Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zachary L. Niemeyer"'
Autor:
Tobias Gensch, Benjamin Murray, Shibin Zhao, Matthew S. Sigman, Mark R. Biscoe, Zachary L. Niemeyer
Publikováno v:
Science. 362:670-674
The staying power of electron-poor ligands The venerable Suzuki coupling reaction originally used palladium to pair up unsaturated carbon centers. The protocol has been widely extended to chiral saturated alkyl carbons, but control over product stere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537ee8b4c339f2531f250a4aaf4b30f0
https://doi.org/10.1126/science.aat2299
https://doi.org/10.1126/science.aat2299
Autor:
Zhi Ren, Djamaladdin G. Musaev, Wenbin Liu, Matthew S. Sigman, Huw M. L. Davies, John Bacsa, Kuangbiao Liao, Zachary L. Niemeyer
Publikováno v:
ACS Catalysis. 8:678-682
Three types of dirhodium tetrakis(triarylcyclopropanecarboxylate) complexes were generated and shown to adopt disparate high-symmetry structures. These catalysts were evaluated in the intermolecular C–H functionalization of an array of terminally s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37cedfef9d97274671a5c9bcd6b69cfd
https://doi.org/10.1021/acscatal.7b03421
https://doi.org/10.1021/acscatal.7b03421
Publikováno v:
Organometallics. 37:203-210
Delineating complex ligand effects on enantioselectivity is a longstanding challenge in asymmetric catalysis. With α-amino acid ligands, the essential difficulty lies in accurately describing integrated perturbations induced by simultaneous variatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c14f2c0bc5661c50e8b525c2be2d0a
https://doi.org/10.1021/acs.organomet.7b00751
https://doi.org/10.1021/acs.organomet.7b00751
Autor:
Amanda J. Bischoff, Mohammad Movassaghi, Zachary L. Niemeyer, Brandon M. Nelson, Matthew S. Sigman
Publikováno v:
Journal of the American Chemical Society. 139:15539-15547
The bis(pyridine)silver (I) permanganate promoted hydroxylation of diketopiperazines has served as a pivotal transformation in the synthesis of complex epipolythiodiketopiperazine alkaloids. This late-stage C–H oxidation chemistry is strategically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1def5f897741cc432368e099b2915c9c
https://doi.org/10.1021/jacs.7b09541
https://doi.org/10.1021/jacs.7b09541
Publikováno v:
Nature Chemistry. 8:610-617
The mechanistic foundation behind the identity of a phosphine ligand that best promotes a desired reaction outcome is often non-intuitive, and thus has been addressed in numerous experimental and theoretical studies. In this work, multivariate correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1790e96527e6a34269f0bc101abebca2
https://doi.org/10.1038/nchem.2501
https://doi.org/10.1038/nchem.2501
Autor:
Clayton P. Owens, N. Mac E Weldy, S. Chen, Cameron Herting, Zachary L. Niemeyer, Andrew G. Schafer, Simon B. Blakey, Adrián Varela-Álvarez, Huw M. L. Davies, Matthew S. Sigman, Djamaladdin G. Musaev
Publikováno v:
Chemical Science. 7:3142-3146
The intermolecular enantioselective C–H functionalization with acceptor-only metallocarbenes is reported using a new family of Ir(III)-bis(imidazolinyl)phenyl catalysts, developed based on the interplay of experimental and computational insights. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f3d7e389b1bb03fbcb0f30bd3cde91
https://doi.org/10.1039/c6sc00190d
https://doi.org/10.1039/c6sc00190d
Autor:
Dimitri A. Khrakovsky, F. Dean Toste, Cynthia M. Hong, Zachary L. Niemeyer, Matthew S. Sigman, Christian N. Kuzniewski, Leo A. Joyce, Suresh Pindi
Publikováno v:
Journal of the American Chemical Society, vol 139, iss 37
Niemeyer, ZL; Pindi, S; Khrakovsky, DA; Kuzniewski, CN; Hong, CM; Joyce, LA; et al.(2017). Parameterization of Acyclic Diaminocarbene Ligands Applied to a Gold(I)-Catalyzed Enantioselective Tandem Rearrangement/Cyclization. Journal of the American Chemical Society, 139(37), 12943-12946. doi: 10.1021/jacs.7b08791. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/41x9h5sz
Niemeyer, ZL; Pindi, S; Khrakovsky, DA; Kuzniewski, CN; Hong, CM; Joyce, LA; et al.(2017). Parameterization of Acyclic Diaminocarbene Ligands Applied to a Gold(I)-Catalyzed Enantioselective Tandem Rearrangement/Cyclization. Journal of the American Chemical Society, 139(37), 12943-12946. doi: 10.1021/jacs.7b08791. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/41x9h5sz
© 2017 American Chemical Society. Computed descriptors for acyclic diaminocarbene ligands are developed in the context of a gold catalyzed enantioselective tandem [3,3]-sigmatropic rearrangement-[2+2]-cyclization. Surrogate structures enable the rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e83e9ec8f841f872a50c7f912afcab
https://escholarship.org/uc/item/41x9h5sz
https://escholarship.org/uc/item/41x9h5sz
Publikováno v:
Journal of the American Chemical Society. 139(31)
A new catalyst system capable of selective chloride functionalization in the Pd-catalyzed amination of 3,2- and 5,2- Br/Cl-pyridines is reported. A reaction optimization strategy employing ligand parametrization led to the identification of 1,1′-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e70e6fe86e036c3666b341736671ab
https://pubmed.ncbi.nlm.nih.gov/28715180
https://pubmed.ncbi.nlm.nih.gov/28715180
Publikováno v:
Christian, AH; Niemeyer, ZL; Sigman, MS; & Toste, FD. (2017). Uncovering Subtle Ligand Effects of Phosphines Using Gold(I) Catalysis. ACS Catalysis, 7(6), 3973-3978. doi: 10.1021/acscatal.7b00757. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/88k3h41m
ACS catalysis, vol 7, iss 6
ACS catalysis, vol 7, iss 6
© 2017 American Chemical Society. Herein, we report the integration of simple linear regressions with gold(I) catalysis to interrogate the influence of phosphine structure on metal-catalyzed organic transformations. We demonstrate that observed prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6d8740fac4e1502ce659444cf6acf8
http://www.escholarship.org/uc/item/88k3h41m
http://www.escholarship.org/uc/item/88k3h41m
Publikováno v:
The Journal of Organic Chemistry
Synthetically useful radical thiol-ene reactions can be initiated by visible light irradiation in the presence of transition metal polypyridyl photocatalysts. The success of this method relies upon the use of p-toluidine as an essential additive. Usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a644f0ad1f2dc20441577cc2d23e4b
https://doi.org/10.1021/jo500031g
https://doi.org/10.1021/jo500031g