Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Zachary Pincus"'
Autor:
Nicholas O. Jensen, Brooke Burris, Lili Zhou, Hunter Yamada, Catrina Reyes, Zachary Pincus, Mayssa H. Mokalled
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Adult zebrafish are capable of anatomical and functional recovery following severe spinal cord injury. Axon growth, glial bridging and adult neurogenesis are hallmarks of cellular regeneration during spinal cord repair. However, the correlation betwe
Externí odkaz:
https://doaj.org/article/a6c5fbfd163a4037829612087bf68410
Publikováno v:
eLife, Vol 10 (2021)
Across species, lifespan is highly variable among individuals within a population. Even genetically identical Caenorhabditis elegans reared in homogeneous environments are as variable in lifespan as outbred human populations. We hypothesized that per
Externí odkaz:
https://doaj.org/article/22fc1bb55ca940b4aa9f6ebd7d416072
Autor:
Ambroise Lambert, Aster Vanhecke, Anna Archetti, Seamus Holden, Felix Schaber, Zachary Pincus, Michael T. Laub, Erin Goley, Suliana Manley
Publikováno v:
iScience, Vol 4, Iss , Pp 180-189 (2018)
Summary: Rod-shaped bacteria typically grow first via sporadic and dispersed elongation along their lateral walls and then via a combination of zonal elongation and constriction at the division site to form the poles of daughter cells. Although const
Externí odkaz:
https://doaj.org/article/33bd07e9800c4bbdb90ec9090e9aa814
Autor:
Evgeniy R. Galimov, Rosina E. Pryor, Sarah E. Poole, Alexandre Benedetto, Zachary Pincus, David Gems
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2730-2741 (2018)
Summary: Organismal death is a process of systemic collapse whose mechanisms are less well understood than those of cell death. We previously reported that death in C. elegans is accompanied by a calcium-propagated wave of intestinal necrosis, marked
Externí odkaz:
https://doaj.org/article/c600758ff81a4a5a8801f350cb0c9c7b
Autor:
Yuan Zhao, Ann F. Gilliat, Matthias Ziehm, Mark Turmaine, Hongyuan Wang, Marina Ezcurra, Chenhao Yang, George Phillips, David McBay, William B. Zhang, Linda Partridge, Zachary Pincus, David Gems
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that ar
Externí odkaz:
https://doaj.org/article/71789ec218844f8ab9c0ea0c9fa9e546
Autor:
Cassandra Coburn, Erik Allman, Parag Mahanti, Alexandre Benedetto, Filipe Cabreiro, Zachary Pincus, Filip Matthijssens, Caroline Araiz, Abraham Mandel, Manolis Vlachos, Sally-Anne Edwards, Grahame Fischer, Alexander Davidson, Rosina E Pryor, Ailsa Stevens, Frank J Slack, Nektarios Tavernarakis, Bart P Braeckman, Frank C Schroeder, Keith Nehrke, David Gems
Publikováno v:
PLoS Biology, Vol 11, Iss 7, p e1001613 (2013)
For cells the passage from life to death can involve a regulated, programmed transition. In contrast to cell death, the mechanisms of systemic collapse underlying organismal death remain poorly understood. Here we present evidence of a cascade of cel
Externí odkaz:
https://doaj.org/article/b5384d0af3b54c4ea29373242cae6123
Autor:
Patricia T Yam, Zachary Pincus, Gagan D Gupta, Mikhail Bashkurov, Frédéric Charron, Laurence Pelletier, David R Colman
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79679 (2013)
N-cadherin is a cell adhesion molecule which is enriched at synapses. Binding of N-cadherin molecules to each other across the synaptic cleft has been postulated to stabilize adhesion between the presynaptic bouton and the postsynaptic terminal. N-ca
Externí odkaz:
https://doaj.org/article/6240d76090b9402c880e53dc94d84035
Autor:
Laura K Sycuro, Timna J Wyckoff, Jacob Biboy, Petra Born, Zachary Pincus, Waldemar Vollmer, Nina R Salama
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002603 (2012)
Helical cell shape of the gastric pathogen Helicobacter pylori has been suggested to promote virulence through viscosity-dependent enhancement of swimming velocity. However, H. pylori csd1 mutants, which are curved but lack helical twist, show normal
Externí odkaz:
https://doaj.org/article/eb42816c8db5439b89ff1fb6480eb936
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002306 (2011)
Neither genetic nor environmental factors fully account for variability in individual longevity: genetically identical invertebrates in homogenous environments often experience no less variability in lifespan than outbred human populations. Such vari
Externí odkaz:
https://doaj.org/article/6546810beb2c4d08b94740e8b88c0977
Autor:
Catherine I Lacayo, Zachary Pincus, Martijn M VanDuijn, Cyrus A Wilson, Daniel A Fletcher, Frank B Gertler, Alex Mogilner, Julie A Theriot
Publikováno v:
PLoS Biology, Vol 5, Iss 9, p e233 (2007)
Variations in cell migration and morphology are consequences of changes in underlying cytoskeletal organization and dynamics. We investigated how these large-scale cellular events emerge as direct consequences of small-scale cytoskeletal molecular ac
Externí odkaz:
https://doaj.org/article/d669b8993fab436e85b6f93a586c5391