Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Zachary S, Buchwald"'
Autor:
Caroline S. Jansen, Meghana S. Pagadala, Maria A. Cardenas, Roshan S. Prabhu, Subir Goyal, Chengjing Zhou, Prasanthi Chappa, BaoHan T. Vo, Chengyu Ye, Benjamin Hopkins, Jim Zhong, Adam Klie, Taylor Daniels, Maedot Admassu, India Green, Neil T. Pfister, Stewart G. Neill, Jeffrey M. Switchenko, Nataliya Prokhnevska, Kimberly B. Hoang, Mylin A. Torres, Suzanna Logan, Jeffrey J. Olson, Edjah K. Nduom, Luke del Balzo, Kirtesh Patel, Stuart H. Burri, Anthony L. Asher, Scott Wilkinson, Ross Lake, Aparna H. Kesarwala, Kristin A. Higgins, Pretesh Patel, Vishal Dhere, Adam G. Sowalsky, Hannah Carter, Mohammad K. Khan, Haydn Kissick, Zachary S. Buchwald
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Enhancing the efficacy of immunotherapy in brain metastases (BrM) requires an improved understanding of the immune composition of BrM and how this is affected by radiation and dexamethasone. Our two-arm pilot study (NCT04895592) allocated 26
Externí odkaz:
https://doaj.org/article/f2e15d60d8c7479ea6d0d2f87a5326a2
Autor:
Rahul K Nayak, Zachary S Buchwald, Meili Aiello, Laneisha Marielis Maldonado, Tarralyn Y Clark, Andres Chang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Immune checkpoint blockade (ICB) therapies are one of the greatest advances in the history of cancer care and are now commonly used in the management of many different malignancies. However, much remains unknown about the factors that affect the effi
Externí odkaz:
https://doaj.org/article/788aa7299de443719a4c3dae1bf3893c
Autor:
Brendan L.C. Kinney, Brianna Brammer, Vikash Kansal, Connor J. Parrish, Haydn T. Kissick, Yuan Liu, Nabil F. Saba, Zachary S. Buchwald, Mark W. El-Deiry, Mihir R. Patel, Brian J. Boyce, Azeem S. Kaka, Jennifer H. Gross, H. Michael Baddour, Amy Y. Chen, Nicole C. Schmitt
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
T lymphocytes expressing CD57 and lacking costimulatory receptors CD27/CD28 have been reported to accumulate with aging, chronic infection, and cancer. These cells are described as senescent, with inability to proliferate but enhanced cytolytic and c
Externí odkaz:
https://doaj.org/article/3967eb4b36174a4b8c3720cf04420d75
Autor:
Haydn Kissick, Viraj A Master, Mehmet A Bilen, Zachary S Buchwald, Mohammad K Khan, Caroline S Jansen, Michael C Lowe, Jimmy S Patel, Yena Woo, Amber Draper, Jennifer W Carlisle, Pasquale F Innominato, Francis A Lévi, Layla Dhabaan, David C Qian
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Recent studies have demonstrated that earlier time-of-day infusion of immune checkpoint inhibitors (ICIs) is associated with longer progression-free survival (PFS) and overall survival (OS) among patients with metastatic melanoma and non-s
Externí odkaz:
https://doaj.org/article/daa2d9d9173340d48a63f3613635074f
Autor:
Vikash Kansal, Brendan L. C. Kinney, Srijayaprakash Uppada, Nabil F. Saba, William A. Stokes, Zachary S. Buchwald, Nicole C. Schmitt
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 13958-13965 (2023)
Abstract Inhibitors of apoptosis proteins (IAPs) inhibit the intrinsic and extrinsic cell death pathways, promoting cell survival. Antagonists of these pathways are under study as anti‐cancer therapeutics. A high proportion of head and neck squamou
Externí odkaz:
https://doaj.org/article/b0c759795a2b40de967a38d3dd103122
Autor:
Chrystal Paulos, Gregory B Lesinski, Zachary S Buchwald, Nabil F Saba, Vikash Kansal, Andre J Burnham, Brendan L C Kinney, Nicole C Schmitt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Anti-PD-1 immune checkpoint blockade is approved for first-line treatment of recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), but few patients respond. Statin drugs (HMG-CoA reductase inhibitors) are associated with supe
Externí odkaz:
https://doaj.org/article/8c89bacdb70947e88cb21a0488441844
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The human skin hosts millions of bacteria, fungi, archaea, and viruses. These skin microbes play a crucial role in human immunological and physiological functions, as well as the development of skin diseases, including cancer when the balance between
Externí odkaz:
https://doaj.org/article/74a8d16a0e064201be9c1731ec6acf01
Autor:
David G. Wallington, MS, Arif S. Rashid, MD, Zachary S. Buchwald, MD, PhD, Lisa J. Sudmeier, MD, PhD, Mohammad K. Khan, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 3, Pp 503-510 (2020)
Externí odkaz:
https://doaj.org/article/5c4a2bf604ac4ef99b186c0151bfee24
Autor:
Roshan S. Prabhu, MD, MS, Brandon E. Turner, MD, Anthony L. Asher, MD, Samuel R. Marcrom, MD, John B. Fiveash, MD, Paul M. Foreman, MD, Robert H. Press, MD, Zachary S. Buchwald, MD, PhD, Walter J. Curran, Jr., MD, Kirtesh R. Patel, MD, William G. Breen, MD, Paul D. Brown, MD, Krishan R. Jethwa, MD, Inga S. Grills, MD, Jessica D. Arden, MD, Lauren M. Foster, BS, Matthew A. Manning, MD, Zachary K. Vaslow, MD, Stuart H. Burri, MD, Scott G. Soltys, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 2, Pp 100644- (2021)
Purpose: Postoperative stereotactic radiosurgery (SRS) is associated with up to 30% risk of subsequent leptomeningeal disease (LMD). Radiographic patterns of LMD (classical sugarcoating [cLMD] vs. nodular [nLMD]) in this setting has been shown to be
Externí odkaz:
https://doaj.org/article/b050947fe2d94be3a0ae4260b1afa124
Autor:
Roshan S. Prabhu, MD, MS, Matthew C. Ward, MD, John H. Heinzerling, MD, Christopher D. Corso, MD, PhD, Zachary S. Buchwald, MD, PhD, Reshika Dhakal, MD, Anthony L. Asher, MD, Ashley L. Sumrall, MD, Stuart H. Burri, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 1, Pp 100577- (2021)
Purpose: Previous trials have shown no benefit for radiation therapy (RT) dose escalation when RT is given as adjuvant monotherapy for infiltrative low-grade glioma (LGG). However, the current standard of care for high-risk LGG is RT with concurrent
Externí odkaz:
https://doaj.org/article/8ac56b928f424865810587d4fc3acdd4