Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Zachary L Fuller"'
Publikováno v:
eLife, Vol 12 (2023)
Causal loss-of-function (LOF) variants for Mendelian and severe complex diseases are enriched in 'mutation intolerant' genes. We show how such observations can be interpreted in light of a model of mutation-selection balance and use the model to rela
Externí odkaz:
https://doaj.org/article/7cfc56c5bf724df09e38c99b0144778c
Autor:
William R Milligan, Zachary L Fuller, Ipsita Agarwal, Michael B Eisen, Molly Przeworski, Guy Sella
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255680 (2021)
New emerging infectious diseases are identified every year, a subset of which become global pandemics like COVID-19. In the case of COVID-19, many governments have responded to the ongoing pandemic by imposing social policies that restrict contacts o
Externí odkaz:
https://doaj.org/article/bdc2c23abbb4473cb74d6a850dacc09d
Autor:
Raúl A. González-Pech, Jihanne Shepherd, Zachary L. Fuller, Todd C. LaJeunesse, John Everett Parkinson
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Cladocopium infistulum (Symbiodiniaceae) is a dinoflagellate specialized to live in symbiosis with western Pacific giant clams (Tridacnidae). Unlike coral-associated symbionts, which reside within the host cells, C. infistulum inh
Externí odkaz:
https://doaj.org/article/9bb537fd5e6244c9a54252d37b5f8f9a
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007526 (2018)
Understanding the role of chromosomal inversions in speciation is a fundamental problem in evolutionary genetics. Here, we perform a comprehensive reconstruction of the evolutionary histories of the chromosomal inversions in Drosophila persimilis and
Externí odkaz:
https://doaj.org/article/c6d5ce2d56d04f4381532b6aa3e68d45
Publikováno v:
eLife. 12
Causal loss-of-function (LOF) variants for Mendelian and severe complex diseases are enriched in 'mutation intolerant' genes. We show how such observations can be interpreted in light of a model of mutation-selection balance and use the model to rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a7f31030e3e15cd1a122f628cef48bd
https://doi.org/10.7554/elife.83172
https://doi.org/10.7554/elife.83172
When adaptive phenotypic variation or QTLs map within an inverted segment of a chromosome, researchers often despair because it is thought that the suppression of crossing over will prevent the discovery of selective target genes through fine scale g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08e30a0133473ddb109bd5810d49572c
https://doi.org/10.1101/2022.08.15.503618
https://doi.org/10.1101/2022.08.15.503618
Causal loss-of-function (LOF) variants for Mendelian and severe complex diseases are enriched in “mutation intolerant” genes. We show how such observations can be interpreted in light of a model of mutation-selection balance, and use the model to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff115fb420204fcb264ae9d1e46d18c
https://doi.org/10.1101/2022.08.11.503594
https://doi.org/10.1101/2022.08.11.503594
Autor:
Lesley T. Lancaster, Zachary L. Fuller, David Berger, Matthew A. Barbour, Sissel Jentoft, Maren Wellenreuther
Publikováno v:
The Journal of animal ecologyREFERENCES. 91(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1915e8b560a120a96af27eeef6eaa21c
https://pubmed.ncbi.nlm.nih.gov/34582573
https://pubmed.ncbi.nlm.nih.gov/34582573
Publikováno v:
Resuscitation
Background Cerebral edema after cardiac arrest may be a modifiable cause of secondary brain injury. We aimed to identify processes of care associated with recovery in a cohort of patients with mild to moderate edema. Methods We conducted a retrospect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ed86edd4a722e7f47536fbc64b6028
https://doi.org/10.1016/j.resuscitation.2021.02.033
https://doi.org/10.1016/j.resuscitation.2021.02.033