Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zachary L. Rodgers"'
Autor:
Xi Tian, Kyle C. Roche, Kin Man Au, Andrew Z. Wang, Feifei Yang, Yu Mi, Yuangzeng Min, Kyle Wagner, C. Tilden Hagan, Hayley Foley, Zachary L. Rodgers, Yusra Medik, Maofan Zhang
Publikováno v:
Biomaterials. 169:1-10
Most ovarian cancer patients respond well to initial platinum-based chemotherapy. However, within a year, many patients experience disease recurrence with a platinum resistant phenotype that responds poorly to second line chemotherapies. As a result,
Autor:
Jing Tian, Zachary L. Rodgers, C. Tilden Hagan, Andrew Z. Wang, Kyle Wagner, Feifei Yang, Kyle C. Roche, Kin Man Au, Yuanzeng Min, Maofan Zhang
Publikováno v:
Journal of Materials Chemistry B. 5:6049-6057
Chemoradiotherapy (CRT) with paclitaxel (PTX) and cisplatin (CP) is part of the standard of care for patients with locally advanced non-small cell lung cancer (NSCLC). Despite its high treatment intensity, many patients still develop local recurrence
Autor:
Zachary L. Rodgers, Song Ding, Weston J. Smith, Robert M. Hughes, Nathan P. Oien, David S. Lawrence, Christina M. Marvin
Publikováno v:
Angewandte Chemie International Edition. 55:16080-16083
A strategy for the light-activated release of bioactive compounds (BODIPY, colchicine, paclitaxel, and methotrexate) from membrane-enclosed depots is described. We have found that membrane-permeable bioagents can be rendered membrane impermeable by c
Autor:
Hannah L. Nowotarski, Zachary L. Rodgers, Alexander M. Brugh, Thomas A. Shell, Malcolm D. E. Forbes, David S. Lawrence
Publikováno v:
Inorganic Chemistry. 55:1962-1969
Cobalamins are known to react with thiols to yield stable β-axial Co(III)-S bonded thiolato-cobalamin complexes. However, in stark contrast to the Co-C bond in alkylcobalamins, the photolability of the Co-S bond in thiolato-cobalamins remains undete
Publikováno v:
Angewandte Chemie. 126:894-897
Although the corrin ring of vitamin B12 is unable to efficiently absorb light beyond 550 nm, it is shown that commercially available fluorophores can be used as antennas to capture long-wavelength light to promote scission of the Co-C bond at wavelen
Autor:
Robert M. Hughes, Christina M. Marvin, Zachary L. Rodgers, Song Ding, Nathan P. Oien, Weston J. Smith, David S. Lawrence
A strategy for the light-activated release of bioactive compounds (BODIPY, colchicine, paclitaxel, and methotrexate) from membrane-enclosed depots is described. We have found that membrane-permeable bioagents can be rendered membrane impermeable by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbbb970f02a45a40549ef06e93d4343
Autor:
Malcolm D. E. Forbes, David S. Lawrence, Laura M. Doherty, Jennifer R. Shell, Alexander M. Brugh, Andrew M. Moran, Brian P. Molesky, Robert M. Hughes, Zachary L. Rodgers
Publikováno v:
Journal of the American Chemical Society. 137(9)
Medical hydrogel applications have expanded rapidly over the past decade. Implantation in patients by noninvasive injection is preferred, but this requires hydrogel solidification from a low viscosity solution to occur in vivo via an applied stimuli.
Autor:
Christina M. Marvin, Nathan P. Oien, Weston J. Smith, Zachary L. Rodgers, David S. Lawrence, Junghyun Lee, Robert M. Hughes
Light-activatable drugs offer the promise of controlled release with exquisite temporal and spatial resolution. However, light-sensitive prodrugs are typically converted to their active forms using short-wavelength irradiation, which displays poor ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf7c5933d6ac3080b8aa21c9509109