Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zachary Kohutek"'
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S6 shows phylogenies based on point mutations with UV signature mutations removed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f164bba3f3f32ada1a3f4bfbb99cc4
https://doi.org/10.1158/1078-0432.22479737
https://doi.org/10.1158/1078-0432.22479737
Tables S1-S8 from The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Supplementary Tables S1-S8 show the samples used for study (Table S1), the somatic single nucleotide variants, small insertions and small deletions (Table S2), the somatic copy number alterations anallyzed (Table S3), the gene list used to analyze so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b4139b47cb30c51b6cd5befd1a5b0
https://doi.org/10.1158/1078-0432.22479734.v1
https://doi.org/10.1158/1078-0432.22479734.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S5 shows the Jaccard similarity coefficients across the seven melanoma cases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db7d12acbce5e61cdbd8d5ee4d5c9f6
https://doi.org/10.1158/1078-0432.22479740
https://doi.org/10.1158/1078-0432.22479740
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S1 shows sequencing results, somatic copy number, and whole genome duplication analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc902e38c6cc4fb91699531f29ea5702
https://doi.org/10.1158/1078-0432.22479752
https://doi.org/10.1158/1078-0432.22479752
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Purpose:Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6224543d5704e454172689636f33e8cd
https://doi.org/10.1158/1078-0432.c.6530294
https://doi.org/10.1158/1078-0432.c.6530294
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S2 shows the pattern of C>T mutations at dipyrimidines and nondipyrimidines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f841ee6cc0d1ebb59493c3a1ae4257
https://doi.org/10.1158/1078-0432.22479749.v1
https://doi.org/10.1158/1078-0432.22479749.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S3 shows mutation signatures identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a46536067e488ee8203c503c5414e8
https://doi.org/10.1158/1078-0432.22479746.v1
https://doi.org/10.1158/1078-0432.22479746.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S4 shows mutation signatures identified using Palimpsest.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40885dc789bdb73c909aa849ec9e4233
https://doi.org/10.1158/1078-0432.22479743
https://doi.org/10.1158/1078-0432.22479743
Autor:
Amanda Zucker, Christine A. Iacobuzio-Donahue, Rachel Karchin, Jody E. Hooper, Vladimir Makarov, Nicholas D. Socci, Timothy A. Chan, Paul B. Chapman, Barry S. Taylor, Jungeui Hong, Suzanne L. Topalian, Michael A. Postow, Priscilla Baez, Rajya Kappagantula, David B. Solit, Akimasa Hayashi, Zachary Kohutek, Nadeem Riaz, Collin Tokheim, Alvin Makohon-Moore, Craig M. Bielski, Evan J. Lipson
Publikováno v:
Clin Cancer Res
Purpose: Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multile
Autor:
Daniel France, Paromita Nath, Sankaran Mahadevan, Jason Slagle, Rajiv Agarwal, Zachary Kohutek, Erin Alexis Gillaspie, Sarah Rohde, Akhil Choudhary, Joyce Harris, Evan Rhodes, Carrie Reale, Shilo Anders, Laurie Novak, Adam Wright, Robert Freundlich, Kim Unertl, Matthew B Weinger
Publikováno v:
Journal of Clinical Oncology. 39:e13560-e13560
e13560 Background: A common cause of preventable harm is the failure to detect and appropriately respond to clinical deterioration. Timely intervention is needed, particularly in cancer patients, to mitigate the effects of adverse events, disease pro