Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zachary M Nash"'
Autor:
Liliana S McKay, Alexa R Spandrio, Richard M Johnson, M Ashley Sobran, Sara A Marlatt, Katlyn B Mote, Margaret R Dedloff, Zachary M Nash, Steven M Julio, Peggy A Cotter
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012084 (2024)
Little is known about oxygen utilization during infection by bacterial respiratory pathogens. The classical Bordetella species, including B. pertussis, the causal agent of human whooping cough, and B. bronchiseptica, which infects nearly all mammals,
Externí odkaz:
https://doaj.org/article/d770532abf8a4c2190520d596f075ad2
Autor:
Diana Andrea Fernandes de Abreu, Antonio Caballero, Pascal Fardel, Nicholas Stroustrup, Zhunan Chen, Kyunghwa Lee, William D Keyes, Zachary M Nash, Isaac F López-Moyado, Federico Vaggi, Astrid Cornils, Martin Regenass, Anca Neagu, Ivan Ostojic, Chang Liu, Yongmin Cho, Deniz Sifoglu, Yu Shen, Walter Fontana, Hang Lu, Attila Csikasz-Nagy, Coleen T Murphy, Adam Antebi, Eric Blanc, Javier Apfeld, Yun Zhang, Joy Alcedo, Queelim Ch'ng
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004225 (2014)
Insulin-like peptides (ILPs) play highly conserved roles in development and physiology. Most animal genomes encode multiple ILPs. Here we identify mechanisms for how the forty Caenorhabditis elegans ILPs coordinate diverse processes, including develo
Externí odkaz:
https://doaj.org/article/f2bbc108c2fa40b6adeeb728934d9508
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Two-partner secretion (TPS) systems are broadly distributed among Gram-negative bacteria and play important roles in bacterial pathogenesis. FhaB-FhaC is the prototypical member of the TPS family and we here identified the protease that initiates a p
Externí odkaz:
https://doaj.org/article/203a1c9d9e0745aea72e0d8bc1d5c36c
Autor:
Peggy A. Cotter, Zachary M. Nash
Publikováno v:
Molecular microbiologyReferences. 112(3)
Filamentous hemagglutinin (FHA) is a critically important virulence factor produced by Bordetella species that cause respiratory infections in humans and other animals. It is also a prototypical member of the widespread two partner secretion (TPS) pa
Autor:
Peggy A. Cotter, Zachary M. Nash
Publikováno v:
Microbiology Spectrum. 7
Bacteria use a variety of mechanisms to translocate proteins from the cytoplasm, where they are synthesized, to the cell surface or extracellular environment or directly into other cells, where they perform their ultimate functions. Type V secretion
Autor:
Isaac F. López-Moyado, Zachary M. Nash, Javier Apfeld, Walter Fontana, Bryne Ulmschneider, Nicholas Stroustrup
Publikováno v:
Nature methods
The measurement of lifespan pervades aging research. Because lifespan results from complex interactions between genetic, environmental and stochastic factors, it varies widely even among isogenic individuals. The actions of molecular mechanisms on li
Autor:
Isaac F. López-Moyado, Vivek Gowda, Walter Fontana, Zachary M. Nash, Javier Apfeld, Nicholas Stroustrup, Winston E. Anthony, Adam Gomez
Publikováno v:
Nature. 530(7588)
The process of ageing makes death increasingly likely, involving a random aspect that produces a wide distribution of lifespan even in homogeneous populations. The study of this stochastic behaviour may link molecular mechanisms to the ageing process
Autor:
Orian S. Shirihai, Shuxi Qiao, Xiufeng Song, Douangsone D. Vadysirisack, Richard T. Lee, John C. Reed, Marc Liesa, Zhifen Yang, Leif W. Ellisen, Devika Salunke, Michael Dennis, Shu-ichi Matsuzawa, Zachary M. Nash, Jun Yoshioka
Publikováno v:
Nature Communications
Macroautophagy (autophagy) is a critical cellular stress response; however, the signal transduction pathways controlling autophagy induction in response to stress are poorly understood. Here we reveal a new mechanism of autophagy control whose deregu
Autor:
Eric Blanc, Martin Regenass, Zhunan Chen, Deniz Sifoglu, Hang Lu, Joy Alcedo, Astrid Cornils, Isaac F. López-Moyado, Yu Shen, Yongmin Cho, Coleen T. Murphy, Anca Neagu, Ivan Ostojic, Quee-Lim Ch'ng, Zachary M. Nash, Attila Csikász-Nagy, Federico Vaggi, Chang Liu, William Keyes, Nicholas Stroustrup, KyungHwa Lee, Diana Andrea Fernandes de Abreu, Antonio Caballero, Javier Apfeld, Adam Antebi, Pascal Fardel, Yun Zhang, Walter Fontana
Publikováno v:
PLoS Genetics
PLoS Genet
Fernandes de Abreu, D, Caballero Reyes, A, Fardel, P, Stroustrup, N, Chen, Z, Lee, K, Keyes, W D, Nash, Z M, López-Moyado, I F, Vaggi, F, Cornils, A, Regenass, M, Neagu, A, Ostojic, I, Liu, M, Cho, Y, Sifoglu, D, Shen, Y, Fontana, W, Lu, H, Csikasz-Nagy, A, Murphy, C T, Antebi, A, Blanc, E, Apfeld, J, Zhang, Y, Alcedo, J & Ch'ng, Q 2014, ' An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology ', PL o S Genetics, vol. 10, no. 3, e1004225 . https://doi.org/10.1371/journal.pgen.1004225
PLoS Genetics, Vol 10, Iss 3, p e1004225 (2014)
PLoS Genet
Fernandes de Abreu, D, Caballero Reyes, A, Fardel, P, Stroustrup, N, Chen, Z, Lee, K, Keyes, W D, Nash, Z M, López-Moyado, I F, Vaggi, F, Cornils, A, Regenass, M, Neagu, A, Ostojic, I, Liu, M, Cho, Y, Sifoglu, D, Shen, Y, Fontana, W, Lu, H, Csikasz-Nagy, A, Murphy, C T, Antebi, A, Blanc, E, Apfeld, J, Zhang, Y, Alcedo, J & Ch'ng, Q 2014, ' An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology ', PL o S Genetics, vol. 10, no. 3, e1004225 . https://doi.org/10.1371/journal.pgen.1004225
PLoS Genetics, Vol 10, Iss 3, p e1004225 (2014)
Insulin-like peptides (ILPs) play highly conserved roles in development and physiology. Most animal genomes encode multiple ILPs. Here we identify mechanisms for how the forty Caenorhabditis elegans ILPs coordinate diverse processes, including develo