Výsledky vyhledávání - "Zachary R. Welch"

Characterization of the Cellular Output of a Point-of-Care Device and the Implications for Addressing Critical Limb Ischemia

Autor: Matthew L. Tan, William J. King, Jennifer E. Woodell-May, Michael P. Murphy, Zachary R. Welch, James M. McKale, Matthew J. Swift

Publikováno v: BioResearch Open Access, Vol 4, Iss 1, Pp 417-424 (2015)
BioResearch Open Access

Critical limb ischemia (CLI) is a terminal disease with high morbidity and healthcare costs due to limb loss. There are no effective medical therapies for patients with CLI to prevent amputation. Cell-based therapies are currently being investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71aa2f901defbb67aa96b7e0593af8ac
https://doi.org/10.1089/biores.2015.0006

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Autologous protein solution inhibits MMP-13 production by IL-1β and TNFα-stimulated human articular chondrocytes

Autor: Jennifer E. Woodell-May, Krista O'shaughnessey, Andrea M. Matuska, Zachary R. Welch, Megan Oyster, Jacy C. Hoeppner

Publikováno v: Journal of Orthopaedic Research. 29:1320-1326

Catabolic inflammatory cytokines are prevalent in osteoarthritis (OA). The purpose of this study was to evaluate an autologous protein solution (APS) as a potential chondroprotective agent for OA therapy. APS was prepared from platelet-rich plasma (P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84d7a1e5cd4c74e3ce27ace3a1bcd448
https://doi.org/10.1002/jor.21384

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Role of Rho kinase in sphingosine 1-phosphate-mediated endothelial and smooth muscle cell migration and differentiation

Autor: Zachary R. Welch, Kevin A. Harvey, Daniel Sliva, Rafat A. Siddiqui

Publikováno v: Molecular and Cellular Biochemistry. 342:7-19

The role of sphingosine 1-phosphate (S1P)-induced Rho kinase (ROCK) activation in the angiogenic responses of pulmonary artery-derived endothelial cells (PAEC) and smooth muscle cells (PASMC) was examined. S1P, a biologically active phospholipid that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8132e13060de8dc96ef98241c39ca670
https://doi.org/10.1007/s11010-010-0461-2

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Omega-3 polyunsaturated fatty acids attenuate breast cancer growth through activation of a neutral sphingomyelinase-mediated pathway

Autor: Min Wu, Nargiz Ruzmetov, Kim Jackson, Gary P. Zaloga, William Stillwell, Kevin A. Harvey, Laura A. Sech, Zachary R. Welch, Rafat A. Siddiqui

Publikováno v: International journal of cancer. 117(3)

The effect of fish oils and their active omega-3 fatty acid constituents, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), were investigated on breast cancer growth. In in vivo experiments, mice were fed diets that were rich in either omeg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e525a886c5659d5414de45eb5cb1c2
https://pubmed.ncbi.nlm.nih.gov/15900589

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Concentration of Neurotransmitter and Neurotrophic Factors in Platelet Rich Plasma

Autor: Matthew J. Swift, Jennifer E. Woodell-May, Jesse A. Greene, Zachary R. Welch

Publikováno v: Blood. 108:3914-3914

Use of autologous platelet rich plasma (PRP) is emerging in a variety of clinical settings. Although the desired effects of PRP application vary across indications, the common mechanism of action is the up-regulation of the healing response at the si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::976d27bb4d37687d3914d30c25e8aa77
https://doi.org/10.1182/blood.v108.11.3914.3914

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