Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zachary R. Moore"'
Autor:
Anthony F. Yu, Zachary R. Moore, Chaya S. Moskowitz, Jennifer E. Liu, Chau T. Dang, Lakshmi Ramanathan, Kevin C. Oeffinger, Richard M. Steingart, Adam M. Schmitt
Publikováno v:
JAMA Cardiology.
ImportanceCancer therapy–related cardiac dysfunction (CTRCD) is a potentially serious cardiotoxicity of treatments for ERBB2-positive breast cancer (formerly HER2). Identifying early biomarkers of cardiotoxicity could facilitate an individualized a
Autor:
Rolf A. Brekken, Diego H. Castrillon, Agnieszka Witkiewicz, Huamin Wang, Hiromi Yanagisawa, David A. Boothman, Zachary R. Moore, Christopher M. Wright, Jason E. Toombs, Mary Topalovski, Miao Wang
Fbln5 and α5β1 integrin expression pattern in mouse and human (S1); Characterization of KIC and KPC mice (S2); Examination of ROS levels in normal pancreas and NAC-treated KIC and RGE KIC tumors (S3); Reduced microvessel density (MVD) in RGE KIC an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f02f365b30df5db83e68422d13141e
https://doi.org/10.1158/0008-5472.22406943
https://doi.org/10.1158/0008-5472.22406943
Autor:
Rolf A. Brekken, Diego H. Castrillon, Agnieszka Witkiewicz, Huamin Wang, Hiromi Yanagisawa, David A. Boothman, Zachary R. Moore, Christopher M. Wright, Jason E. Toombs, Mary Topalovski, Miao Wang
Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3af3234c18bccf49f1c68cfadf6c90
https://doi.org/10.1158/0008-5472.22406940
https://doi.org/10.1158/0008-5472.22406940
Autor:
Rolf A. Brekken, Diego H. Castrillon, Agnieszka Witkiewicz, Huamin Wang, Hiromi Yanagisawa, David A. Boothman, Zachary R. Moore, Christopher M. Wright, Jason E. Toombs, Mary Topalovski, Miao Wang
Elevated oxidative stress is an aberration seen in many solid tumors, and exploiting this biochemical difference has the potential to enhance the efficacy of anticancer agents. Homeostasis of reactive oxygen species (ROS) is important for normal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158de5ca2c41f78828541ad267176093
https://doi.org/10.1158/0008-5472.c.6507195
https://doi.org/10.1158/0008-5472.c.6507195
Randomized Phase 2 Placebo-Controlled Trial of Nintedanib for the Treatment of Radiation Pneumonitis
Autor:
Andreas Rimner, Zachary R. Moore, Stephanie Lobaugh, Alexander Geyer, Daphna Y. Gelblum, Raja-Elie E. Abdulnour, Annemarie F. Shepherd, Narek Shaverdian, Abraham J. Wu, John Cuaron, Jamie E. Chaft, Marjorie G. Zauderer, Juliana Eng, Gregory J. Riely, Charles M. Rudin, Nicholas Vander Els, Mohit Chawla, Megan McCune, Henry Li, David R. Jones, Dennis M. Sopka, Charles B. Simone, Raymond Mak, Gerald L. Weinhouse, Zhongxing Liao, Daniel R. Gomez, Zhigang Zhang, Paul K. Paik
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics.
Autor:
Achraf Shamseddine, Suchit H. Patel, Valery Chavez, Zachary R. Moore, Mutayyaba Adnan, Melody Di Bona, Jun Li, Chau T. Dang, Lakshmi V. Ramanathan, Kevin C. Oeffinger, Jennifer E. Liu, Richard M. Steingart, Alessandra Piersigilli, Nicholas D. Socci, Angel T. Chan, Anthony F. Yu, Samuel F. Bakhoum, Adam M. Schmitt
Late cardiac toxicity is a potentially lethal complication of cancer therapy, yet the pathogenic mechanism remains largely unknown, and few treatment options exist. Here we report DNA damaging agents such as radiation and anthracycline chemotherapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2237953230099115119e589a571c4453
https://doi.org/10.1101/2021.09.26.461865
https://doi.org/10.1101/2021.09.26.461865
Autor:
Saad A. Khan, Jennifer L Shah, David J. Sher, Lucien A. Nedzi, Zachary R. Moore, Baran D. Sumer, Nhat-Long Lam Pham, Andrew T. Day
Publikováno v:
Journal of pain and symptom management. 57(4)
Context Radiotherapy is highly effective for treating squamous cell carcinoma of the head and neck but is often associated with significant toxicities and severe morbidity. Unplanned emergency department (ED) visits and hospitalizations are common du
Autor:
Zachary R. Moore, Praveen L. Patidar, Edward A. Motea, John D. Minna, Jessica A. Kilgore, Ying Dong, Noelle S. Williams, Farjana J. Fattah, Rebecca Kusko, Erik A. Bey, Molly A. Silvers, Michael Peyton, Venetia R. Sarode, Xiumei Huang, Agnieszka Cholka, David A. Boothman, David E. Gerber, Muhammad Shaalan Beg, Xian Jin Xie, Jingsheng Yan, Glenda G. Anderson, Jun Yao, Yoonjeong Cha, Gaurab Chakrabarti
Therapeutic drugs that block DNA repair, including poly(ADP-ribose) polymerase (PARP) inhibitors, fail due to lack of tumor-selectivity. When PARP inhibitors and β-lapachone are combined, synergistic antitumor activity results from sustained NAD(P)H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e317c066f3e18b53dd11f976c6a12d
https://europepmc.org/articles/PMC5161231/
https://europepmc.org/articles/PMC5161231/
Autor:
Diego H. Castrillon, Miao Wang, Agnieszka K. Witkiewicz, Hiromi Yanagisawa, Jason E. Toombs, Christopher M. Wright, Rolf A. Brekken, Mary Topalovski, Zachary R. Moore, David A. Boothman, Huamin Wang
Elevated oxidative stress is an aberration seen in many solid tumors, and exploiting this biochemical difference has the potential to enhance the efficacy of anticancer agents. Homeostasis of reactive oxygen species (ROS) is important for normal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45ae2b5d3b672323a4bedc3c4f9e7ce
https://europepmc.org/articles/PMC4668215/
https://europepmc.org/articles/PMC4668215/
Publikováno v:
Journal of drug targeting. 23(7-8)
Current cancer chemotherapy lacks specificity and is limited by undesirable toxic side-effects, as well as a high rate of recurrence. Nanotechnology has the potential to offer paradigm-shifting solutions to improve the outcome of cancer diagnosis and