Christopher D. Corso, MD, PhD, Zachary S. Buchwald, MD, PhD, Reshika Dhakal, MD, Anthony L. Asher, MD, Ashley L. Sumrall, MD, Stuart H. Burri, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 1, Pp 100577- (2021)
Purpose: Previous trials have shown no benefit for radiation therapy (RT) dose escalation when RT is given as adjuvant monotherapy for infiltrative low-grade glioma (LGG). However, the current standard of care for high-risk LGG is RT with concurrent
Externí odkaz:
https://doaj.org/article/8ac56b928f424865810587d4fc3acdd4
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11061 (2021)
Radiotherapy has been used for more than a hundred years to cure or locally control tumors. Regression of tumors outside of the irradiated field was occasionally observed and is known as the abscopal effect. However, the occurrence of systemic anti-t
Externí odkaz:
https://doaj.org/article/dd5b4534f95144aaa507db4a7e677815
Autor:
Arjun Khunger, Zachary S. Buchwald, Michael Lowe, Mohammad K. Khan, Keith A. Delman, Ahmad A. Tarhini
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Locally/regionally advanced melanoma confers a major challenge in terms of surgical and medical management. Surgical treatment carries the risks of surgical morbidities and potential complications that could be lasting. In addition, these patients co
Externí odkaz:
https://doaj.org/article/bf8634c2cd224b56b0f09af78e3cd381
Autor:
Zachary S. Buchwald, Jacob Wynne, Tahseen H. Nasti, Simeng Zhu, Waleed F. Mourad, Weisi Yan, Seema Gupta, Samir N. Khleif, Mohammad K. Khan
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The combination of radiation and immunotherapy is currently an exciting avenue of pre-clinical and clinical investigation. The synergy between these two treatment modalities has the potential to expand the role of radiation from a purely local therap
Externí odkaz:
https://doaj.org/article/18529fbf63614edfa15b79c8420eb224
Autor:
Kirtesh R. Patel, Anthony Martinez, John M. Stahl, Suzanna J. Logan, Adam J. Perricone, Matthew J. Ferris, Zachary S. Buchwald, Mudit Chowdhary, Keith A. Delman, David K. Monson, Shervin V. Oskouei, Nicholas B. Reimer, Kenneth Cardona, Mark A. Edgar, Karen D. Godette
Publikováno v:
OncoImmunology, Vol 7, Iss 7 (2018)
Soft tissue sarcomas (STS) have minimal expression of PD-L1, a biomarker for PD-1 therapy efficacy. Radiotherapy (RT) has been shown to increase PD-L1 expression pre-clinically. We examined the expression of PD-L1, pre- and post-RT, in 46 Stage II-II
Externí odkaz:
https://doaj.org/article/2d90a55e3539419db69bd3f70ffe1f1a