Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zachary M. Zigmond"'
Autor:
Miguel G. Rojas, Zachary M. Zigmond, Simone Pereira-Simon, Nieves Santos Falcon, Maya Suresh Kumar, Filipe F. Stoyell-Conti, Christina Kosanovic, Anthony J. Griswold, Alghidak Salama, Xiaofeng Yang, Marwan Tabbara, Roberto I. Vazquez-Padron, Laisel Martinez
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/ff87a5c7f0a74beab6887cb1d7d5c447
Autor:
Miguel G. Rojas, Simone Pereira-Simon, Zachary M. Zigmond, Javier Varona Santos, Mikael Perla, Nieves Santos Falcon, Filipe F. Stoyell-Conti, Alghidak Salama, Xiaofeng Yang, Xiaochun Long, Juan C. Duque, Loay H. Salman, Marwan Tabbara, Laisel Martinez, Roberto I. Vazquez-Padron
Publikováno v:
Cells, Vol 13, Iss 10, p 793 (2024)
Arteries and veins develop different types of occlusive diseases and respond differently to injury. The biological reasons for this discrepancy are not well understood, which is a limiting factor for the development of vein-targeted therapies. This s
Externí odkaz:
https://doaj.org/article/a69769cc73884282a9e2c00bf25cb441
Autor:
Xochilt Labissiere, Zachary M. Zigmond, Akshara Challa, Christopher Montoya, Karen Manzur-Pineda, Amalia Abraham, Marwan Tabbara, Alghidak Salama, Yue Pan, Loay H. Salman, Xiaofeng Yang, Roberto I. Vazquez-Padron, Laisel Martinez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundChronic kidney disease (CKD) is a highly comorbid condition with significant effects on vascular health and remodeling. Upper extremity veins are important in end-stage kidney disease (ESKD) due to their potential use to create vascular acc
Externí odkaz:
https://doaj.org/article/6f1a6f475038423d8ecc36e106d5ee35
Autor:
Lei Song, Laisel Martinez, Zachary M. Zigmond, Diana R. Hernandez, Roberta M. Lassance-Soares, Guillermo Selman, Roberto I. Vazquez-Padron
Publikováno v:
PeerJ, Vol 5, p e3418 (2017)
Background c-Kit is a receptor tyrosine kinase present in multiple cell types, including vascular smooth muscle cells (SMC). However, little is known about how c-Kit influences SMC biology and vascular pathogenesis. Methods High-throughput microarray
Externí odkaz:
https://doaj.org/article/a1a3803722bf4c2aa838ab683798d6f1
Autor:
Laisel Martinez, Miguel G. Rojas, Marwan Tabbara, Simone Pereira-Simon, Nieves Santos Falcon, Mohd Ahmar Rauf, Akshara Challa, Zachary M. Zigmond, Anthony J. Griswold, Juan C. Duque, Roberta M. Lassance-Soares, Omaida C. Velazquez, Loay H. Salman, Roberto I. Vazquez-Padron
Publikováno v:
Kidney Int Rep
INTRODUCTION: The molecular transformation of the human preaccess vein after arteriovenous fistula (AVF) creation is poorly understood. This limits our ability to design efficacious therapies to improve maturation outcomes. METHODS: Bulk RNA sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6032a9ae25c7316de0f3f485d80a1bfb
https://europepmc.org/articles/PMC10105062/
https://europepmc.org/articles/PMC10105062/
Autor:
Laisel Martinez, Lei Song, Zachary M. Zigmond, Roberta M. Lassance-Soares, Omaida C. Velazquez, Roberto I. Vazquez-Padron
Publikováno v:
Atherosclerosis. 324:133-140
Background and aims Increased receptor tyrosine kinase (RTK) activity has been historically linked to atherosclerosis. Paradoxically, we recently found that global deficiency in c-Kit function increased atherosclerosis in hyperlipidemic mice. This st
Autor:
Omaida C. Velazquez, Nieves Santos Falcon, Vineet Gupta, Diana R. Hernandez, Xiaobo Li, Serene A. Shehadeh, Zachary M. Zigmond, Gioser Ramos-Echazabal, Hafeez Faridi, Roberto I. Vazquez-Padron, Laisel Martinez
Publikováno v:
J Immunol
Pharmacological activation of integrin CD11b/CD18 (αMβ2, Mac-1, and CR3) shows anti-inflammatory benefits in a variety of animal models of human disease, and it is a novel therapeutic strategy. Reasoning that genetic models can provide an orthogona
Autor:
Roberta M. Lassance-Soares, Diana R. Hernandez, Roberto I. Vazquez-Padron, Boris L Rodriguez, Zachary M. Zigmond, Miguel G. Rojas, Laisel Martinez
Publikováno v:
Biochem Biophys Res Commun
Introduction Receptor tyrosine kinases have been implicated in various vascular remodeling processes and cardiovascular disease. However, their role in the regulation of vascular tone is poorly understood. Herein, we evaluate the contribution of c-Ki
Autor:
Gustavo Falero-Diaz, Catarina de A. Barboza, Felipe Pires, Maeva Fanchin, Jingjing Ling, Zachary M. Zigmond, Anthony J. Griswold, Laisel Martinez, Roberto I. Vazquez-Padron, Omaida C. Velazquez, Roberta M. Lassance-Soares
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Monocytes, which play an important role in arteriogenesis, can build immunologic memory by a functional reprogramming that modifies their response to a second challenge. This process, called trained immunity, is evoked by insults that shif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd20c049eadfdb6f40a843d9939548a
https://europepmc.org/articles/PMC8792358/
https://europepmc.org/articles/PMC8792358/
Autor:
Lei Song, Alghidak Salama, Keith A. Webster, Roberto I. Vazquez-Padron, Zachary M. Zigmond, Omaida C. Velazquez, Alejandro E. Macias, Zhao-Jun Liu, Laisel Martinez, Roberta M. Lassance-Soares
Publikováno v:
Am J Physiol Heart Circ Physiol
Atherosclerosis is the most common underlying cause of cardiovascular morbidity and mortality worldwide. c-Kit (CD117) is a member of the receptor tyrosine kinase family, which regulates differentiation, proliferation, and survival of multiple cell t