Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zachary L. Quinn"'
Publikováno v:
The American Journal of the Medical Sciences. 364:371-378
Lung cancer remains the leading cause of cancer death in the United States and is unfortunately still frequently diagnosed in the metastatic setting, where the disease is considered incurable. Nearly 30% of these cancers may be driven by specific mut
Autor:
Karam Zakharia, Zachary L. Quinn, Hana Safah, Nakhle S. Saba, John J. Schmieg, Janet L. Schmid
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:e105-e112
Primary dural diffuse large B-cell lymphoma (PD-DLBCL) is a rare and aggressive B-cell non-Hodgkin lymphoma (NHL) that can present in intracranial or intraspinal locations. While the optimal management is unknown, PD-DLBCL therapy is often mirrored a
Publikováno v:
Journal of Clinical Oncology. 39:272-272
272 Background: Rule OP-35, which characterizes treatment-related complications of patients receiving outpatient chemotherapy that result in a potentially avoidable emergency department (ED) visit or hospitalization, was developed to encourage practi
Autor:
William Kevin Kelly, Guru Sonpavde, Russell Z. Szmulewitz, A. Oliver Sartor, Benjamin E. Leiby, Zachary L. Quinn, David J. Einstein, Eddy S. Yang
Publikováno v:
Journal of Clinical Oncology. 39:5036-5036
5036 Background: Rad is an alpha particle emitter that causes DNA double strand breaks and has been FDA-approved for use in mCRPC pts with bone metastases. PARP-1 activity critically supports androgen receptor (AR) activity in mCRPC and potentiates A
Publikováno v:
Journal of Clinical Oncology. 38:238-238
238 Background: For patients receiving cancer care, utilization of acute care resources can be frequent and, in many instances, is avoidable. At Thomas Jefferson University (TJU), up to 50% of emergency department (ED) visits for medical oncology pat
Publikováno v:
Journal of Clinical Oncology. 38:e19118-e19118
e19118 Background: For patients being treated for solid tumor malignancies, an unplanned hospitalization is a significant event that may help predict outcomes. Prior studies have demonstrated a 1 year mortality rate as high as 73% for oncology patien
Autor:
Ekaterina Bobrovnikova-Marjon, J. Alan Diehl, M. Celeste Simon, Daniel Ackerman, Zachary L. Quinn, Anthony A. Mancuso, Dionysios N. Giannoukos, Liping Liu, Michaela Gruber, Brian Keith, Regina M. Young
Solid tumors exhibit heterogeneous microenvironments, often characterized by limiting concentrations of oxygen (O2), glucose, and other nutrients. How oncogenic mutations alter stress response pathways, metabolism, and cell survival in the face of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c91ee20ceb94e817bf06cf919e0a86
https://europepmc.org/articles/PMC3672646/
https://europepmc.org/articles/PMC3672646/
Autor:
Rickson C. Mesquita, Brian Keith, Bryan L. Krock, M. Celeste Simon, Zachary L. Quinn, Lijoy K. Mathew, Jiaming Liang, Liping Liu, Amar J. Majmundar, Arjun G. Yodh, Nicolas Skuli, Meeri N. Kim, Anja Runge, Steven S. Schenkel
Publikováno v:
The Journal of clinical investigation. 122(4)
Localized tissue hypoxia is a consequence of vascular compromise or rapid cellular proliferation and is a potent inducer of compensatory angiogenesis. The oxygen-responsive transcriptional regulator hypoxia-inducible factor 2α (HIF-2α) is highly ex
Autor:
Zachary L. Quinn, Anthony A. Mancuso, M. Celeste Simon, Brian Keith, J. Alan Diehl, Daniel Ackerman, Regina M. Young, Liping Liu, Ekaterina Bobovnikova-Marjon, Dionysios N. Giannoukos, Michaela Gruber
Publikováno v:
Cancer Research. 73:IA16-IA16
Solid tumors exhibit heterogeneous microenvironments, often characterized by limiting concentrations of oxygen (O2), glucose, and other nutrients. How oncogenic mutations alter stress response pathways, metabolism, and cell survival in the face of th